4MPK
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![BU of 4mpk by Molmil](/molmil-images/mine/4mpk) | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, GLYCEROL | 著者 | Yamini, S, Chaudhary, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-09-13 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of the complex of buffalo signaling protein SPB-40 with N-acetylglucosamine at 2.65 A resolution To be Published
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4E7J
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![BU of 4e7j by Molmil](/molmil-images/mine/4e7j) | PFV integrase Target Capture Complex, Apo form (TCC-Apo), at 3.15 A resolution | 分子名称: | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... | 著者 | Maertens, G.N, Cherepanov, P. | 登録日 | 2012-03-17 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.1501 Å) | 主引用文献 | 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo. Embo J., 468, 2012
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6FCI
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![BU of 6fci by Molmil](/molmil-images/mine/6fci) | Crystal Structure of Human APRT wild type in complex with Adenine, PRPP and Mg2+ | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENINE, Adenine phosphoribosyltransferase, ... | 著者 | Nioche, P, Huyet, J, Ozeir, M. | 登録日 | 2017-12-20 | 公開日 | 2018-08-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase. Cell Chem Biol, 25, 2018
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7THT
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![BU of 7tht by Molmil](/molmil-images/mine/7tht) | CryoEM structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1042 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 heavy chain, ... | 著者 | Manne, K, May, A, Acharya, P. | 登録日 | 2022-01-12 | 公開日 | 2022-02-16 | 最終更新日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022
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6OXJ
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![BU of 6oxj by Molmil](/molmil-images/mine/6oxj) | |
5SXS
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![BU of 5sxs by Molmil](/molmil-images/mine/5sxs) | |
7BVB
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![BU of 7bvb by Molmil](/molmil-images/mine/7bvb) | |
5AGU
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![BU of 5agu by Molmil](/molmil-images/mine/5agu) | The sliding clamp of Mycobacterium tuberculosis in complex with a natural product. | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ... | 著者 | Lukat, P, Kling, A, Heinz, D.W, Mueller, R. | 登録日 | 2015-02-03 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.173 Å) | 主引用文献 | Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
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3E6L
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![BU of 3e6l by Molmil](/molmil-images/mine/3e6l) | Structure of murine INOS oxygenase domain with inhibitor AR-C132283 | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, Nitric oxide synthase, ... | 著者 | Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D. | 登録日 | 2008-08-15 | 公開日 | 2008-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat.Chem.Biol., 4, 2008
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8OIV
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![BU of 8oiv by Molmil](/molmil-images/mine/8oiv) | Monkeypox virus VP39 in complex with SAH and cap0 | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Skvara, P, Chalupska, D, Silhan, J, Klima, M, Boura, E. | 登録日 | 2023-03-23 | 公開日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39. Antiviral Res., 216, 2023
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7K4X
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![BU of 7k4x by Molmil](/molmil-images/mine/7k4x) | Crystal structure of Kemp Eliminase HG3.7 in complex with the transition state analog 6-nitrobenzotriazole | 分子名称: | 6-NITROBENZOTRIAZOLE, ACETATE ION, Endo-1,4-beta-xylanase, ... | 著者 | Padua, R.A.P, Otten, R, Bunzel, A, Nguyen, V, Pitsawong, W, Patterson, M, Sui, S, Perry, S.L, Cohen, A.E, Hilvert, D, Kern, D. | 登録日 | 2020-09-16 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | How directed evolution reshapes the energy landscape in an enzyme to boost catalysis. Science, 370, 2020
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6SU6
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![BU of 6su6 by Molmil](/molmil-images/mine/6su6) | Complex between a UDP-glucosyltransferase from Polygonum tinctorium capable of glucosylating indoxyl and UDP-glucose | 分子名称: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Fredslund, F, Teze, D, Svensson, B, Adams, P.D, Welner, D.H. | 登録日 | 2019-09-13 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | O-/N-/S-Specificity in Glycosyltransferase Catalysis: From Mechanistic Understanding to Engineering Acs Catalysis, 11, 2021
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5AE8
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![BU of 5ae8 by Molmil](/molmil-images/mine/5ae8) | Crystal structure of mouse PI3 kinase delta in complex with GSK2269557 | 分子名称: | 6-(1H-Indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Down, K.D, Amour, A, Baldwin, I.R, Cooper, A.W.J, Deakin, A.M, Felton, L.M, Guntrip, S.B, Hardy, C, Harrison, Z.A, Jones, K.L, Jones, P, Keeling, S.E, Le, J, Livia, S, Lucas, F, Lunniss, C.J, Parr, N.J, Robinson, E, Rowland, P, Smith, S, Thomas, D.A, Vitulli, G, Washio, Y, Hamblin, N. | 登録日 | 2015-08-26 | 公開日 | 2015-09-16 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase Gamma for the Treatment of Respiratory Disease. J.Med.Chem., 58, 2015
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5AE9
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![BU of 5ae9 by Molmil](/molmil-images/mine/5ae9) | Crystal structure of mouse PI3 kinase delta in complex with GSK2292767 | 分子名称: | N-[5-[4-(5-{[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]METHYL}-1,3-OXAZOL-2-YL)-1H-INDAZOL-6-YL]-2-(METHYLOXY)-3-PYRIDINYL]METHANESULFONAMIDE, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Down, K.D, Amour, A, Baldwin, I.R, Cooper, A.W.J, Deakin, A.M, Felton, L.M, Guntrip, S.B, Hardy, C, Harrison, Z.A, Jones, K.L, Jones, P, Keeling, S.E, Le, J, Livia, S, Lucas, F, Lunniss, C.J, Parr, N.J, Robinson, E, Rowland, P, Smith, S, Thomas, D.A, Vitulli, G, Washio, Y, Hamblin, N. | 登録日 | 2015-08-26 | 公開日 | 2015-09-16 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase Gamma for the Treatment of Respiratory Disease. J.Med.Chem., 58, 2015
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2X53
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![BU of 2x53 by Molmil](/molmil-images/mine/2x53) | Structure of the phage p2 baseplate in its activated conformation with Sr | 分子名称: | ORF15, ORF16, PUTATIVE RECEPTOR BINDING PROTEIN, ... | 著者 | Sciara, G, Bebeacua, C, Bron, P, Tremblay, D, Ortiz-Lombardia, M, Lichiere, J, van Heel, M, Campanacci, V, Moineau, S, Cambillau, C. | 登録日 | 2010-02-05 | 公開日 | 2010-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of Lactococcal Phage P2 Baseplate and its Mechanism of Activation. Proc.Natl.Acad.Sci.USA, 107, 2010
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6OD2
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![BU of 6od2 by Molmil](/molmil-images/mine/6od2) | Yeast Spc42 C-terminal Antiparallel Coiled-Coil | 分子名称: | Spindle pole body component SPC42 | 著者 | Drennan, A.C, Krishna, S, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jaspersen, S.L, Rayment, I. | 登録日 | 2019-03-25 | 公開日 | 2019-04-24 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.435 Å) | 主引用文献 | Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Mol.Biol.Cell, 30, 2019
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7TOK
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![BU of 7tok by Molmil](/molmil-images/mine/7tok) | Crystal structure of the CBM domain of carbohydrate esterase FjoAcXE | 分子名称: | Acetylxylan esterase I | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | 登録日 | 2022-01-24 | 公開日 | 2022-04-13 | 最終更新日 | 2022-11-02 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans. Molecules, 27, 2022
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6FII
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![BU of 6fii by Molmil](/molmil-images/mine/6fii) | Tubulin-Spongistatin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Menchon, G, Prota, A.E, Lucena Angell, D, Bucher, P, Mueller, R, Paterson, I, Diaz, J.F, Altmann, K.-H, Steinmetz, M.O. | 登録日 | 2018-01-18 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. Nat Commun, 9, 2018
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6UZV
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![BU of 6uzv by Molmil](/molmil-images/mine/6uzv) | The structure of a red shifted photosystem I complex | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Toporik, H, Williams, D, Chiu, P.L, Mazor, Y. | 登録日 | 2019-11-15 | 公開日 | 2020-09-16 | 最終更新日 | 2020-11-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The structure of a red-shifted photosystem I reveals a red site in the core antenna. Nat Commun, 11, 2020
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1S03
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5TY8
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![BU of 5ty8 by Molmil](/molmil-images/mine/5ty8) | Identification of a New Zinc Binding Chemotype by Fragment Screening | 分子名称: | (5R)-5-phenyl-1,3-oxazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION | 著者 | Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. | 登録日 | 2016-11-18 | 公開日 | 2017-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
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6BCU
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4C6T
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![BU of 4c6t by Molmil](/molmil-images/mine/4c6t) | Crystal structure of the RPS4 and RRS1 TIR domain heterodimer | 分子名称: | DISEASE RESISTANCE PROTEIN RPS4, MALONIC ACID, PROBABLE WRKY TRANSCRIPTION FACTOR 52 | 著者 | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | 登録日 | 2013-09-19 | 公開日 | 2014-05-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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7BZC
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![BU of 7bzc by Molmil](/molmil-images/mine/7bzc) | Crystal structure of plant sesterterpene synthase AtTPS18 complexed with farnesyl thiolodiphosphate (FSPP) | 分子名称: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Terpenoid synthase 18 | 著者 | Li, J.X, Wang, G.D, Zhang, P. | 登録日 | 2020-04-27 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases. Plant Commun., 1, 2020
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7TOJ
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![BU of 7toj by Molmil](/molmil-images/mine/7toj) | Crystal structure of carbohydrate esterase CspAcXE, apoenzyme | 分子名称: | CHLORIDE ION, SGNH/GDSL hydrolase family protein | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. | 登録日 | 2022-01-24 | 公開日 | 2022-04-13 | 最終更新日 | 2022-11-02 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans. Molecules, 27, 2022
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