1N4E
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a DNA decamer containing a cis-syn thymine dimer. Proc.Natl.Acad.Sci.USA, 99, 2002
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6BA5
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3V6R
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3V6S
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5BTM
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3RF3
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1SM5
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*(BRU)P*TP*AP*AP*TP*(BRU)P*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C. | Deposit date: | 2004-03-08 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a DNA Decamer Containing a Thymine-dimer Proc.Natl.Acad.Sci.USA, 99, 2002
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1T4I
| Crystal Structure of a DNA Decamer Containing a Thymine-dimer | Descriptor: | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | Authors: | Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C. | Deposit date: | 2004-04-29 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer Proc.Natl.Acad.Sci.USA, 99, 2002
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6OSV
| Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | Descriptor: | Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 | Authors: | Park, H, Rader, C. | Deposit date: | 2019-05-02 | Release date: | 2020-04-01 | Last modified: | 2020-05-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
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3TJ5
| human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii | Descriptor: | Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | Deposit date: | 2011-08-23 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J.Biol.Chem., 286, 2011
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3TJ6
| human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii | Descriptor: | Antigenic heat-stable 120 kDa protein, Vinculin | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | Deposit date: | 2011-08-23 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J.Biol.Chem., 286, 2011
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1YPU
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1YPO
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1YPQ
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6BAN
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6N2U
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6AVK
| Streptavidin bound to peptide-like compound KPM-6 | Descriptor: | 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin | Authors: | Park, H, Shamim, R, McEnaney, P, Kodadek, T. | Deposit date: | 2017-09-02 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer To be Published
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4ZZ7
| Crystal structure of methylmalonate-semialdehyde dehydrogenase (DddC) from Oceanimonas doudoroffii | Descriptor: | Methylmalonate-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Do, H, Lee, C.W, Lee, S.G, Kang, H, Park, C.M, Kim, H.J, Park, H, Park, H, Lee, J.H. | Deposit date: | 2015-05-22 | Release date: | 2016-04-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure and modeling of the tetrahedral intermediate state of methylmalonate-semialdehyde dehydrogenase (MMSDH) from Oceanimonas doudoroffii. J. Microbiol., 54, 2016
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4RHE
| Crystal structure of UbiX, an aromatic acid decarboxylase from the Colwellia psychrerythraea 34H | Descriptor: | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, FLAVIN MONONUCLEOTIDE, SULFATE ION | Authors: | Do, H, Kim, S.J, Lee, C.W, Kim, H.-W, Park, H.H, Kim, H.M, Park, H, Park, H.J, Lee, J.H. | Deposit date: | 2014-10-02 | Release date: | 2015-02-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes. Sci Rep, 5, 2015
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4RHF
| Crystal structure of UbiX mutant V47S from Colwellia psychrerythraea 34H | Descriptor: | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, SULFATE ION | Authors: | Do, H, Kim, S.J, Lee, C.W, Kim, H.-W, Park, H.H, Kim, H.M, Park, H, Park, H.J, Lee, J.H. | Deposit date: | 2014-10-02 | Release date: | 2015-02-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.764 Å) | Cite: | Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes. Sci Rep, 5, 2015
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4E71
| Crystal structure of the RHO GTPASE binding domain of Plexin B2 | Descriptor: | Plexin-B2, SODIUM ION | Authors: | Guan, X, Wang, H, Tempel, W, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2012-03-16 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structure of the RHO GTPASE binding domain of Plexin B2 to be published
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4E74
| Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A | Descriptor: | Plexin-A4, UNKNOWN ATOM OR ION | Authors: | Guan, X, Wang, H, Tempel, W, Dong, A, Tong, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2012-03-16 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A to be published
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3ME3
| Activator-Bound Structure of Human Pyruvate Kinase M2 | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 3-{[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl}aniline, Pyruvate kinase isozymes M1/M2, ... | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-31 | Release date: | 2010-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat.Chem.Biol., 8, 2012
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6CZ1
| Crystal structure of ATPase domain of Human GRP78 bound to Ver155008 | Descriptor: | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Endoplasmic reticulum chaperone BiP, MAGNESIUM ION | Authors: | Antoshchenko, T, Chen, Y, Hughes, S, Park, H. | Deposit date: | 2018-04-07 | Release date: | 2019-04-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystallographic selection of adenosine analogs that fit the mold of the active site of human GRP78 and beyond To be Published
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6D0S
| RabGAP domain of human TBC1D22B | Descriptor: | SULFATE ION, TBC1 domain family member 22B, UNKNOWN ATOM OR ION | Authors: | Tong, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2018-04-10 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | RabGAP domain of human TBC1D22B To be Published
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