1TZY
 
 | | Crystal Structure of the Core-Histone Octamer to 1.90 Angstrom Resolution | | 分子名称: | CHLORIDE ION, HISTONE H3, HISTONE H4-VI, ... | | 著者 | Wood, C.M, Nicholson, J.M, Chantalat, L, Reynolds, C.D, Lambert, S.J, Baldwin, J.P. | | 登録日 | 2004-07-12 | | 公開日 | 2004-08-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High-resolution structure of the native histone octamer.
Acta Crystallogr.,Sect.F, 61, 2005
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6AV9
 | | CryoEM structure of Mical Oxidized Actin (Class 1) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | | 著者 | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | | 登録日 | 2017-09-01 | | 公開日 | 2018-01-17 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Catastrophic disassembly of actin filaments via Mical-mediated oxidation.
Nat Commun, 8, 2017
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6F1Y
 | | Dynein light intermediate chain region of the dynein tail/dynactin/BICDR1 complex | | 分子名称: | Cytoplasmic dynein 1 heavy chain 1,Dynein heavy chain, Cytoplasmic dynein 1 light intermediate chain 2 | | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | 登録日 | 2017-11-23 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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1E0B
 | | Chromo shadow domain from fission yeast swi6 protein. | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, SWI6 PROTEIN | | 著者 | Cowieson, N.P, Partridge, J.F, Allshire, R.C, Mclaughlin, P.J. | | 登録日 | 2000-03-16 | | 公開日 | 2000-05-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Dimerisation of Chromo Shadow Domain and Distinctions from the Chromodomain as Revealed by Structural Analysis
Curr.Biol., 10, 2000
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6GU3
 | | CDK1/CyclinB/Cks2 in complex with AZD5438 | | 分子名称: | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine, Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, ... | | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | | 登録日 | 2018-06-19 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
Cell Chem Biol, 26, 2019
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5Y72
 | | DMSPP Bound AmbP3 | | 分子名称: | AmbP3, DIMETHYLALLYL S-THIOLODIPHOSPHATE | | 著者 | Wong, C.P, Awakawa, T, Nakashima, Y. | | 登録日 | 2017-08-16 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3
Angew. Chem. Int. Ed. Engl., 57, 2018
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1GY8
 | | Trypanosoma brucei UDP-galactose 4' epimerase | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE 4-EPIMERASE, URIDINE-5'-DIPHOSPHATE | | 著者 | Shaw, M.P, Bond, C.S, Hunter, W.N. | | 登録日 | 2002-04-21 | | 公開日 | 2003-05-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-Resolution Crystal Structure of Trypanosoma Brucei Udp-Galactose 4'-Epimerase: A Potential Target for Structure-Based Development of Novel Trypanocides
Mol.Biochem.Parasitol., 126, 2003
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5EWI
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6AXO
 | | F96S Epi-isozizaene synthase | | 分子名称: | Epi-isozizaene synthase | | 著者 | Blank, P.N, Barrow, G.H, Christianson, D.W. | | 登録日 | 2017-09-07 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017
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6GWN
 | | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | | 分子名称: | Plasminogen activator inhibitor 1, VHH-2g-42, VHH-2w-64 | | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | | 登録日 | 2018-06-25 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
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5EXX
 | | AAA+ ATPase FleQ from Pseudomonas aeruginosa bound to c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION, Transcriptional regulator FleQ | | 著者 | Navarro, M.V.A.S, Sondermann, H, Krasteva, P.V. | | 登録日 | 2015-11-24 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.311 Å) | | 主引用文献 | Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2IXB
 | | Crystal structure of N-ACETYLGALACTOSAMINIDASE in complex with GalNAC | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ... | | 著者 | Sulzenbacher, G, Liu, Q.P, Bourne, Y, Henrissat, B, Clausen, H. | | 登録日 | 2006-07-07 | | 公開日 | 2007-04-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Bacterial Glycosidases for the Production of Universal Red Blood Cells.
Nat.Biotechnol., 25, 2007
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6F4E
 | | Crystal structure of the zinc-free catalytic domain of botulinum neurotoxin X | | 分子名称: | Catalytic domain of botulinum neurotoxin X, DI(HYDROXYETHYL)ETHER | | 著者 | Masuyer, G, Henriksson, L, Kosenina, S, Zhang, S, Barkho, S, Shen, Y, Dong, M, Stenmark, P. | | 登録日 | 2017-11-29 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity.
Sci Rep, 8, 2018
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1E0Q
 | | Mutant Peptide from the first N-terminal 17 amino-acid of Ubiquitin | | 分子名称: | POLYUBIQUITIN-B | | 著者 | Zerella, R, Chen, P.Y, Evans, P.A, Raine, A, Williams, D.H. | | 登録日 | 2000-04-05 | | 公開日 | 2001-01-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Characterization of a Mutant Peptide Derived from Ubiquitin: Implications for Protein Folding.
Protein Sci., 9, 2000
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3F70
 | | Crystal structure of L3MBTL2-H4K20me1 complex | | 分子名称: | Lethal(3)malignant brain tumor-like 2 protein, N-METHYL-LYSINE | | 著者 | Guo, Y, Qi, C, Allali-Hassani, A, Pan, P, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Botchkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-07 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Nucleic Acids Res., 37, 2009
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1H62
 | | Structure of Pentaerythritol tetranitrate reductase in complex with 1,4-androstadien-3,17-dione | | 分子名称: | ANDROSTA-1,4-DIENE-3,17-DIONE, FLAVIN MONONUCLEOTIDE, PENTAERYTHRITOL TETRANITRATE REDUCTASE | | 著者 | Barna, T.M, Moody, P.C.E. | | 登録日 | 2001-06-04 | | 公開日 | 2001-07-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Pentaerythritol Tetranitrate Reductase: "Flipped" Binding Geometries for Steroid Substrates in Different Redox States of the Enzyme
J.Mol.Biol., 310, 2001
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6AYN
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6EZT
 | | Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase D437A inactive mutant from Vibrio harveyi | | 分子名称: | Beta-N-acetylglucosaminidase Nag2, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | | 著者 | Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W. | | 登録日 | 2017-11-16 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi
To Be Published
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6H4E
 | | Proteus mirabilis N-acetylneuraminate lyase | | 分子名称: | Putative N-acetylneuraminate lyase, SULFATE ION | | 著者 | North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R. | | 登録日 | 2018-07-21 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.561 Å) | | 主引用文献 | The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond
To Be Published
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5EZN
 | | Crystal Structure of PfCyRPA | | 分子名称: | Cysteine-rich protective antigen | | 著者 | Favuzza, P, Pluschke, G, Rudolph, M.G. | | 登録日 | 2015-11-26 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife, 6, 2017
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5YCW
 | | Double domain swapped dimer of engineered hairpin loop1 and loop3 mutant in Single-chain Monellin | | 分子名称: | single chain monellin | | 著者 | Surana, P, Nandwani, N, Udgaonkar, J.B, Gosavi, S, Das, R. | | 登録日 | 2017-09-08 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.285 Å) | | 主引用文献 | A five-residue motif for the design of domain swapping in proteins.
Nat Commun, 10, 2019
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6AZK
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6B1N
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6ETU
 | | Crystal structure of KDM4D with tetrazolhydrazide compound 7 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... | | 著者 | Malecki, P.H, Link, A, Weiss, M.S, Heinemann, U. | | 登録日 | 2017-10-27 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases.
Chemmedchem, 14, 2019
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2V2W
 | | T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT | | 分子名称: | BETA-2 MICROGLOBULIN, HIV P17, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Lee, J.K, Stewart-Jones, G, Dong, T, Harlos, K, Di Gleria, K, Dorrell, L, Douek, D.C, Van Der Merwe, P.A, Jones, E.Y, Mcmichael, A.J. | | 登録日 | 2007-06-07 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
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