7E75

Crystal structure of human ERK2 mutant (G37C)

Summary for 7E75

Entry DOI	10.2210/pdb7e75/pdb
Descriptor	Mitogen-activated protein kinase 1 (2 entities in total)
Functional Keywords	kinase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	41773.02
Authors	Park, Y.S.,Kim, M.,Ryu, S.E. (deposition date: 2021-02-25, release date: 2022-03-02, Last modification date: 2023-11-29)
Primary citation	Park, Y.,Kim, M.,Ryu, S.E. Structural mechanism of inhibitor-resistance by ERK2 mutations Biodesign, 9:14-18, 2021 Cited by DOI: 10.34184/kssb.2021.9.1.14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.481 Å)

Structure validation