2OWI

Solution structure of the RGS domain from human RGS18

Replaces:  2H33

Summary for 2OWI

• Entry DOI: 10.2210/pdb2owi/pdb
• Related: 2JM5
• NMR Information: BMRB: 7106
• Descriptor: Regulator of G-protein signaling 18 (1 entity in total)
• Functional Keywords: signaling protein, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q9NS28
• Total number of polymer chains: 1
• Total formula weight: 17786.02

Authors

Higman, V.A.,Leidert, M.,Bray, J.,Elkins, J.,Soundararajan, M.,Doyle, D.A.,Gileadi, C.,Phillips, C.,Schoch, G.,Yang, X.,Brockmann, C.,Schmieder, P.,Diehl, A.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Oschkinat, H.,Ball, L.J.,Structural Genomics Consortium (SGC) (deposition date: 2007-02-16, release date: 2007-02-27, Last modification date: 2012-08-15)

• Primary citation: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

Experimental method

SOLUTION NMR