3F70

Crystal structure of L3MBTL2-H4K20me1 complex

Replaces:  3DBB

Summary for 3F70

Related3CEY
DescriptorLethal(3)malignant brain tumor-like 2 protein, N-METHYL-LYSINE (3 entities in total)
Functional Keywordsmbt, chromatin regulator, metal-binding, nucleus, transcription, transcription regulation, zinc-finger, transcription regulator, structural genomics, structural genomics consortium, sgc, phosphoprotein
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q969R5
Total number of polymer chains2
Total molecular weight104614.45
Authors
Primary citation
Guo, Y.,Nady, N.,Qi, C.,Allali-Hassani, A.,Zhu, H.,Pan, P.,Adams-Cioaba, M.A.,Amaya, M.F.,Dong, A.,Vedadi, M.,Schapira, M.,Read, R.J.,Arrowsmith, C.H.,Min, J.
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Nucleic Acids Res., 37:2204-2210, 2009
PubMed: 19233876 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkp086
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26610 0.9% 7.4% 6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171313
PDB entries from 2020-11-18