4BVN

Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound

Summary for 4BVN

DescriptorBETA-1 ADRENERGIC RECEPTOR, SODIUM ION, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, ... (6 entities in total)
Functional Keywordssignaling protein
Biological sourceMELEAGRIS GALLOPAVO (TURKEY)
Total number of polymer chains1
Total molecular weight38910.1
Authors
Miller, J.,Nehme, R.,Warne, T.,Edwards, P.C.,Leslie, A.G.W.,Schertler, G.,Tate, C.G. (deposition date: 2013-06-26, release date: 2014-04-02, Last modification date: 2019-03-06)
Primary citation
Miller-Gallacher, J.L.,Nehme, R.,Warne, T.,Edwards, P.C.,Schertler, G.F.X.,Leslie, A.G.W.,Tate, C.G.
The 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor.
Plos One, 9:92727-, 2014
PubMed: 24663151 (PDB entries with the same primary citation)
DOI: 10.1371/JOURNAL.PONE.0092727
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24740 0.8% 6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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