2NY3
 
 | | HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | Authors: | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | | Deposit date: | 2006-11-20 | | Release date: | 2007-02-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
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1Z1Y
 | | Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax | | Descriptor: | YTTERBIUM (III) ION, ookinete surface protein Pvs25 | | Authors: | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | Deposit date: | 2005-03-07 | | Release date: | 2005-12-06 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
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4IGR
 | | Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist ZA302 | | Descriptor: | (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid, CHLORIDE ION, Glutamate receptor, ... | | Authors: | Larsen, A.P, Venskutonyte, R, Gajhede, M, Kastrup, J.S, Frydenvang, K. | | Deposit date: | 2012-12-18 | | Release date: | 2013-03-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
J.Med.Chem., 56, 2013
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1UZ8
 | | anti-Lewis X Fab fragment in complex with Lewis X | | Descriptor: | IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A, KAPPA) LIGHT CHAIN 291-2G3-A, ... | | Authors: | Van Roon, A.M.M, Pannu, N.S, De Vrind, J.P.M, Hokke, C.H, Deelder, A.M, Van Der marel, G.A, Van Boom, J.H, Abrahams, J.P. | | Deposit date: | 2004-03-05 | | Release date: | 2004-06-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen
Structure, 12, 2004
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1Z2Q
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5OJ4
 | | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) D182A variant in complex with mannosylglycerate | | Descriptor: | (2R)-3-hydroxy-2-(alpha-D-mannopyranosyloxy)propanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | | Deposit date: | 2017-07-20 | | Release date: | 2018-08-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
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5OJU
 | | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with glucosylglycerate | | Descriptor: | (2R)-2-(alpha-D-glucopyranosyloxy)-3-hydroxypropanoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | | Deposit date: | 2017-07-24 | | Release date: | 2018-08-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
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2GYX
 | | Crystal structure of DB884- D(CGCGAATTCGCG)2 complex at 1.86 A resolution. | | Descriptor: | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, N,N'-(1H-PYRROLE-2,5-DIYLDI-4,1-PHENYLENE)DIBENZENECARBOXIMIDAMIDE | | Authors: | Lee, M.P.H, Neidle, S. | | Deposit date: | 2006-05-10 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex.
J.Am.Chem.Soc., 129, 2007
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4IJD
 | | Crystal structure of methyltransferase domain of human PR domain-containing protein 9 | | Descriptor: | Histone-lysine N-methyltransferase PRDM9, UNKNOWN ATOM OR ION, ZINC ION | | Authors: | Dong, A, Dombrovski, L, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2012-12-21 | | Release date: | 2013-02-13 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of methyltransferase domain of human PR domain-containing protein 9
To be Published
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3KG2
 | | AMPA subtype ionotropic glutamate receptor in complex with competitive antagonist ZK 200775 | | Descriptor: | Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Sobolevsky, A.I, Rosconi, M.P, Gouaux, E. | | Deposit date: | 2009-10-28 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor.
Nature, 462, 2009
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2ZVS
 | | Crystal structure of the 2[4FE-4S] ferredoxin from escherichia coli | | Descriptor: | IRON/SULFUR CLUSTER, Uncharacterized ferredoxin-like protein yfhL | | Authors: | Giastas, P, Mavridis, M.I. | | Deposit date: | 2008-11-18 | | Release date: | 2009-08-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Insight into the protein and solvent contributions to the reduction potentials of [4Fe-4S]2+/+ clusters: crystal structures of the Allochromatium vinosum ferredoxin variants C57A and V13G and the homologous Escherichia coli ferredoxin
J.Biol.Inorg.Chem., 14, 2009
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1G8M
 | | CRYSTAL STRUCTURE OF AVIAN ATIC, A BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME IN PURINE BIOSYNTHESIS AT 1.75 ANG. RESOLUTION | | Descriptor: | AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION | | Authors: | Greasley, S.E, Horton, P, Beardsley, G.P, Benkovic, S.J, Wilson, I.A. | | Deposit date: | 2000-11-17 | | Release date: | 2001-04-27 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
Nat.Struct.Biol., 8, 2001
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3TNQ
 | | Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ... | | Authors: | Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S. | | Deposit date: | 2011-09-01 | | Release date: | 2012-02-01 | | Last modified: | 2012-09-26 | | Method: | X-RAY DIFFRACTION (3.097 Å) | | Cite: | Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
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2GOO
 | | Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Activin receptor type 2A, Bone morphogenetic protein 2, ... | | Authors: | Allendorph, G.P, Choe, S. | | Deposit date: | 2006-04-13 | | Release date: | 2006-05-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the ternary signaling complex of a TGF-beta superfamily member.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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5OIE
 | | Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) E419A variant in complex with serine and glycerol | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SERINE, ... | | Authors: | Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B. | | Deposit date: | 2017-07-18 | | Release date: | 2018-08-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.071 Å) | | Cite: | The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
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4NKW
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3KKI
 | | PLP-Dependent Acyl-CoA transferase CqsA | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CAI-1 autoinducer synthase, MAGNESIUM ION, ... | | Authors: | Kelly, R.C, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2009-11-05 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Nat.Chem.Biol., 5, 2009
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4NR6
 | | Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand | | Descriptor: | 1-[7-(3,4-dimethoxyphenyl)-9-{[(3R)-1-methylpiperidin-3-yl]methoxy}-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl]propan-1-one, CREB-binding protein | | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Hay, D, Fedorov, O, Martin, S, Chaikuad, A, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-11-26 | | Release date: | 2013-12-18 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Crystal structure of the bromodomain of human CREBBP in complex with an oxazepin ligand
To be Published
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4IZA
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1ZUJ
 | | The crystal structure of the Lactococcus lactis MG1363 DpsA protein | | Descriptor: | hypothetical protein Llacc01001955 | | Authors: | Stillman, T.J, Upadhyay, M, Norte, V.A, Sedelnikova, S.E, Carradus, M, Tzokov, S, Bullough, P.A, Shearman, C.A, Gasson, M.J, Williams, C.H, Artymiuk, P.J, Green, J. | | Deposit date: | 2005-05-31 | | Release date: | 2005-08-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structures of Lactococcus lactis MG1363 Dps proteins reveal the presence of an N-terminal helix that is required for DNA binding.
Mol.Microbiol., 57, 2005
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2AVW
 | | Crystal structure of monoclinic form of streptococcus Mac-1 | | Descriptor: | GLYCEROL, IgG-degrading protease, SULFATE ION | | Authors: | Agniswamy, J, Nagiec, M.J, Liu, M, Schuck, P, Musser, J.M, Sun, P.D. | | Deposit date: | 2005-08-30 | | Release date: | 2006-02-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of group a streptococcus mac-1: insight into dimer-mediated specificity for recognition of human IgG.
Structure, 14, 2006
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2PQ8
 | | MYST histone acetyltransferase 1 | | Descriptor: | COENZYME A, Probable histone acetyltransferase MYST1, UNKNOWN ATOM OR ION, ... | | Authors: | Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-01 | | Release date: | 2007-05-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | MYST histone acetyltransferase 1.
To be Published
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2JC5
 | | Apurinic Apyrimidinic (AP) endonuclease (NApe) from Neisseria Meningitidis | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, BICINE, EXODEOXYRIBONUCLEASE, ... | | Authors: | Carpenter, E.P, Corbett, A, Thomson, H, Adacha, J, Jensen, K, Bergeron, J, Kasampalidis, I, Exley, R, Winterbotham, M, Tang, C, Baldwin, G.S, Freemont, P. | | Deposit date: | 2006-12-19 | | Release date: | 2007-03-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
Embo J., 26, 2007
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2JFL
 | | CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE (DIPHOSPHORYLATED FORM) BOUND TO 5- AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | | Descriptor: | 1,2-ETHANEDIOL, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, CHLORIDE ION, ... | | Authors: | Pike, A.C.W, Rellos, P, Fedorov, O, Keates, T, Salah, E, Savitsky, P, Papagrigoriou, E, Bunkoczi, G, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | | Deposit date: | 2007-02-02 | | Release date: | 2007-02-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
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3KGC
 | | Isolated ligand binding domain dimer of GluA2 ionotropic glutamate receptor in complex with glutamate, LY 404187 and ZK 200775 | | Descriptor: | GLUTAMIC ACID, Glutamate receptor 2, N-[(2S)-2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide, ... | | Authors: | Sobolevsky, A.I, Rosconi, M.P, Gouaux, E. | | Deposit date: | 2009-10-28 | | Release date: | 2009-12-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
Nature, 462, 2009
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