2A21
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![BU of 2a21 by Molmil](/molmil-images/mine/2a21) | Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+ | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, PHOSPHOENOLPYRUVATE, ... | Authors: | Kona, F, Xu, X, Lu, J, Martin, P, Gatti, D.L. | Deposit date: | 2005-06-21 | Release date: | 2006-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
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4U0P
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![BU of 4u0p by Molmil](/molmil-images/mine/4u0p) | The Crystal Structure of Lipoyl Synthase in Complex with S-Adenosyl Homocysteine | Descriptor: | IRON/SULFUR CLUSTER, Lipoyl synthase 2, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Harmer, J.E, Hiscox, M.J, Sandy, J, Dinis, P.C, Roach, P.L. | Deposit date: | 2014-07-13 | Release date: | 2014-08-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.623 Å) | Cite: | Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions. Biochem.J., 464, 2014
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5R4W
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![BU of 5r4w by Molmil](/molmil-images/mine/5r4w) | XChem fragment screen -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF THE HUMAN ATAD2 in complex with N13501a | Descriptor: | 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, SULFATE ION, ... | Authors: | Talon, R, Krojer, T, Fairhead, M, Sethi, R, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Wright, N, MacLean, E, Zhang, R, Dias, A, Brennan, P.E, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2020-02-28 | Release date: | 2020-05-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | XChem fragment screen To Be Published
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4B16
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![BU of 4b16 by Molmil](/molmil-images/mine/4b16) | |
1L3C
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![BU of 1l3c by Molmil](/molmil-images/mine/1l3c) | MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, C2 SPACEGROUP WITH SHORT CELL | Descriptor: | Precorrin-6y methyltransferase/putative decarboxylase | Authors: | Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F. | Deposit date: | 2002-02-26 | Release date: | 2002-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | The Crystal Structure of Mt0146/Cbit Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase Structure, 10, 2002
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4AVB
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![BU of 4avb by Molmil](/molmil-images/mine/4avb) | Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | Authors: | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | Deposit date: | 2012-05-24 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis. Nat.Struct.Mol.Biol., 19, 2012
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1QHJ
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![BU of 1qhj by Molmil](/molmil-images/mine/1qhj) | X-RAY STRUCTURE OF BACTERIORHODOPSIN GROWN IN LIPIDIC CUBIC PHASES | Descriptor: | 1,2-[DI-2,6,10,14-TETRAMETHYL-HEXADECAN-16-OXY]-PROPANE, PROTEIN (BACTERIORHODOPSIN), RETINAL | Authors: | Belrhali, H, Nollert, P, Royant, A, Menzel, C, Rosenbusch, J.P, Landau, E.M, Pebay-Peyroula, E. | Deposit date: | 1999-05-04 | Release date: | 1999-07-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Protein, lipid and water organization in bacteriorhodopsin crystals: a molecular view of the purple membrane at 1.9 A resolution. Structure Fold.Des., 7, 1999
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1QWS
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![BU of 1qws by Molmil](/molmil-images/mine/1qws) | Structure of the D181N variant of catalase HPII from E. coli | Descriptor: | Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chelikani, P, Carpena, X, Fita, I, Loewen, P.C. | Deposit date: | 2003-09-03 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | An electrical potential in the access channel of catalases enhances catalysis J.Biol.Chem., 278, 2003
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2QWS
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![BU of 2qws by Molmil](/molmil-images/mine/2qws) | |
4F03
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![BU of 4f03 by Molmil](/molmil-images/mine/4f03) | |
1QLD
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![BU of 1qld by Molmil](/molmil-images/mine/1qld) | |
5UZU
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![BU of 5uzu by Molmil](/molmil-images/mine/5uzu) | Immune evasion by a Staphylococcal Peroxidase Inhibitor that blocks myeloperoxidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | de Jong, N, Geisbrecht, B.V, van Strijp, J, Haas, P, Nijland, R, Ramyar, K, Fevre, C, Guerra, F, Voyich-Kane, J, van Kessel, C, Garcia, B. | Deposit date: | 2017-02-27 | Release date: | 2017-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Immune evasion by a staphylococcal inhibitor of myeloperoxidase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4B8V
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![BU of 4b8v by Molmil](/molmil-images/mine/4b8v) | Cladosporium fulvum LysM effector Ecp6 in complex with a beta-1,4- linked N-acetyl-D-glucosamine tetramer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | Authors: | Saleem-Batcha, R, Sanchez-Vallet, A, Hansen, G, Thomma, B.P.H.J, Mesters, J.R. | Deposit date: | 2012-08-30 | Release date: | 2013-07-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Fungal Effector Ecp6 Outcompetes Host Immune Receptor for Chitin Binding Through Intrachain Lysm Dimerization Elife, 2, 2013
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1QD9
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![BU of 1qd9 by Molmil](/molmil-images/mine/1qd9) | Bacillus subtilis YABJ | Descriptor: | ACETIC ACID, ETHYL MERCURY ION, MERCURY (II) ION, ... | Authors: | Smith, J.L, Sinha, S, Rappu, P, Lange, S.C, Mantsala, P, Zalkin, H. | Deposit date: | 1999-07-09 | Release date: | 1999-11-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family. Proc.Natl.Acad.Sci.USA, 96, 1999
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2ORL
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![BU of 2orl by Molmil](/molmil-images/mine/2orl) | Solution structure of the cytochrome c- para-aminophenol adduct | Descriptor: | 4-AMINOPHENOL, Cytochrome c iso-1, HEME C | Authors: | Assfalg, M, Bertini, I, Del Conte, R, Giachetti, A, Turano, P. | Deposit date: | 2007-02-03 | Release date: | 2007-04-24 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Cytochrome c and organic molecules: solution structure of the p-aminophenol adduct. Biochemistry, 46, 2007
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3G9E
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![BU of 3g9e by Molmil](/molmil-images/mine/3g9e) | Aleglitaar. a new. potent, and balanced dual ppara/g agonist for the treatment of type II diabetes | Descriptor: | (2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | Authors: | Ruf, A, Benz, J, Bernardeau, A, Binggeli, A, Blum, D, Boehringer, M, Grether, U, Hilpert, H, Kuhn, B, Maerki, H.P, Meyer, M, Puenterner, K, Raab, S, Schlatter, D, Gsell, B, Stihle, M, Mohr, P. | Deposit date: | 2009-02-13 | Release date: | 2009-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes. Bioorg.Med.Chem.Lett., 19, 2009
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2OWI
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![BU of 2owi by Molmil](/molmil-images/mine/2owi) | Solution structure of the RGS domain from human RGS18 | Descriptor: | Regulator of G-protein signaling 18 | Authors: | Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-16 | Release date: | 2007-02-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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5UVD
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![BU of 5uvd by Molmil](/molmil-images/mine/5uvd) | Crystal structure of an antigenic nucleotidyltransferase-like protein from Paracoccidioides brasiliensis | Descriptor: | MAGNESIUM ION, Nucleotidyltransferase-like protein | Authors: | Nagem, R.A.P, Costa, M.A.F, Rodrigues, F.T.G, Coitinho, J.B.C. | Deposit date: | 2017-02-20 | Release date: | 2018-01-31 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis. Mol.Immunol., 112, 2019
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2GL1
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![BU of 2gl1 by Molmil](/molmil-images/mine/2gl1) | NMR solution structure of Vigna radiata Defensin 2 (VrD2) | Descriptor: | PDF1 | Authors: | Lin, K.F, Lee, T.R, Tsai, P.H, Hsu, M.P, Chen, C.S, Lyu, P.C. | Deposit date: | 2006-04-04 | Release date: | 2007-04-03 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure-based protein engineering for alpha-amylase inhibitory activity of plant defensin. Proteins, 68, 2007
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2AEC
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![BU of 2aec by Molmil](/molmil-images/mine/2aec) | Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,6-Man-beta-OR | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, ... | Authors: | Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K. | Deposit date: | 2005-07-22 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol., 353, 2005
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4D6O
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![BU of 4d6o by Molmil](/molmil-images/mine/4d6o) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MG (STATE 2) | Descriptor: | 25MER, ACETATE ION, HOMING ENDONUCLEASE I-DMOI, ... | Authors: | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | Deposit date: | 2014-11-13 | Release date: | 2014-12-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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1ND7
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![BU of 1nd7 by Molmil](/molmil-images/mine/1nd7) | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase | Descriptor: | WW domain-containing protein 1 | Authors: | Verdecia, M.A, Joaziero, C.A.P, Wells, N.J, Ferrer, J.-L, Bowman, M.E, Hunter, T, Noel, J.P. | Deposit date: | 2002-12-08 | Release date: | 2003-09-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase Mol.Cell, 11, 2003
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2Q5A
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![BU of 2q5a by Molmil](/molmil-images/mine/2q5a) | human Pin1 bound to L-PEPTIDE | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE, Five residue peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Noel, J.P, Zhang, Y. | Deposit date: | 2007-05-31 | Release date: | 2007-06-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chem.Biol., 2, 2007
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1ZXG
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![BU of 1zxg by Molmil](/molmil-images/mine/1zxg) | Solution structure of A219 | Descriptor: | Immunoglobulin G binding protein A | Authors: | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | Deposit date: | 2005-06-08 | Release date: | 2005-11-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds. Biochemistry, 44, 2005
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1N8J
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![BU of 1n8j by Molmil](/molmil-images/mine/1n8j) | |