4TQQ
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![BU of 4tqq by Molmil](/molmil-images/mine/4tqq) | Photosynthetic Reaction Center from R. sphaeroides Analyzed at Room Temperature on an X-ray Transparent Microfluidic Chip | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ... | Authors: | Schieferstein, J.M, Khvostichenko, D.S, Pawate, A.S, Kenis, P.J.A. | Deposit date: | 2014-06-11 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination. Cryst.Growth Des., 14, 2014
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4U98
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![BU of 4u98 by Molmil](/molmil-images/mine/4u98) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (AppCp complex) | Descriptor: | MAGNESIUM ION, Maltokinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2014-08-05 | Release date: | 2015-02-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
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4U94
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![BU of 4u94 by Molmil](/molmil-images/mine/4u94) | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway | Descriptor: | MAGNESIUM ION, Maltokinase | Authors: | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2014-08-05 | Release date: | 2015-02-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.473 Å) | Cite: | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway. Sci Rep, 5, 2015
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3QNE
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![BU of 3qne by Molmil](/molmil-images/mine/3qne) | Candida albicans seryl-tRNA synthetase | Descriptor: | Seryl-tRNA synthetase, cytoplasmic | Authors: | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2011-02-08 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO5
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![BU of 3qo5 by Molmil](/molmil-images/mine/3qo5) | Crystal Structure of the seryl-tRNA synthetase from Candida albicans | Descriptor: | Seryl-tRNA synthetase, cytoplasmic | Authors: | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2011-02-09 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen. Proc.Natl.Acad.Sci.USA, 108, 2011
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7SGD
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![BU of 7sgd by Molmil](/molmil-images/mine/7sgd) | Lassa virus glycoprotein construct(Josiah GPCysR4) recovered from GPC-I53-50 nanoparticle by localized reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Antanasijevic, A, Brouwer, P.J.M, Ward, A.B. | Deposit date: | 2021-10-05 | Release date: | 2022-10-12 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection. Cell Host Microbe, 30, 2022
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8SDC
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![BU of 8sdc by Molmil](/molmil-images/mine/8sdc) | Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | Descriptor: | Alpha/beta hydrolase fold protein, CHLORIDE ION | Authors: | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | Deposit date: | 2023-04-06 | Release date: | 2023-09-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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5M3N
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![BU of 5m3n by Molmil](/molmil-images/mine/5m3n) | HTRA2 wild-type structure | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | Authors: | Merski, M, Pereira, P.J.B, Macedo-Ribeiro, S. | Deposit date: | 2016-10-15 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2. Cell Death Dis, 8, 2017
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7PZT
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![BU of 7pzt by Molmil](/molmil-images/mine/7pzt) | Structure of the bacterial toxin, TecA, an asparagine deamidase from Alcaligenes faecalis. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Urea amidohydrolase | Authors: | Dix, S.R, Aziz, A.A, Baker, P.J, Evans, C.A, Dickman, M.J, Farthing, R.J, King, Z.L.S, Nathan, S, Partridge, L.J, Raih, F.M, Sedelnikova, S.E, Thomas, M.S, Rice, D.W. | Deposit date: | 2021-10-13 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The structure of A. faecalis TecA provides insights into its role as an asparagine deamidase toxin which targets RhoA To Be Published
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8SDD
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![BU of 8sdd by Molmil](/molmil-images/mine/8sdd) | Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate | Descriptor: | Alpha/beta hydrolase fold protein | Authors: | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | Deposit date: | 2023-04-06 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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2UZX
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![BU of 2uzx by Molmil](/molmil-images/mine/2uzx) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB: Crystal form I | Descriptor: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | Authors: | Niemann, H.H, Jager, V, Butler, P.J.G, Van Den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | Deposit date: | 2007-05-02 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
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2UZY
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![BU of 2uzy by Molmil](/molmil-images/mine/2uzy) | Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein inlb: low resolution, Crystal form II | Descriptor: | HEPATOCYTE GROWTH FACTOR RECEPTOR, INTERNALIN B | Authors: | Niemann, H.H, Jager, V, Butler, P.J.G, van den Heuvel, J, Schmidt, S, Ferraris, D, Gherardi, E, Heinz, D.W. | Deposit date: | 2007-05-02 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of the Human Receptor Tyrosine Kinase met in Complex with the Listeria Invasion Protein Inlb Cell(Cambridge,Mass.), 130, 2007
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4IS4
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![BU of 4is4 by Molmil](/molmil-images/mine/4is4) | |
1TT6
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![BU of 1tt6 by Molmil](/molmil-images/mine/1tt6) | The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | Descriptor: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-06-22 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
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6N7B
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![BU of 6n7b by Molmil](/molmil-images/mine/6n7b) | Structure of the human JAK1 kinase domain with compound 38 | Descriptor: | GLYCEROL, N-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrazolo[4,3-c]pyridine-7-carboxamide, Tyrosine-protein kinase JAK1 | Authors: | Lupardus, P.J, Brown, D. | Deposit date: | 2018-11-27 | Release date: | 2019-04-24 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Bioorg.Med.Chem.Lett., 29, 2019
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6N79
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![BU of 6n79 by Molmil](/molmil-images/mine/6n79) | Structure of the human JAK1 kinase domain with compound 20 | Descriptor: | GLYCEROL, N-{5-[5-chloro-2-(difluoromethoxy)phenyl]-1H-pyrazol-4-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide, Tyrosine-protein kinase JAK1 | Authors: | Lupardus, P.J, Brown, D. | Deposit date: | 2018-11-27 | Release date: | 2019-04-24 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Bioorg.Med.Chem.Lett., 29, 2019
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1S4D
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![BU of 1s4d by Molmil](/molmil-images/mine/1s4d) | Crystal Structure Analysis of the S-adenosyl-L-methionine dependent uroporphyrinogen-III C-methyltransferase SUMT | Descriptor: | GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, Uroporphyrin-III C-methyltransferase | Authors: | Vevodova, J, Graham, R.M, Raux, E, Schubert, H.L, Roper, D.I, Brindley, A.A, Scott, A.I, Roessner, C.A, Stamford, N.P.J, Stroupe, M.E, Getzoff, E.D, Warren, M.J, Wilson, K.S. | Deposit date: | 2004-01-16 | Release date: | 2004-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure/Function Studies on a S-Adenosyl-l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis J.Mol.Biol., 344, 2004
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7TPU
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![BU of 7tpu by Molmil](/molmil-images/mine/7tpu) | Crystal structure of a chitinase-modifying protein from Fusarium vanettenii (Fvan-cmp) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-lactamase domain-containing protein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Dowling, N.V, Naumann, T.A, Price, N.P.J, Rose, D.R. | Deposit date: | 2022-01-26 | Release date: | 2023-02-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Crystal structure of a polyglycine hydrolase determined using a RoseTTAFold model. Acta Crystallogr D Struct Biol, 79, 2023
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6N78
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![BU of 6n78 by Molmil](/molmil-images/mine/6n78) | Structure of the human JAK1 kinase domain with compound 21 | Descriptor: | GLYCEROL, N-{3-[5-chloro-2-(difluoromethoxy)phenyl]-1-methyl-1H-pyrazol-4-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide, Tyrosine-protein kinase JAK1 | Authors: | Lupardus, P.J, Brown, D. | Deposit date: | 2018-11-27 | Release date: | 2019-04-24 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Bioorg.Med.Chem.Lett., 29, 2019
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6N7A
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![BU of 6n7a by Molmil](/molmil-images/mine/6n7a) | Structure of the human JAK1 kinase domain with compound 39 | Descriptor: | GLYCEROL, N-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1H-pyrazol-4-yl]-2-methyl-2H-pyrazolo[4,3-c]pyridine-7-carboxamide, Tyrosine-protein kinase JAK1 | Authors: | Lupardus, P.J, Brown, D. | Deposit date: | 2018-11-27 | Release date: | 2019-04-24 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Bioorg.Med.Chem.Lett., 29, 2019
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6N7C
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![BU of 6n7c by Molmil](/molmil-images/mine/6n7c) | Structure of the human JAK1 kinase domain with compound 56 | Descriptor: | GLYCEROL, N-[5-(3-methoxynaphthalen-2-yl)-1H-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, Tyrosine-protein kinase JAK1 | Authors: | Lupardus, P.J, Brown, D. | Deposit date: | 2018-11-27 | Release date: | 2019-04-24 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling. Bioorg.Med.Chem.Lett., 29, 2019
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1TZ8
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![BU of 1tz8 by Molmil](/molmil-images/mine/1tz8) | The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol | Descriptor: | ACETATE ION, CARBONATE ION, DIETHYLSTILBESTROL, ... | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-07-09 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
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5NHU
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![BU of 5nhu by Molmil](/molmil-images/mine/5nhu) | |
2X79
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![BU of 2x79 by Molmil](/molmil-images/mine/2x79) | Inward facing conformation of Mhp1 | Descriptor: | HYDANTOIN TRANSPORT PROTEIN | Authors: | Shimamura, T, Weyand, S, Beckstein, O, Rutherford, N.G, Hadden, J.M, Sharples, D, Sansom, M.S.P, Iwata, S, Henderson, P.J.F, Cameron, A.D. | Deposit date: | 2010-02-25 | Release date: | 2010-05-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1. Science, 328, 2010
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7Q9B
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![BU of 7q9b by Molmil](/molmil-images/mine/7q9b) | MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-11-12 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy. Cell, 186, 2023
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