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PDB: 254 件

8EN2
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Structure of GII.10 norovirus in complex with Nanobody 34
分子名称: 1,2-ETHANEDIOL, GII.10 P domain, Nanobody 34
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EMY
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BU of 8emy by Molmil
Structure of GII.4 norovirus in complex with Nanobody 82
分子名称: 1,2-ETHANEDIOL, GII.4 P domain, Nanobody 82
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN3
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BU of 8en3 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 45
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1, Nanobody 45
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
6WT3
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BU of 6wt3 by Molmil
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-05-01
公開日2020-07-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
5LGJ
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BU of 5lgj by Molmil
THE CRYSTAL STRUCTURE OF IGE FC MUTANT - P333C
分子名称: GLYCEROL, Ig epsilon chain C region, SULFATE ION, ...
著者Dhaliwal, B, Pang, M.O.Y, Sutton, B.J.
登録日2016-07-07
公開日2017-03-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献THE CRYSTAL STRUCTURE OF IGE FC MUTANT - P333C
To Be Published
6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-05
公開日2018-11-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6WN4
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BU of 6wn4 by Molmil
Structural basis for the binding of monoclonal antibody 5D2 to the tryptophan-rich lipid-binding loop in lipoprotein lipase
分子名称: 5D2 FAB HEAVY CHAIN, 5D2 FAB LIGHT CHAIN, Lipoprotein lipase peptide
著者Luz, J.G, Birrane, G, Young, S.G, Meiyappan, M, Ploug, M.
登録日2020-04-22
公開日2020-07-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase.
J.Lipid Res., 61, 2020
5LGK
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BU of 5lgk by Molmil
Crystal structure of the human IgE-Fc bound to its B cell receptor derCD23
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, ...
著者Dhaliwal, B, Pang, M.O.Y, Sutton, B.J.
登録日2016-07-07
公開日2017-04-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献IgE binds asymmetrically to its B cell receptor CD23.
Sci Rep, 7, 2017
6P8N
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BU of 6p8n by Molmil
Crystal Structure of Antibody P-p1f1 in Complex with eOD-GT8
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2019-06-07
公開日2019-11-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell Rep, 29, 2019
6PEH
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BU of 6peh by Molmil
Crystal structure of rabbit monoclonal anti-HIV antibody 1C2
分子名称: 1C2 Fab Heavy Chain, 1C2 Fab Light Chain, SULFATE ION
著者Liban, T, Pancera, M.
登録日2019-06-20
公開日2019-11-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.296 Å)
主引用文献Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity, 51, 2019
6XQW
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BU of 6xqw by Molmil
Crystal Structure of MaliM03 Fab in complex with Pfmsp1-19
分子名称: MaliM03 Fab Heavy Chain, MaliM03 Fab Light Chain, Pfmsp1-19
著者Singh, S, Pancera, M.
登録日2020-07-10
公開日2021-03-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.
J.Exp.Med., 218, 2021
6XOC
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BU of 6xoc by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotypic iv4 Fab
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-07-06
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6P8M
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BU of 6p8m by Molmil
Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2019-06-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.594 Å)
主引用文献Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell Rep, 29, 2019
6VLW
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BU of 6vlw by Molmil
Crystal Structure of 426cOD in Complex with VRC01 Fab
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 426cOD, ...
著者Weidle, C, Pancera, M.
登録日2020-01-27
公開日2020-12-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献HIV-1 VRC01 Germline-Targeting Immunogens Select Distinct Epitope-Specific B Cell Receptors.
Immunity, 53, 2020
6VRQ
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BU of 6vrq by Molmil
Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-02-08
公開日2021-02-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6WAS
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BU of 6was by Molmil
Structure of D19.PA8 Fab in complex with 1FD6 16055 V1V2 scaffold
分子名称: 1FD6 16055 V1V2 scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, GN1_PA8 Fab Heavy chain, ...
著者Singh, S, Liban, T.J, Pancera, M.
登録日2020-03-26
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6OL5
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BU of 6ol5 by Molmil
Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6OL6
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BU of 6ol6 by Molmil
Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
分子名称: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
著者Weidle, C, Pancera, M, Gewe, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6VJN
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BU of 6vjn by Molmil
Structure of NHP D11A.B5Fab in complex with 16055 V2b peptide
分子名称: D11A.B5 Fab Heavy chain, D11A.B5 Fab Light chain, SODIUM ION, ...
著者Singh, S, Liban, T.J, Pancera, M.
登録日2020-01-16
公開日2021-01-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6OL7
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BU of 6ol7 by Molmil
Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.419 Å)
主引用文献Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
J.Exp.Med., 216, 2019
8DG9
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BU of 8dg9 by Molmil
Cryo-EM Structure of RSV prefusion F trimer in complex with three MxR Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAb MxR Heavy Chain, ...
著者Rodarte, J.V, Pancera, M.
登録日2022-06-23
公開日2023-02-22
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
8DG8
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BU of 8dg8 by Molmil
Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3x1 monoclonal antibody, VH region, ...
著者Rodarte, J.V, Pancera, M.
登録日2022-06-23
公開日2023-02-22
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
6WIT
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BU of 6wit by Molmil
Crystal structure of NHP D15.SD7 Fab in complex with 16055 V1V2 1FD6 scaffold
分子名称: 16055 V1V2 1FD6 Scaffold, 2-acetamido-2-deoxy-beta-D-glucopyranose, NHP GN1-SD7 Fab Heavy Chain, ...
著者Liban, T, Aljedani, S, Rodarte, J, Pancera, M.
登録日2020-04-10
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6WRP
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BU of 6wrp by Molmil
Crystal Structure of PI3-E12 Fab, An Antibody Against Human Parainfluenza Virus Type III
分子名称: 1,2-ETHANEDIOL, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Weidle, C, Pancera, M.
登録日2020-04-29
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Protective antibodies against human parainfluenza virus type 3 infection.
Mabs, 13, 2021
6XLZ
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BU of 6xlz by Molmil
Structure of NHP D11A.F2 Fab in complex with 16055 V2b peptide
分子名称: (R,R)-2,3-BUTANEDIOL, Envelope glycoprotein gp160, NHP_D11A.F2_Fab_Heavy_chain, ...
著者Aljedani, S, Rodarte, J, Liban, T, Pancera, M.
登録日2020-06-29
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021

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件を2024-10-30に公開中

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