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PDB: 2899 件

8T9N
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Bacillus subtilis RsgI GGG mutant
分子名称: Anti-sigma-I factor RsgI
著者Brogan, A.P, Habib, C, Hobbs, S.J, Kranzusch, P.J, Rudner, D.Z.
登録日2023-06-24
公開日2023-09-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bacterial SEAL domains undergo autoproteolysis and function in regulated intramembrane proteolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
4WST
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The crystal structure of hemagglutinin from A/Taiwan/1/2013 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Yang, H, Carney, P.J, Chang, J, Villanueva, J.M, Stevens, J.
登録日2014-10-28
公開日2015-02-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
4WSW
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The crystal structure of hemagglutinin from A/green-winged teal/Texas/Y171/2006 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
著者Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J.
登録日2014-10-28
公開日2015-02-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
4X0S
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Hexamer formed by a macrocycle containing a sequence from beta-2-microglobulin (63-69).
分子名称: CHLORIDE ION, ORN-TYR-LEU-LEU-PHI-TYR-VAL-GLU-ORN-LYS-VAL-ALA-MAA-ALA-VAL-LYS, SODIUM ION, ...
著者Spencer, R.K, Salveson, P.J, Nowick, J.S.
登録日2014-11-23
公開日2015-05-06
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献X-ray Crystallographic Structures of Oligomers of Peptides Derived from beta 2-Microglobulin.
J.Am.Chem.Soc., 137, 2015
2EUA
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Structure and Mechanism of MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia Coli
分子名称: D(-)-TARTARIC ACID, Menaquinone-specific isochorismate synthase
著者Kolappan, S, Kisker, C, Zwahlen, J, Zhou, R, Tonge, P.J.
登録日2005-10-28
公開日2006-12-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.
Biochemistry, 46, 2007
6ZRV
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93)
分子名称: Plasminogen activator inhibitor 1, VHH-s-a93 (Nb93)
著者Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2020-07-15
公開日2020-08-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity.
Int J Mol Sci, 21, 2020
7UCW
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Structure of mouse Decr1 in complex with 2'-5' oligoadenylate
分子名称: Decr1 protein, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
著者Govande, A.A, Kranzusch, P.J.
登録日2022-03-17
公開日2023-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献RNase L-activating 2'-5' oligoadenylates bind ABCF1, ABCF3 and Decr-1.
J.Gen.Virol., 104, 2023
4XCW
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Crystal structure of molybdenum cofactor biosynthesis protein MogA from Helicobacter pylori str. J99
分子名称: Molybdopterin adenylyltransferase
著者Stogios, P.J, Onopriyenko, O, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-12-18
公開日2015-02-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献To be published
To Be Published
8TTO
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Structure of Hachiman anti-defense 1 (Had1)
分子名称: Hachiman
著者Ragucci, A.E, Antine, S.P, Kranzusch, P.J.
登録日2023-08-14
公開日2023-11-22
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phages overcome bacterial immunity via diverse anti-defence proteins.
Nature, 625, 2024
7ROA
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Crystal structure of EntV136 from Enterococcus faecalis
分子名称: EntV
著者Stogios, P.J, Evdokimova, E, Kim, Y, Garsin, D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2021-07-30
公開日2022-10-12
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections.
Nat Commun, 13, 2022
4XA9
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Crystal structure of the complex between the N-terminal domain of RavJ and LegL1 from Legionella pneumophila str. Philadelphia
分子名称: Gala protein type 1, 3 or 4, Uncharacterized protein
著者Stogios, P.J, Cuff, M.E, Nocek, B, Evdokimova, E, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-12-13
公開日2015-01-28
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila.
Mol. Syst. Biol., 12, 2016
7TQN
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Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQQ
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Structure of human TREX1-DNA complex
分子名称: DNA (5'-D(P*TP*TP*GP*GP*CP*CP*GP*GP*CP*CP*AP*TP*C)-3'), Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQP
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Structure of human TREX1
分子名称: SULFATE ION, Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
7TQO
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Structure of human TREX1
分子名称: Three-prime repair exonuclease 1
著者Zhou, W, Richmond-Buccola, D, Kranzusch, P.J.
登録日2022-01-26
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun, 13, 2022
2CGT
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GROEL-ADP-gp31 COMPLEX
分子名称: 60 KDA GROEL, CAPSID ASSEMBLY PROTEIN GP31
著者Clare, D.K, Bakkes, P.J, van Heerikhuizen, H, van der Vies, S.M, Saibil, H.R.
登録日2006-03-09
公開日2006-03-29
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献An Expanded Protein Folding Cage in the Groel-Gp31 Complex.
J.Mol.Biol., 358, 2006
2CM7
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Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
分子名称: ISOTHIAZOLIDINONE ANALOG, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
著者Ala, P.J, Gonneville, L, Hillman, M.C, Becker-Pasha, M, Wei, M, Reid, B.G, Klabe, R, Yue, E.W, Wayland, B, Douty, B, Combs, A.P, Polam, P, Wasserman, Z, Bower, M, Burn, T.C, Hollis, G.F, Wynn, R.
登録日2006-05-04
公開日2006-08-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
J.Biol.Chem., 281, 2006
4XI1
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Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ...
著者Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-01-06
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.983 Å)
主引用文献Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
7SB8
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d(GA(CGA)5) parallel-stranded homo-duplex
分子名称: COBALT HEXAMMINE(III), GA(CGA)5, SODIUM ION, ...
著者Luteran, E.M, Paukstelis, P.J.
登録日2021-09-24
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.317 Å)
主引用文献The parallel-stranded d(CGA) duplex is a highly predictable structural motif with two conformationally distinct strands.
Acta Crystallogr D Struct Biol, 78, 2022
4XCX
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METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, Small RNA 2'-O-methyltransferase
著者Walker, J.R, Zeng, H, Dong, A, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
登録日2014-12-18
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal structure of human C1ORF59 in complex with SAH
To be published
2BOB
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Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA)
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ...
著者Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A.
登録日2005-04-09
公開日2005-04-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural Basis of Tea Blockade in a Model Potassium Channel
Nat.Struct.Mol.Biol., 12, 2005
8TJT
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The Fab fragment of an anti-glucagon receptor (GCGR) antibody
分子名称: anti-GCGR Fab heavy chain, anti-GCGR Fab light chain
著者Dai, J, Carter, P.J, Sudhamsu, J, Kung, J.
登録日2023-07-24
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody.
Mabs, 16, 2024
2CNI
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Structural Insights into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B
分子名称: MAGNESIUM ION, METHYL 2-{[5-({3-CHLORO-4-[(5S)-1,1-DIOXIDO-3-OXOISOTHIAZOLIDIN-5-YL]-N-(PHENYLSULFONYL)-L-PHENYLALANYL}AMINO)PENTYL]OXY}-6-HYDROXYBENZOATE, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
著者Ala, P.J, Gonneville, L, Hillman, M, Becker-Pasha, M, Yue, E.W, Douty, B, Wayland, B, Polam, P, Crawley, M.L, McLaughlin, E, Sparks, R.B, Glass, B, Takvorian, A, Combs, A.P, Burn, T.C, Hollis, G.F, Wynn, R.
登録日2006-05-21
公開日2006-09-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B.
J.Biol.Chem., 281, 2006
4Y1S
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Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
分子名称: CALCIUM ION, Perforin-1
著者Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S.
登録日2015-02-09
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.611 Å)
主引用文献Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290, 2015
2CMB
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Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics
分子名称: N-{[4-(1,1-DIOXIDO-3-OXO-2,3-DIHYDROISOTHIAZOL-5-YL)PHENYL]ACETYL}-L-PHENYLALANYL-4-(1,1-DIOXIDO-3-OXO-2,3-DIHYDROISOTHIAZOL-5-YL)-L-PHENYLALANINAMIDE, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1, octyl beta-D-glucopyranoside
著者Ala, P.J, Gonneville, L, Hillman, M.C, Becker-Pasha, M, Wei, M, Reid, B.G, Klabe, R, Yue, E.W, Wayland, B, Douty, B, Combs, A.P, Polam, P, Wasserman, Z, Bower, M, Burn, T.C, Hollis, G.F, Wynn, R.
登録日2006-05-04
公開日2006-08-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for Inhibition of Protein-Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics.
J.Biol.Chem., 281, 2006

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