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5N2L

Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue

Summary for 5N2L
Entry DOI10.2210/pdb5n2l/pdb
DescriptorBromodomain-containing protein 2, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordstranscription, structural genomics, structural genomics consortium, sgc
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight56020.31
Authors
Primary citationTallant, C.,Slavish, P.J.,Siejka, P.,Bharatham, N.,Shadrick, W.R.,Chai, S.,Young, B.M.,Boyd, V.A.,Heroven, C.,Wiggers, H.J.,Picaud, S.,Fedorov, O.,Krojer, T.,Chen, T.,Lee, R.E.,Guy, R.K.,Shelat, A.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.
Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.89 Å)
Structure validation

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PDB entries from 2024-03-27

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