4RVJ
| Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with amprenavir | Descriptor: | HIV-1 protease, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER | Authors: | Yedidi, R.S, Garimella, H, Kaufman, J.D, Das, D, Wingfield, P.T, Mitsuya, H. | Deposit date: | 2014-11-26 | Release date: | 2016-05-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1 To be Published
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1NAV
| Thyroid Receptor Alpha in complex with an agonist selective for Thyroid Receptor Beta1 | Descriptor: | SULFATE ION, hormone receptor alpha 1, THRA1, ... | Authors: | Ye, L, Li, Y.L, Mellstrom, K, Mellin, C, Bladh, L.G, Koehler, K, Garg, N, Garcia Collazo, A.M, Litten, C, Husman, B, Persson, K, Ljunggren, J, Grover, G, Sleph, P.G, George, R, Malm, J. | Deposit date: | 2002-11-29 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. J.Med.Chem., 46, 2003
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1NGW
| Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin | Descriptor: | Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ... | Authors: | Yin, J, Andryski, S.E, Beuscher IV, A.E, Stevens, R.C, Schultz, P.G. | Deposit date: | 2002-12-18 | Release date: | 2003-02-04 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural evidence for substrate strain in antibody catalysis Proc.Natl.Acad.Sci.USA, 100, 2003
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1NDD
| STRUCTURE OF NEDD8 | Descriptor: | CHLORIDE ION, PROTEIN (UBIQUITIN-LIKE PROTEIN NEDD8), SULFATE ION | Authors: | Whitby, F.G, Xia, G, Pickart, C.M, Hill, C.P. | Deposit date: | 1998-08-21 | Release date: | 1999-02-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes. J.Biol.Chem., 273, 1998
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1NIL
| A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN | Descriptor: | PAK PILIN, TRANS | Authors: | Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D. | Deposit date: | 1995-10-05 | Release date: | 1996-01-29 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design. Biochemistry, 34, 1995
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1NH1
| Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae. | Descriptor: | Avirulence B protein | Authors: | Lee, C.C, Wood, M.D, Ng, K, Luginbuhl, P, Spraggon, G, Katagiri, F. | Deposit date: | 2002-12-18 | Release date: | 2004-03-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae. Structure, 12, 2004
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4TXY
| Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog | Descriptor: | Cyclic AMP-GMP synthase, MAGNESIUM ION | Authors: | Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A. | Deposit date: | 2014-07-07 | Release date: | 2014-08-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.0001 Å) | Cite: | Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity. Cell, 158, 2014
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4TYS
| Crystal structure of Canavalia maritima lectin (ConM) complexed with a dinucleotide | Descriptor: | Concanavalin-A, bis{[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl]methyl} hydrogen phosphate | Authors: | Vieira, D.B.H.A, Delatorre, P, Silva-Filho, J.C, Nobrega, R.B, Cavada, B.S, Rocha, B.A.M, Lima, E.M, Teixeira, C.S. | Deposit date: | 2014-07-09 | Release date: | 2015-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structure of Canavalia maritima lectin (ConM) complexed with a dinucleotide To Be Published
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1NLB
| crystal structure of anti-HCV monoclonal antibody 19D9D6 | Descriptor: | antibody 19D9D6 heavy chain, antibody 19D9D6 light chain | Authors: | Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E. | Deposit date: | 2003-01-07 | Release date: | 2003-02-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a hydrophobic immunodominant
antigenic site on hepatitis C virus core protein
complexed to monoclonal antibody 19D9D6. J.Immunol., 170, 2003
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1N84
| HUMAN SERUM TRANSFERRIN, N-LOBE | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | Deposit date: | 2002-11-19 | Release date: | 2003-03-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY J.Biol.Chem., 278, 2003
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1N9S
| Crystal structure of yeast SmF in spacegroup P43212 | Descriptor: | Small nuclear ribonucleoprotein F | Authors: | Collins, B.M, Cubeddu, L, Naidoo, N, Harrop, S.J, Kornfeld, G.D, Dawes, I.W, Curmi, P.M.G, Mabbutt, B.C. | Deposit date: | 2002-11-26 | Release date: | 2002-12-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Homomeric ring assemblies of eukaryotic Sm proteins have affinity for
both RNA and DNA: Crystal structure of an oligomeric complex of yeast
SmF J.Biol.Chem., 278, 2003
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1NB8
| Structure of the catalytic domain of USP7 (HAUSP) | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y. | Deposit date: | 2002-12-02 | Release date: | 2003-01-07 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde Cell(Cambridge,Mass.), 111, 2002
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1NC9
| STREPTAVIDIN MUTANT Y43A WITH IMINOBIOTIN AT 1.8A RESOLUTION | Descriptor: | 2-IMINOBIOTIN, Streptavidin | Authors: | Le Trong, I, Freitag, S, Klumb, L.A, Chu, V, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 2002-12-05 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin. Acta Crystallogr.,Sect.D, 59, 2003
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1NE9
| Crystal Structure of Weissella viridescens FemX at 1.7 Ang Resolution | Descriptor: | FemX, MAGNESIUM ION | Authors: | Biarrotte-Sorin, S, Maillard, A.P, Delettre, J, Sougakoff, W, Arthur, M, Mayer, C. | Deposit date: | 2002-12-11 | Release date: | 2004-02-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of Weissella viridescens FemX and its complex with UDP-MurNAc-pentapeptide: insights into FemABX family substrates recognition. Structure, 12, 2004
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1NKX
| CRYSTAL STRUCTURE OF A PROTEOLYTICALLY GENERATED FUNCTIONAL MONOFERRIC C-LOBE OF BOVINE LACTOFERRIN AT 1.9A RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Sharma, S, Jasti, J, Kumar, J, Mohanty, A.K, Singh, T.P. | Deposit date: | 2003-01-06 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of a Proteolytically Generated Functional Monoferric C-lobe of
Bovine Lactoferrin at 1.9A Resolution J.Mol.Biol., 331, 2003
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1NK1
| NK1 FRAGMENT OF HUMAN HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR (HGF/SF) AT 2.5 ANGSTROM RESOLUTION | Descriptor: | PROTEIN (HEPATOCYTE GROWTH FACTOR PRECURSOR) | Authors: | Chirgadze, D.Y, Hepple, J.P, Zhou, H, Byrd, R.A, Blundell, T.L, Gherardi, E. | Deposit date: | 1998-08-20 | Release date: | 1999-01-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. Nat.Struct.Biol., 6, 1999
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1NL7
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4TUU
| Isolated p110a subunit of PI3Ka provides a platform for structure-based drug design | Descriptor: | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Chen, P, Deng, Y.-L, Bergqvist, S, Falk, M, Liu, W, Timofeevski, S. | Deposit date: | 2014-06-24 | Release date: | 2014-08-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Engineering of an isolated p110 alpha subunit of PI3K alpha permits crystallization and provides a platform for structure-based drug design. Protein Sci., 23, 2014
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4TVW
| Resorufin ligase with bound resorufin-AMP analog | Descriptor: | 5'-O-{[5-(7-hydroxy-3-oxo-3H-phenoxazin-2-yl)pentanoyl]sulfamoyl}adenosine, Lipoate-protein ligase A | Authors: | Goldman, P.J, Drennan, C.L. | Deposit date: | 2014-06-28 | Release date: | 2014-10-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.505 Å) | Cite: | Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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1NAL
| THE THREE-DIMENSIONAL STRUCTURE OF N-ACETYLNEURAMINATE LYASE FROM ESCHERICHIA COLI | Descriptor: | N-ACETYLNEURAMINATE LYASE, SULFATE ION | Authors: | Izard, T, Lawrence, M.C, Malby, R.L, Lilley, G.G, Colman, P.M. | Deposit date: | 1994-02-28 | Release date: | 1995-09-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The three-dimensional structure of N-acetylneuraminate lyase from Escherichia coli. Structure, 2, 1994
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1NDJ
| Streptavidin Mutant Y43F with Biotin at 1.81A Resolution | Descriptor: | BIOTIN, Streptavidin | Authors: | Le Trong, I, Freitag, S, Klumb, L.A, Chu, V, Stayton, P.S, Stenkamp, R.E. | Deposit date: | 2002-12-09 | Release date: | 2003-09-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural studies of hydrogen bonds in the high-affinity streptavidin-biotin complex: mutations of amino acids interacting with the ureido oxygen of biotin. Acta Crystallogr.,Sect.D, 59, 2003
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1NBF
| Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde | Descriptor: | Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y. | Deposit date: | 2002-12-02 | Release date: | 2003-01-07 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde Cell(Cambridge,Mass.), 111, 2002
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1NIM
| A COMPARISON OF NMR SOLUTION STRUCTURES OF THE RECEPTOR BINDING DOMAINS OF PSEUDOMONAS AERUGINOSA PILI STRAINS PAO, KB7, AND PAK: IMPLICATIONS FOR RECEPTOR BINDING AND SYNTHETIC VACCINE DESIGN | Descriptor: | PAK PILIN, TRANS | Authors: | Campbell, A.P, Mcinnes, C, Hodges, R.S, Sykes, B.D. | Deposit date: | 1995-10-05 | Release date: | 1996-01-29 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design. Biochemistry, 34, 1995
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1NGZ
| Chimeric Germline Fab 7g12-apo | Descriptor: | Germline Metal Chelatase Catalytic Antibody, Heavy chain, Light chain | Authors: | Yin, J, Andryski, S.A, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | Deposit date: | 2002-12-18 | Release date: | 2003-02-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural evidence for substrate strain in antibody catalysis Proc.Natl.Acad.Sci.USA, 100, 2003
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1NI0
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