8SMF
| Structure of SPO1 phage Tad2 in complex with 1''-3' gcADPR | 分子名称: | (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione, Gp34.65, MAGNESIUM ION | 著者 | Lu, A, Yirmiya, E, Leavitt, A, Avraham, C, Osterman, I, Garb, J, Antine, S.P, Mooney, S.E, Hobbs, S.J, Amitai, G, Sorek, R, Kranzusch, P.J. | 登録日 | 2023-04-26 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Phages overcome bacterial immunity via diverse anti-defence proteins. Nature, 625, 2024
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8SME
| Structure of SPO1 phage Tad2 in apo state | 分子名称: | Gp34.65 | 著者 | Lu, A, Yirmiya, E, Leavitt, A, Avraham, C, Osterman, I, Garb, J, Antine, S.P, Mooney, S.E, Hobbs, S.J, Amitai, G, Sorek, R, Kranzusch, P.J. | 登録日 | 2023-04-26 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Phages overcome bacterial immunity via diverse anti-defence proteins. Nature, 625, 2024
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2GJ7
| Crystal Structure of a gE-gI/Fc complex | 分子名称: | Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J. | 登録日 | 2006-03-30 | 公開日 | 2006-05-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging. Plos Biol., 4, 2006
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5XSK
| Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*TP*GP*GP*TP*CP*TP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*AP*GP*AP*CP*CP*A)-3'), ... | 著者 | Chen, L.Y, Huang, Y.C, Hsieh, Y.C, Lin, P.J, Chen, C.J. | 登録日 | 2017-06-14 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structure of PWWP-DNA complex at 2.84 Angstroms resolution To Be Published
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5MER
| Human Leukocyte Antigen A02 presenting ILAKFLHEL | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. | 登録日 | 2016-11-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
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8V30
| Smooth Muscle Gamma Actin (ACTG2) Filament Mutant R40C | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, gamma-enteric smooth muscle, ... | 著者 | Palmer, N.J, Carman, P.J, Ceron, R.H, Dominguez, R. | 登録日 | 2023-11-25 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy. Sci Adv, 10, 2024
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8V2O
| Cryo-EM Structure of Wildtype Smooth Muscle Gamma Actin (ACTG2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, gamma-enteric smooth muscle, ... | 著者 | Palmer, N.J, Carman, P.J, Ceron, R.H, Dominguez, R. | 登録日 | 2023-11-23 | 公開日 | 2024-05-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy. Sci Adv, 10, 2024
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2G7R
| X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 | 分子名称: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 著者 | Walker, J.R, Wybenga-Groot, L, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-02-28 | 公開日 | 2006-04-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | X-ray structure of the death domain of the human mucosa associated lymphoid tissue lymphoma translocation protein 1 To be Published
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5NBZ
| Wzz dodecamer fitted by MDFF to the Wzz experimental map from cryo-EM | 分子名称: | WzzB | 著者 | Ford, R.C, Kargas, V, Collins, R.F, Whitfield, C, Clarke, B.R, Siebert, A, Bond, P.J, Clare, D.K. | 登録日 | 2017-03-02 | 公開日 | 2017-04-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Full-length, Oligomeric Structure of Wzz Determined by Cryoelectron Microscopy Reveals Insights into Membrane-Bound States. Structure, 25, 2017
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2GC3
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5NHN
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5UM7
| Crystal structure of the reduced state of the thiol-disulfide reductase SdbA from Streptococcus gordonii | 分子名称: | ACETATE ION, Thioredoxin signature protein | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-01-26 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Crystal structure of the reduced state of the thiol-disulfide reductase SdbA from Streptococcus gordonii To Be Published
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5UWN
| Matrix metalloproteinase-13 complexed with selective inhibitor compound 10d | 分子名称: | CALCIUM ION, Collagenase 3, N-(2-aminoethyl)-4'-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)-[1,1'-biphenyl]-4-sulfonami de, ... | 著者 | Taylor, A.B, Cao, X, Hart, P.J. | 登録日 | 2017-02-21 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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5NMF
| 868 TCR in complex with HLA A02 presenting SLYNTIATL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2017-04-05 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
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2GC2
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5NQ1
| Porcine (Sus scrofa) Major Histocompatibility Complex, class I, with human beta2 micro globulin, presenting DFEREGYSL | 分子名称: | 1,2-ETHANEDIOL, ASP-PHE-GLU-ARG-GLU-GLY-TYR-SER-LEU, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Tungatt, K, Sewell, A.K. | 登録日 | 2017-04-19 | 公開日 | 2018-04-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
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4K1P
| Structure of the NheA component of the Nhe toxin from Bacillus cereus | 分子名称: | 1,2-ETHANEDIOL, NheA, SULFATE ION | 著者 | Ganash, M, Phung, D, Artymiuk, P.J. | 登録日 | 2013-04-05 | 公開日 | 2013-09-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of the NheA Component of the Nhe Toxin from Bacillus cereus: Implications for Function. Plos One, 8, 2013
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5XF6
| Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker | 分子名称: | DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ... | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | 登録日 | 2017-04-07 | 公開日 | 2017-10-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation Nat Commun, 8, 2017
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2GWF
| Structure of a USP8-NRDP1 complex | 分子名称: | RING finger protein 41, Ubiquitin carboxyl-terminal hydrolase 8 | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-05-04 | 公開日 | 2006-06-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281, 2006
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5XF4
| Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration) | 分子名称: | (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | 登録日 | 2017-04-07 | 公開日 | 2017-10-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation Nat Commun, 8, 2017
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2EUA
| Structure and Mechanism of MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia Coli | 分子名称: | D(-)-TARTARIC ACID, Menaquinone-specific isochorismate synthase | 著者 | Kolappan, S, Kisker, C, Zwahlen, J, Zhou, R, Tonge, P.J. | 登録日 | 2005-10-28 | 公開日 | 2006-12-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family. Biochemistry, 46, 2007
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5OJ3
| YCF48 from Cyanidioschyzon merolae | 分子名称: | Photosystem II stability/assembly factor HCF136 | 著者 | Michoux, F, Murray, J.W, Nixon, P.J. | 登録日 | 2017-07-20 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.982 Å) | 主引用文献 | Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II complex is a seven-bladed beta-propeller protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5UWM
| Matrix metalloproteinase-13 complexed with selective inhibitor compound (R)-17a | 分子名称: | (R)-N-(3-methyl-1-(methylamino)-1-oxobutan-2-yl)-5-(4-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)phenyl)furan-2-carboxamide, CALCIUM ION, Collagenase 3, ... | 著者 | Taylor, A.B, Cao, X, Hart, P.J. | 登録日 | 2017-02-21 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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5VBB
| Human RNA Pseudouridylate Synthase Domain Containing 1 | 分子名称: | CHLORIDE ION, GLYCEROL, RNA pseudouridylate synthase domain-containing protein 1, ... | 著者 | DONG, A, ZENG, H, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | 登録日 | 2017-03-29 | 公開日 | 2017-04-19 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Human RNA Pseudouridylate Synthase Domain Containing 1 to be published
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2F54
| Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity | 分子名称: | Beta-2-microglobulin, Cancer/testis antigen 1B, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M. | 登録日 | 2005-11-25 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Protein Sci., 15, 2006
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