6FJO
 
 | | Adenovirus species 26 knob protein, very high resolution | | 分子名称: | Fiber, GLUTAMIC ACID, GLYCEROL, ... | | 著者 | Rizkallah, P.J, Parker, A.L, Baker, A.T. | | 登録日 | 2018-01-22 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Sci Adv, 5, 2019
|
|
4QII
 | | Crystal Structure of type II MenB from Mycobacteria tuberculosis | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, Salicylyl CoA, TRIETHYLENE GLYCOL | | 著者 | Song, H.G, Tse, Y.S, Sung, H.P, Guo, Z.H. | | 登録日 | 2014-05-31 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6HGS
 | |
1D27
 | |
6MEH
 | |
5NOD
 | | PASTA subunit 4 of Streptococcus pneumoniae STKP crystallized with PEG and succinate | | 分子名称: | Serine/threonine-protein kinase StkP | | 著者 | Galisson, F, Gueguen-Chaignon, V, Gouet, P, Grangeasse, C, Zucchini, L. | | 登録日 | 2017-04-12 | | 公開日 | 2017-11-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | PASTA repeats of the protein kinase StkP interconnect cell constriction and separation of Streptococcus pneumoniae.
Nat Microbiol, 3, 2018
|
|
8U3H
 | |
8U3F
 | |
6W5H
 | | 1.85 A resolution structure of Norovirus 3CL protease in complex with inhibitor 5d | | 分子名称: | 2-(3-chlorophenyl)-2-methylpropyl [(2S)-3-cyclohexyl-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]carbamate, 3C-LIKE PROTEASE | | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rathnayake, A.D, Kim, Y, Chang, K.O, Groutas, W.C. | | 登録日 | 2020-03-13 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.
J.Med.Chem., 63, 2020
|
|
1D6S
 | | CRYSTAL STRUCTURE OF THE K41A MUTANT OF O-ACETYLSERINE SULFHYDRYLASE COMPLEXED IN EXTERNAL ALDIMINE LINKAGE WITH METHIONINE | | 分子名称: | METHIONINE, O-ACETYLSERINE SULFHYDRYLASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Burkhard, P, Tai, C.H, Ristroph, C.M, Cook, P.F, Jansonius, J.N. | | 登録日 | 1999-10-15 | | 公開日 | 2000-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium.
J.Mol.Biol., 291, 1999
|
|
6HWM
 | | Structure of Thermus thermophilus ClpP in complex with bortezomib | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, DI(HYDROXYETHYL)ETHER, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | | 著者 | Felix, J, Schanda, P, Fraga, H, Morlot, C. | | 登録日 | 2018-10-12 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.
Sci Adv, 5, 2019
|
|
3OS8
 | | Estrogen Receptor | | 分子名称: | 4-[1-benzyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol, Estrogen receptor | | 著者 | Bruning, J, Parent, A.A, Gil, G, Zhao, M, Nowak, J, Pace, M.C, Smith, C.L, Afonine, P.V, Adams, P.D, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2010-09-08 | | 公開日 | 2010-11-10 | | 最終更新日 | 2021-10-06 | | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | | 主引用文献 | Coupling of receptor conformation and ligand orientation determine graded activity.
Nat.Chem.Biol., 6, 2010
|
|
6M65
 | | Crystal structure of Mycobacterium smegmatis MutT1 in complex with GMPPNP (GDP) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Raj, P, Karthik, S, Arif, S.M, Varshney, U, Vijayan, M. | | 登録日 | 2020-03-13 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1.
Acta Crystallogr D Struct Biol, 76, 2020
|
|
1TFD
 | |
6W8T
 | | Crystal structure of metacaspase 4 from Arabidopsis (microcrystals treated with calcium) | | 分子名称: | Metacaspase-4, SULFATE ION | | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | | 登録日 | 2020-03-21 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase.
Nat Commun, 11, 2020
|
|
1D9H
 | | Structural origins of the exonuclease resistance of a zwitterionic RNA | | 分子名称: | DNA/RNA (5'-D(*GP*CP*GP*TP*AP)-R(*(U31)P)-D(*AP*CP*GP*C)-3') | | 著者 | Teplova, M, Wallace, S.T, Tereshko, V, Minasov, G, Simons, A.M, Cook, P.D, Manoharan, M, Egli, M. | | 登録日 | 1999-10-27 | | 公開日 | 1999-12-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural origins of the exonuclease resistance of a zwitterionic RNA
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
4MDO
 | | Crystal structure of a GH1 beta-glucosidase from the fungus Humicola insolens | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Giuseppe, P.O, Souza, T.A.C.B, Souza, F.H.M, Zanphorlin, L.M, Machado, C.B, Ward, R.J, Jorge, J.A, Furriel, R.P.M, Murakami, M.T. | | 登録日 | 2013-08-23 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for glucose tolerance in GH1 beta-glucosidases.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
4QNN
 | |
4CPG
 | |
8DGJ
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
|
|
3K8D
 | | Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-manno-octulosonate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Heyes, D.J, Levy, C.W, Lafite, P, Scrutton, N.S, Leys, D. | | 登録日 | 2009-10-14 | | 公開日 | 2009-11-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
J.Biol.Chem., 284, 2009
|
|
8DGI
 | | Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia | | 分子名称: | Endoribonuclease Dcr-1, Loquacious, isoform B | | 著者 | Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. | | 登録日 | 2022-06-23 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB.
Mol.Cell, 82, 2022
|
|
6VLE
 | | Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 in its Apo-form | | 分子名称: | Alpha-(1,6)-fucosyltransferase, SULFATE ION | | 著者 | Jarva, M.A, Dramicanin, M, Lingford, J.P, Mao, R, John, A, Goddard-Borger, E.D. | | 登録日 | 2020-01-23 | | 公開日 | 2020-02-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural basis of substrate recognition and catalysis by fucosyltransferase 8.
J.Biol.Chem., 295, 2020
|
|
8D64
 | | ELIC with cysteamine in POPC nanodisc | | 分子名称: | 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel | | 著者 | Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L. | | 登録日 | 2022-06-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
|
|
3DV2
 | | Crystal Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis | | 分子名称: | Nicotinate (Nicotinamide) nucleotide adenylyltransferase, SULFATE ION | | 著者 | Lu, S, Smith, C.D, Yang, Z, Pruett, P.S, Nagy, L, McCombs, D.P, DeLucas, L.J, Brouillette, W.J, Brouillette, C.G. | | 登録日 | 2008-07-18 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
|
|
