4NYG
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![BU of 4nyg by Molmil](/molmil-images/mine/4nyg) | Crystal structure of the E. coli thiM riboswitch in complex with thiamine | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, MAGNESIUM ION, thiM TPP riboswitch | 著者 | Warner, K.D, Homan, P, Weeks, K.M, Smith, A.G, Abell, C, Ferre-D'Amare, A.R. | 登録日 | 2013-12-10 | 公開日 | 2014-06-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Validating Fragment-Based Drug Discovery for Biological RNAs: Lead Fragments Bind and Remodel the TPP Riboswitch Specifically. Chem.Biol., 21, 2014
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1GHB
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![BU of 1ghb by Molmil](/molmil-images/mine/1ghb) | A SECOND ACTIVE SITE IN CHYMOTRYPSIN? THE X-RAY CRYSTAL STRUCTURE OF N-ACETYL-D-TRYPTOPHAN BOUND TO GAMMA-CHYMOTRYPSIN | 分子名称: | ACETYL GROUP, GAMMA-CHYMOTRYPSIN, HEXANE, ... | 著者 | Yennawar, H.P, Yennawar, N.H, Farber, G.K. | 登録日 | 1994-04-06 | 公開日 | 1994-06-22 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A STRUCTURAL EXPLANATION FOR ENZYME MEMORY IN NONAQUEOUS SOLVENTS. J.Am.Chem.Soc., 117, 1995
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4UYN
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![BU of 4uyn by Molmil](/molmil-images/mine/4uyn) | SAR156497 an exquisitely selective inhibitor of Aurora kinases | 分子名称: | AURORA KINASE A, ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | 著者 | Carry, J.C, Clerc, F, Minoux, H, Schio, L, Mauger, J, Nair, A, Parmantier, E, Lemoigne, R, Delorme, C, Nicolas, J.P, Krick, A, Abecassis, P.Y, Crocq-Stuerga, V, Pouzieux, S, Delarbre, L, Maignan, S, Bertrand, T, Bjergarde, K, Ma, N, Lachaud, S, Guizani, H, Lebel, R, Doerflinger, G, Monget, S, Perron, S, Gasse, F, Angouillant-Boniface, O, Filoche-Romme, B, Murer, M, Gontier, S, Prevost, C, Monteiro, M.L, Combeau, C. | 登録日 | 2014-09-02 | 公開日 | 2014-11-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sar156497, an Exquisitely Selective Inhibitor of Aurora Kinases. J.Med.Chem., 58, 2015
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6TRF
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![BU of 6trf by Molmil](/molmil-images/mine/6trf) | Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) purified from cells treated with kifunensine. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Zitzmann, N. | 登録日 | 2019-12-18 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.106 Å) | 主引用文献 | Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase. Structure, 29, 2021
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4W1P
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![BU of 4w1p by Molmil](/molmil-images/mine/4w1p) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 5.54 MGy TEMP 150K | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | 登録日 | 2014-08-14 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4W1Q
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![BU of 4w1q by Molmil](/molmil-images/mine/4w1q) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 7.39 MGy TEMP 150K | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | 登録日 | 2014-08-14 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4W1S
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![BU of 4w1s by Molmil](/molmil-images/mine/4w1s) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 11.09 MGy TEMP 150K | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | jackson, C.j, carr, p.d, weik, m, huber, t, meirelles, t, correy, g. | 登録日 | 2014-08-14 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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2Q5Z
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![BU of 2q5z by Molmil](/molmil-images/mine/2q5z) | Crystal structure of iMazG from Vibrio DAT 722: Ntag-iMazG (P43212) | 分子名称: | GLYCEROL, Hypothetical protein, MAGNESIUM ION | 著者 | Robinson, A, Guilfoyle, A.P, Harrop, S.J, Boucher, Y, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C. | 登録日 | 2007-06-04 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype. Mol.Microbiol., 66, 2007
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5HYU
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6TSV
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![BU of 6tsv by Molmil](/molmil-images/mine/6tsv) | Tail of empty GTA particle computed with helical refinement, C6 symmetry | 分子名称: | Tail tube protein Rcc01691 | 著者 | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | 登録日 | 2019-12-21 | 公開日 | 2020-07-22 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
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6TSW
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![BU of 6tsw by Molmil](/molmil-images/mine/6tsw) | Isometric capsid of empty GTA particle computed with I4(I,n25r) symmetry | 分子名称: | Major capsid protein Rcc01687 | 著者 | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | 登録日 | 2019-12-21 | 公開日 | 2020-07-22 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structure and mechanism of DNA delivery of a gene transfer agent. Nat Commun, 11, 2020
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5HVH
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![BU of 5hvh by Molmil](/molmil-images/mine/5hvh) | Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with two Inhibitory Nanobodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ... | 著者 | Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2016-01-28 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. J.Thromb.Haemost., 14, 2016
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5HSA
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![BU of 5hsa by Molmil](/molmil-images/mine/5hsa) | Alcohol Oxidase AOX1 from Pichia Pastoris | 分子名称: | ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, Alcohol oxidase 1, CALCIUM ION, ... | 著者 | Neumann, P, Ficner, R, Feussner, I, Koch, C. | 登録日 | 2016-01-25 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal Structure of Alcohol Oxidase from Pichia pastoris. Plos One, 11, 2016
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4NPP
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![BU of 4npp by Molmil](/molmil-images/mine/4npp) | The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms | 分子名称: | NICKEL (II) ION, Proton-gated ion channel | 著者 | Sauguet, L, Shahsavar, A, Poitevin, F, Huon, C, Menny, A, Nemecz, A, Haouz, A, Changeux, J.P, Corringer, P.J, Delarue, M. | 登録日 | 2013-11-22 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc.Natl.Acad.Sci.USA, 111, 2014
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5HVG
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![BU of 5hvg by Molmil](/molmil-images/mine/5hvg) | Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-a204) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2016-01-28 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. J.Thromb.Haemost., 14, 2016
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3G1E
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![BU of 3g1e by Molmil](/molmil-images/mine/3g1e) | X-ray crystal structure of coil 1A of human vimentin | 分子名称: | Vimentin | 著者 | Meier, M, Padilla, G.P, Herrmann, H, Wedig, T, Hergt, M, Patel, T.R, Stetefeld, J, Aebi, U, Burkhard, P. | 登録日 | 2009-01-29 | 公開日 | 2009-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J.Mol.Biol., 390, 2009
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4NR4
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![BU of 4nr4 by Molmil](/molmil-images/mine/4nr4) | Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand | 分子名称: | 1,2-ETHANEDIOL, 1-(4-chlorobenzyl)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1H-benzimidazole, CREB-binding protein, ... | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Hay, D, Fedorov, O, Martin, S, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-11-26 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Crystal structure of the bromodomain of human CREBBP in complex with an isoxazolyl-benzimidazole ligand TO BE PUBLISHED
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2Q73
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![BU of 2q73 by Molmil](/molmil-images/mine/2q73) | Crystal structure of iMazG from Vibrio DAT 722: Ctag-iMazG (P41212) | 分子名称: | Hypothetical protein, MAGNESIUM ION | 著者 | Robinson, A, Guilfoyle, A.P, Harrop, S.J, Boucher, Y, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C. | 登録日 | 2007-06-05 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype. Mol.Microbiol., 66, 2007
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5I2I
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2Q8Z
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![BU of 2q8z by Molmil](/molmil-images/mine/2q8z) | Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. | 登録日 | 2007-06-12 | 公開日 | 2008-01-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase. J.Med.Chem., 51, 2008
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3GH8
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![BU of 3gh8 by Molmil](/molmil-images/mine/3gh8) | Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and di-iodotyrosine (DIT) | 分子名称: | 3,5-DIIODOTYROSINE, FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1, ... | 著者 | Thomas, S.R, McTamney, P.M, Adler, J.M, LaRonde-LeBlanc, N, Rokita, S.E. | 登録日 | 2009-03-03 | 公開日 | 2009-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands. J.Biol.Chem., 284, 2009
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4NWN
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![BU of 4nwn by Molmil](/molmil-images/mine/4nwn) | Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T32-28 | 分子名称: | Propanediol utilization: polyhedral bodies pduT, Uncharacterized protein | 著者 | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | 登録日 | 2013-12-06 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
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3FV3
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![BU of 3fv3 by Molmil](/molmil-images/mine/3fv3) | Secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A | 分子名称: | GLYCEROL, SULFATE ION, Sapp1p-secreted aspartic protease 1, ... | 著者 | Dostal, J, Brynda, J, Hruskova-Heidingsfeldova, O, Sieglova, I, Pichova, I, Rezacova, P. | 登録日 | 2009-01-15 | 公開日 | 2009-05-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A J.Struct.Biol., 167, 2009
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4W92
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![BU of 4w92 by Molmil](/molmil-images/mine/4w92) | Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, C-di-AMP ribsoswitch, ... | 著者 | Jones, C.P, Ferre-D'Amare, A.R. | 登録日 | 2014-08-26 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.209 Å) | 主引用文献 | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
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6U2H
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![BU of 6u2h by Molmil](/molmil-images/mine/6u2h) | BRAF dimer bound to 14-3-3 | 分子名称: | 14-3-3 protein zeta/delta, 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, Serine/threonine-protein kinase B-raf | 著者 | Liau, N.P.D, Hymowitz, S.G, Sudhamsu, J. | 登録日 | 2019-08-19 | 公開日 | 2019-08-28 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization. Nat.Struct.Mol.Biol., 27, 2020
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