Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004935 | molecular_function | adrenergic receptor activity |
| A | 0004940 | molecular_function | beta1-adrenergic receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0007189 | biological_process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0045823 | biological_process | positive regulation of heart contraction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1359 |
| Chain | Residue |
| A | ASP87 |
| A | SER128 |
| A | HOH3005 |
| A | HOH3006 |
| A | HOH3032 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1360 |
| Chain | Residue |
| A | HOH3021 |
| A | CYS192 |
| A | ASP195 |
| A | CYS198 |
| A | HOH3013 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE OLC A 2001 |
| Chain | Residue |
| A | VAL172 |
| A | PRO176 |
| A | TRP181 |
| A | ARG183 |
| A | ARG205 |
| A | ILE209 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OLC A 2002 |
| Chain | Residue |
| A | TRP107 |
| A | LEU108 |
| A | TRP109 |
| A | ASP195 |
| A | GLY197 |
| A | TYR231 |
| A | LYS287 |
| A | LYS290 |
| A | GLY293 |
| A | MHA1362 |
| A | OLC2003 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OLC A 2003 |
| Chain | Residue |
| A | ALA227 |
| A | TYR231 |
| A | HIS286 |
| A | LYS287 |
| A | LEU289 |
| A | MET296 |
| A | OLC2002 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE OLC A 2004 |
| Chain | Residue |
| A | LYS322 |
| A | VAL326 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE OLC A 2005 |
| Chain | Residue |
| A | TYR140 |
| A | TYR140 |
| A | ARG157 |
| A | ARG157 |
| A | OLC2006 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE OLC A 2006 |
| Chain | Residue |
| A | ILE137 |
| A | ILE137 |
| A | ASP138 |
| A | PHE225 |
| A | OLC2005 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE OLC A 2007 |
| Chain | Residue |
| A | THR74 |
| A | LEU75 |
| A | ARG139 |
| A | ALA142 |
| A | ILE143 |
| A | TYR149 |
| A | GLU285 |
| A | LEU289 |
| site_id | BC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE P32 A 1361 |
| Chain | Residue |
| A | TRP117 |
| A | ASP121 |
| A | VAL122 |
| A | THR203 |
| A | ALA208 |
| A | SER211 |
| A | SER215 |
| A | TRP303 |
| A | PHE306 |
| A | PHE307 |
| A | ASN310 |
| A | ASN329 |
| A | TYR333 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MHA A 1362 |
| Chain | Residue |
| A | GLY110 |
| A | SER111 |
| A | PRO196 |
| A | LYS287 |
| A | LYS290 |
| A | THR291 |
| A | ARG345 |
| A | SER346 |
| A | OLC2002 |
| A | HOH3011 |
| A | HOH3038 |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASVeTLCVIAIDRYLaI |
| Chain | Residue | Details |
| A | ALA127-ILE143 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Transmembrane: {"description":"Helical; Name=1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"18594507","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 26 |
| Details | Transmembrane: {"description":"Helical; Name=2"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"18594507","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=3"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=4"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=5"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 29 |
| Details | Transmembrane: {"description":"Helical; Name=6"} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical; Name=7"} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18594507","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VT4","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
