7A7B
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![BU of 7a7b by Molmil](/molmil-images/mine/7a7b) | Bacillithiol Disulfide Reductase Bdr (YpdA) from Staphylococcus aureus | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, YpdA family putative bacillithiol disulfide reductase Bdr | Authors: | Hammerstad, M, Hersleth, H.-P. | Deposit date: | 2020-08-27 | Release date: | 2020-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Crystal Structures of Bacillithiol Disulfide Reductase Bdr (YpdA) Provide Structural and Functional Insight into a New Type of FAD-Containing NADPH-Dependent Oxidoreductase. Biochemistry, 59, 2020
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7R49
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![BU of 7r49 by Molmil](/molmil-images/mine/7r49) | Crystal structure of the L. plantarum acyl carrier protein synthase (AcpS)in complex with D-alanyl carrier protein (DltC1) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4'-PHOSPHOPANTETHEINE, D-alanyl carrier protein 1, ... | Authors: | Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C. | Deposit date: | 2022-02-08 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum. Sci Rep, 12, 2022
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1AM4
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![BU of 1am4 by Molmil](/molmil-images/mine/1am4) | COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) | Descriptor: | CDC42HS, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 1997-06-22 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature, 388, 1997
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7MDO
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![BU of 7mdo by Molmil](/molmil-images/mine/7mdo) | Structure of human p97 ATPase L464P mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | Deposit date: | 2021-04-05 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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7MDM
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![BU of 7mdm by Molmil](/molmil-images/mine/7mdm) | Structure of human p97 ATPase L464P mutant | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. | Deposit date: | 2021-04-05 | Release date: | 2021-08-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.86 Å) | Cite: | Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
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5KMM
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![BU of 5kmm by Molmil](/molmil-images/mine/5kmm) | TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(1-naphthyl)urea | Descriptor: | 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-naphthalen-1-yl-urea, High affinity nerve growth factor receptor | Authors: | Su, H.P. | Deposit date: | 2016-06-27 | Release date: | 2016-12-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8OM2
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![BU of 8om2 by Molmil](/molmil-images/mine/8om2) | Small subunit of yeast mitochondrial ribosome in complex with METTL17/Rsm22. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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1AJR
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![BU of 1ajr by Molmil](/molmil-images/mine/1ajr) | REFINEMENT AND COMPARISON OF THE CRYSTAL STRUCTURES OF PIG CYTOSOLIC ASPARTATE AMINOTRANSFERASE AND ITS COMPLEX WITH 2-METHYLASPARTATE | Descriptor: | ASPARTATE AMINOTRANSFERASE | Authors: | Rhee, S, Silva, M.M, Hyde, C.C, Rogers, P.H, Metzler, C.M, Metzler, D.E, Arnone, A. | Deposit date: | 1997-05-08 | Release date: | 1997-08-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Refinement and comparisons of the crystal structures of pig cytosolic aspartate aminotransferase and its complex with 2-methylaspartate. J.Biol.Chem., 272, 1997
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7RT7
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![BU of 7rt7 by Molmil](/molmil-images/mine/7rt7) | Crystal structure of the RhsP2 C-terminal toxin domain in complex with its immunity protein, RhsI2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhsI2, RhsP2 | Authors: | Bullen, N.P, Prehna, G, Whitney, J.C. | Deposit date: | 2021-08-12 | Release date: | 2022-08-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs. Mol.Cell, 82, 2022
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8OM4
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![BU of 8om4 by Molmil](/molmil-images/mine/8om4) | Small subunit of yeast mitochondrial ribosome. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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8OM3
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![BU of 8om3 by Molmil](/molmil-images/mine/8om3) | Small subunit of yeast mitochondrial ribosome in complex with IF3/Aim23. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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8BVI
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![BU of 8bvi by Molmil](/molmil-images/mine/8bvi) | |
6L6Y
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![BU of 6l6y by Molmil](/molmil-images/mine/6l6y) | |
6UAR
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![BU of 6uar by Molmil](/molmil-images/mine/6uar) | Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose | Descriptor: | Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | Authors: | Costa, P.A.C.R, Santos, C.R, Murakami, M.T. | Deposit date: | 2019-09-11 | Release date: | 2020-05-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
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6UAU
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![BU of 6uau by Molmil](/molmil-images/mine/6uau) | Crystal structure of a GH128 (subgroup I) endo-beta-1,3-glucanase (E102A mutant) from Amycolatopsis mediterranei (AmGH128_I) in complex with laminaritriose and laminaribiose | Descriptor: | DI(HYDROXYETHYL)ETHER, Glyco_hydro_cc domain-containing protein, ZINC ION, ... | Authors: | Vieira, P.S, Cabral, L, Costa, P.A.C.R, Santos, C.R, Murakami, M.T. | Deposit date: | 2019-09-11 | Release date: | 2020-05-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
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6UB0
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![BU of 6ub0 by Molmil](/molmil-images/mine/6ub0) | Crystal structure of a GH128 (subgroup III) curdlan-specific exo-beta-1,3-glucanase from Blastomyces gilchristii (BgGH128_III) in complex with laminaribiose at -2 and -1 subsites | Descriptor: | Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose | Authors: | Costa, P.A.C.R, Santos, C.R, Domingues, M.N, Lima, E.A, Mandelli, F, Murakami, M.T. | Deposit date: | 2019-09-11 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
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3HOW
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![BU of 3how by Molmil](/molmil-images/mine/3how) | Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | Descriptor: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | Deposit date: | 2009-06-03 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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5KMJ
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![BU of 5kmj by Molmil](/molmil-images/mine/5kmj) | TrkA JM-kinase with {N}-(2-pyridylmethyl)-2-[2-(2-thienyl)indol-1-yl]acetamide | Descriptor: | High affinity nerve growth factor receptor, ~{N}-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)ethanamide | Authors: | Su, H.P. | Deposit date: | 2016-06-27 | Release date: | 2016-12-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5HL0
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![BU of 5hl0 by Molmil](/molmil-images/mine/5hl0) | Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (54-60, pY55) Refined to 2.2A Resolution | Descriptor: | E3 ubiquitin-protein ligase CBL, SODIUM ION, Sprouty 2 (SPRY2) | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, Zhang, N, Cooper, A, Gao, P, Perez, R.P. | Deposit date: | 2016-01-14 | Release date: | 2017-01-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of c-Cbl TKBD in complex with SPRY2 peptide (54-60, pY55) Refined to 2.2A Resolution To Be Published
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6UBB
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![BU of 6ubb by Molmil](/molmil-images/mine/6ubb) | Crystal structure of a GH128 (subgroup VI) exo-beta-1,3-glucanase from Aureobasidium namibiae (AnGH128_VI) with laminaribiose at the surface-binding site | Descriptor: | Glyco_hydro_cc domain-containing protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | Authors: | Santos, C.R, Vieira, P.S, Domingues, M.N, Cordeiro, R.L, Tomazini, A, Murakami, M.T. | Deposit date: | 2019-09-11 | Release date: | 2020-05-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into beta-1,3-glucan cleavage by a glycoside hydrolase family. Nat.Chem.Biol., 16, 2020
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6RAW
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![BU of 6raw by Molmil](/molmil-images/mine/6raw) | D. melanogaster CMG-DNA, State 1A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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7Z43
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![BU of 7z43 by Molmil](/molmil-images/mine/7z43) | |
7A60
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![BU of 7a60 by Molmil](/molmil-images/mine/7a60) | Crystal structure of VIM-2 with hydrolyzed faropenem (ring-open form) | Descriptor: | (5~{Z})-2-[1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-(4-oxidanylbutylidene)-2~{H}-1,3-thiazole-4-carboxylic acid, Beta-lactamase VIM-2, FORMIC ACID, ... | Authors: | Hinchliffe, P, Spencer, J. | Deposit date: | 2020-08-24 | Release date: | 2021-02-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Faropenem reacts with serine and metallo-beta-lactamases to give multiple products. Eur.J.Med.Chem., 215, 2021
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7Z42
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![BU of 7z42 by Molmil](/molmil-images/mine/7z42) | |
7A61
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![BU of 7a61 by Molmil](/molmil-images/mine/7a61) | Crystal structure of KPC-2 with hydrolyzed faropenem (ring-open form) | Descriptor: | (2~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-butyl-2,3-dihydro-1,3-thiazole-4-carboxylic acid, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, ... | Authors: | Tooke, C.L, Hinchliffe, P, Spencer, J. | Deposit date: | 2020-08-24 | Release date: | 2021-02-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Faropenem reacts with serine and metallo-beta-lactamases to give multiple products. Eur.J.Med.Chem., 215, 2021
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