4C33
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![BU of 4c33 by Molmil](/molmil-images/mine/4c33) | PKA-S6K1 Chimera Apo | Descriptor: | CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA | Authors: | Couty, S, Westwood, I.M, Kalusa, A, Cano, C, Travers, J, Boxall, K, Chow, C.L, Burns, S, Schmitt, J, Pickard, L, Barillari, C, McAndrew, P.C, Clarke, P.A, Linardopoulos, S, Griffin, R.J, Aherne, G.W, Raynaud, F.I, Workman, P, Jones, K, van Montfort, R.L.M. | Deposit date: | 2013-08-21 | Release date: | 2013-10-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design. Oncotarget, 4, 2013
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2QLW
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![BU of 2qlw by Molmil](/molmil-images/mine/2qlw) | |
2QYQ
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2L37
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![BU of 2l37 by Molmil](/molmil-images/mine/2l37) | 3D solution structure of arginine/glutamate-rich polypeptide Luffin P1 from the seeds of sponge gourd (Luffa cylindrical) | Descriptor: | Ribosome-inactivating protein luffin P1 | Authors: | Ng, Y.M, Yang, Y, Sze, K.H, Zhang, X, Zheng, Y.T, Shaw, P.C. | Deposit date: | 2010-09-08 | Release date: | 2011-01-19 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structural characterization and anti-HIV-1 activities of arginine/glutamate-rich polypeptide Luffin P1 from the seeds of sponge gourd (Luffa cylindrical). J.Struct.Biol., 2010
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2R4S
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![BU of 2r4s by Molmil](/molmil-images/mine/2r4s) | Crystal structure of the human beta2 adrenoceptor | Descriptor: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | Authors: | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | Deposit date: | 2007-08-31 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature, 450, 2007
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4A6Z
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![BU of 4a6z by Molmil](/molmil-images/mine/4a6z) | Cytochrome c peroxidase with bound guaiacol | Descriptor: | CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, Guaiacol, ... | Authors: | Murphy, E.J, Metcalfe, C.L, Nnamchi, C, Raven, E.L, Moody, P.C.E. | Deposit date: | 2011-11-10 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Crystal Structure of Guaiacol and Phenol Bound to a Heme Peroxidase. FEBS J., 279, 2012
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4A7M
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![BU of 4a7m by Molmil](/molmil-images/mine/4a7m) | cytochrome c peroxidase S81W mutant | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, ... | Authors: | Murphy, E.J, Metcalfe, C.L, Raven, E.L, Moody, P.C.E. | Deposit date: | 2011-11-14 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Crystal Structure of Guaiacol and Phenol Bound to a Heme Peroxidase. FEBS J., 279, 2012
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4B9K
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![BU of 4b9k by Molmil](/molmil-images/mine/4b9k) | pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound | Descriptor: | (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | Authors: | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | Deposit date: | 2012-09-05 | Release date: | 2012-10-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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2R4R
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![BU of 2r4r by Molmil](/molmil-images/mine/2r4r) | Crystal structure of the human beta2 adrenoceptor | Descriptor: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | Authors: | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | Deposit date: | 2007-08-31 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature, 450, 2007
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4AMI
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![BU of 4ami by Molmil](/molmil-images/mine/4ami) | Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist bucindolol | Descriptor: | 2-[(2S)-3-[[1-(1H-indol-3-yl)-2-methyl-propan-2-yl]amino]-2-oxidanyl-propoxy]benzenecarbonitrile, BETA-1 ADRENERGIC RECEPTOR, HEGA-10 | Authors: | Warne, T, Edwards, P.C, Leslie, A.G, Tate, C.G. | Deposit date: | 2012-03-11 | Release date: | 2012-05-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structures of a Stabilized Beta1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol Structure, 20, 2012
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2REA
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4CSY
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![BU of 4csy by Molmil](/molmil-images/mine/4csy) | E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, E-SELECTIN, ... | Authors: | Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T. | Deposit date: | 2014-03-11 | Release date: | 2014-09-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation. J.Mol.Cell.Biol., 8, 2016
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2MIP
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![BU of 2mip by Molmil](/molmil-images/mine/2mip) | CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 2 PROTEASE IN COMPLEX WITH A REDUCED AMIDE INHIBITOR AND COMPARISON WITH HIV-1 PROTEASE STRUCTURES | Descriptor: | HIV-2 PROTEASE, INHIBITOR BI-LA-398 | Authors: | Tong, L, Pav, S, Pargellis, C, Do, F, Lamarre, D, Anderson, P.C. | Deposit date: | 1993-06-03 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. Proc.Natl.Acad.Sci.USA, 90, 1993
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4BVN
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![BU of 4bvn by Molmil](/molmil-images/mine/4bvn) | Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, ... | Authors: | Miller, J, Nehme, R, Warne, T, Edwards, P.C, Leslie, A.G.W, Schertler, G, Tate, C.G. | Deposit date: | 2013-06-26 | Release date: | 2014-04-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor. Plos One, 9, 2014
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2RED
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![BU of 2red by Molmil](/molmil-images/mine/2red) | Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding. | Descriptor: | GLYCEROL, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide | Authors: | Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S. | Deposit date: | 2007-09-26 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding Bmc Struct.Biol., 8, 2008
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2MMX
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2UWH
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![BU of 2uwh by Molmil](/molmil-images/mine/2uwh) | Cytochrome P450 BM3 mutant in complex with palmitic acid | Descriptor: | BIFUNCTIONAL P-450: NADPH-P450 REDUCTASE, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Huang, W.-C, Joyce, M.G, Westlake, A.C.G, Roberts, G.C.K, Moody, P.C.E. | Deposit date: | 2007-03-21 | Release date: | 2007-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Filling a Hole in Cytochrome P450 Bm3 Improves Substrate Binding and Catalytic Efficiency. J.Mol.Biol., 373, 2007
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4AMJ
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![BU of 4amj by Molmil](/molmil-images/mine/4amj) | Turkey beta1 adrenergic receptor with stabilising mutations and bound biased agonist carvedilol | Descriptor: | (2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL, BETA-1 ADRENERGIC RECEPTOR, HEGA-10, ... | Authors: | Warne, T, Edwards, P.C, Leslie, A.G, Tate, C.G. | Deposit date: | 2012-03-12 | Release date: | 2012-05-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of a Stabilized Beta1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol Structure, 20, 2012
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4A7W
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![BU of 4a7w by Molmil](/molmil-images/mine/4a7w) | Crystal structure of uridylate kinase from Helicobacter pylori | Descriptor: | GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, URIDYLATE KINASE | Authors: | Chu, C.H, Chen, P.C, Liu, M.H, Sun, Y.J. | Deposit date: | 2011-11-15 | Release date: | 2012-06-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of Helicobacter Pylori Uridylate Kinase: Insight Into Release of the Product Udp Acta Crystallogr.,Sect.D, 68, 2012
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2JDL
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![BU of 2jdl by Molmil](/molmil-images/mine/2jdl) | Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin | Descriptor: | ACIDIC RIBOSOMAL PROTEIN P2, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN | Authors: | Too, P.H, Mak, A.N, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C. | Deposit date: | 2007-01-11 | Release date: | 2008-02-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome. Nucleic Acids Res., 37, 2009
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2JJR
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![BU of 2jjr by Molmil](/molmil-images/mine/2jjr) | V232K, N236D-trichosanthin | Descriptor: | DI(HYDROXYETHYL)ETHER, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN, SULFATE ION, ... | Authors: | Too, P.H, Ma, M.K, Mak, A.N, Tung, C.K, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C. | Deposit date: | 2008-04-21 | Release date: | 2008-12-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome. Nucleic Acids Res., 37, 2009
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2VEW
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![BU of 2vew by Molmil](/molmil-images/mine/2vew) | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B IN COMPLEX WITH AN ISOTHIAZOLIDINONE-CONTAINING INHIBITOR | Descriptor: | 3-fluoro-N-[(1S)-1-[4-[(2-fluorophenyl)methyl]imidazol-2-yl]-2-[4-[(5S)-1,1,3-trioxo-1,2-thiazolidin-5-yl]phenyl]ethyl]benzenesulfonamide, MAGNESIUM ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | Authors: | Douty, B, Wayland, B, Ala, P.J, Bower, M.J, Pruitt, J, Bostrom, L, Wei, M, Klabe, R, Gonneville, L, Wynn, R, Burn, T.C, Liu, P.C.C, Combs, A.P, Yue, E.W. | Deposit date: | 2007-10-27 | Release date: | 2007-11-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Isothiazolidinone Inhibitors of Ptp1B Containing Imidazoles and Imidazolines Bioorg.Med.Chem.Lett., 18, 2008
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4A78
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![BU of 4a78 by Molmil](/molmil-images/mine/4a78) | cytochrome c peroxidase M119W in complex with guiacol | Descriptor: | CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, Guaiacol, ... | Authors: | Murphy, E.J, Metcalfe, C.L, Raven, E.L, Moody, P.C.E. | Deposit date: | 2011-11-11 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of Guaiacol and Phenol Bound to a Heme Peroxidase. FEBS J., 279, 2012
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2V23
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![BU of 2v23 by Molmil](/molmil-images/mine/2v23) | Structure of cytochrome c peroxidase mutant N184R Y36A | Descriptor: | CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Metcalfe, C.L, Macdonald, I.K, Brown, K.A, Raven, E.L, Moody, P.C.E. | Deposit date: | 2007-05-31 | Release date: | 2007-12-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases. J.Biol.Chem., 283, 2008
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2JP0
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![BU of 2jp0 by Molmil](/molmil-images/mine/2jp0) | Solution structure of the N-terminal extraceullular domain of the lymphocyte receptor CD5 calculated using inferential structure determination (ISD) | Descriptor: | T-cell surface glycoprotein CD5 | Authors: | Garza-Garcia, A, Harris, R, Esposito, D, Driscoll, P.C, Rieping, W. | Deposit date: | 2007-04-16 | Release date: | 2008-02-26 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5 J.Mol.Biol., 378, 2008
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