2GYX

Crystal structure of DB884- D(CGCGAATTCGCG)2 complex at 1.86 A resolution.

Summary for 2GYX

• Entry DOI: 10.2210/pdb2gyx/pdb
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, N,N'-(1H-PYRROLE-2,5-DIYLDI-4,1-PHENYLENE)DIBENZENECARBOXIMIDAMIDE, ... (4 entities in total)
• Functional Keywords: b-type duplex dna, double helix, dodecamer, compound db 884., dna
• Total number of polymer chains: 2
• Total formula weight: 7806.64

Authors

Lee, M.P.H.,Neidle, S. (deposition date: 2006-05-10, release date: 2007-05-22, Last modification date: 2023-08-30)

• Primary citation: Munde, M.,Lee, M.P.H.,Neidle, S.,Arafa, R.,Boykin, D.W.,Liu, Y.,Bailly, C.,Wilson, W.D.; Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex.; J.Am.Chem.Soc., 129:5688-5698, 2007; PubMed: 17425312; DOI: 10.1021/ja069003n

Experimental method

X-RAY DIFFRACTION (1.86 Å)