7XW6
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![BU of 7xw6 by Molmil](/molmil-images/mine/7xw6) | TSHR-Gs-M22 antibody-ML109 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Duan, J, Xu, P, Luan, X, Ji, Y, Yuan, Q, He, X, Ye, J, Cheng, X, Jiang, H, Zhang, S, Jiang, Y, Xu, H.E. | 登録日 | 2022-05-26 | 公開日 | 2022-08-17 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Hormone- and antibody-mediated activation of the thyrotropin receptor. Nature, 609, 2022
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2JEP
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![BU of 2jep by Molmil](/molmil-images/mine/2jep) | Native family 5 xyloglucanase from Paenibacillus pabuli | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, XYLOGLUCANASE | 著者 | Gloster, T.M, Ibatullin, F.M, Macauley, K, Eklof, J.M, Roberts, S, Turkenburg, J.P, Bjornvad, M.E, Jorgensen, P.L, Danielsen, S, Johansen, K, Borchert, T.V, Wilson, K.S, Brumer, H, Davies, G.J. | 登録日 | 2007-01-18 | 公開日 | 2007-03-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Characterization and Three-Dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families Gh5 and Gh12. J.Biol.Chem., 282, 2007
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3GSW
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![BU of 3gsw by Molmil](/molmil-images/mine/3gsw) | Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8A peptide variant | 分子名称: | Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8A (NLVPMVAAV), ... | 著者 | Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. | 登録日 | 2009-03-27 | 公開日 | 2009-08-04 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
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1V3B
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![BU of 1v3b by Molmil](/molmil-images/mine/1v3b) | Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Lawrence, M.C, Borg, N.A, Streltsov, V.A, Pilling, P.A, Epa, V.C, Varghese, J.N, McKimm-Breschkin, J.L, Colman, P.M. | 登録日 | 2003-10-30 | 公開日 | 2004-02-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III J.Mol.Biol., 335, 2004
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1L0B
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![BU of 1l0b by Molmil](/molmil-images/mine/1l0b) | Crystal Structure of rat Brca1 tandem-BRCT region | 分子名称: | BRCA1 | 著者 | Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P. | 登録日 | 2002-02-08 | 公開日 | 2002-03-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev., 16, 2002
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2JG9
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![BU of 2jg9 by Molmil](/molmil-images/mine/2jg9) | Crystallographic structure of human C1q globular heads (P1) | 分子名称: | CALCIUM ION, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ... | 著者 | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | 登録日 | 2007-02-09 | 公開日 | 2008-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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3GZ3
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![BU of 3gz3 by Molmil](/molmil-images/mine/3gz3) | |
3RCW
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![BU of 3rcw by Molmil](/molmil-images/mine/3rcw) | Crystal Structure of the bromodomain of human BRD1 | 分子名称: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ACETATE ION, ... | 著者 | Filippakopoulos, P, Keates, T, Picaud, S, Felletar, I, Pike, A.C.W, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-03-31 | 公開日 | 2011-06-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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2JHJ
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![BU of 2jhj by Molmil](/molmil-images/mine/2jhj) | 3-methyladenine dna-glycosylase from Archaeoglobus fulgidus | 分子名称: | 3-METHYLADENINE DNA-GLYCOSYLASE, GLYCEROL, SODIUM ION | 著者 | Leiros, I, Nabong, M.P, Grosvik, K, Ringvoll, J, Haugland, G.T, Uldal, L, Reite, K, Olsbu, I.K, Knaevelsrud, I, Moe, E, Andersen, O.A, Birkeland, N.K, Ruoff, P, Klungland, A, Bjelland, S. | 登録日 | 2007-02-22 | 公開日 | 2007-04-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA Embo J., 26, 2007
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4KNB
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![BU of 4knb by Molmil](/molmil-images/mine/4knb) | C-Met in complex with OSI ligand | 分子名称: | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor | 著者 | Wang, J, Steinig, A.G, Li, A.H, Chen, X, Dong, H, Ferraro, C, Jin, M, Kadalbajoo, M, Kleinberg, A, Stolz, K.M, Tavares-Greco, P.A, Wang, T, Albertella, M.R, Peng, Y, Crew, L, Kahler, J. | 登録日 | 2013-05-09 | 公開日 | 2014-04-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases. Bioorg.Med.Chem.Lett., 23, 2013
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2PZB
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![BU of 2pzb by Molmil](/molmil-images/mine/2pzb) | NAD+ Synthetase from Bacillus anthracis | 分子名称: | NH(3)-dependent NAD(+) synthetase, SULFATE ION | 著者 | McDonald, H.M, Pruett, P.S, Deivanayagam, C, Protasevich, I.I, Carson, W.M, DeLucas, L.J, Brouillette, W.J, Brouillette, C.G. | 登録日 | 2007-05-17 | 公開日 | 2007-07-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD(+) synthetase from Bacillus anthracis. Acta Crystallogr.,Sect.D, 63, 2007
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4ENP
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![BU of 4enp by Molmil](/molmil-images/mine/4enp) | Structure of E530A variant E. coli KatE | 分子名称: | Catalase HPII, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Loewen, P.C, Jha, V. | 登録日 | 2012-04-13 | 公開日 | 2012-05-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli. Arch.Biochem.Biophys., 526, 2012
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4KNX
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![BU of 4knx by Molmil](/molmil-images/mine/4knx) | Hin GlmU Bound to WG176 | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, SULFATE ION, ... | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | 登録日 | 2013-05-10 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22, 2014
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2PZY
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![BU of 2pzy by Molmil](/molmil-images/mine/2pzy) | Structure of MK2 Complexed with Compound 76 | 分子名称: | (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE | 著者 | White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B. | 登録日 | 2007-05-18 | 公開日 | 2007-07-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The discovery of carboline analogs as potent MAPKAP-K2 inhibitors Bioorg.Med.Chem.Lett., 17, 2007
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1ZSE
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![BU of 1zse by Molmil](/molmil-images/mine/1zse) | RNA stemloop from bacteriophage Qbeta complexed with an N87S mutant MS2 Capsid | 分子名称: | Coat protein, RNA HAIRPIN | 著者 | Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G. | 登録日 | 2005-05-24 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2 Structure, 14, 2006
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1Q51
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![BU of 1q51 by Molmil](/molmil-images/mine/1q51) | Crystal Structure of Mycobacterium tuberculosis MenB in Complex with Acetoacetyl-Coenzyme A, a Key Enzyme in Vitamin K2 Biosynthesis | 分子名称: | ACETOACETYL-COENZYME A, menB | 著者 | Truglio, J.J, Theis, K, Feng, Y, Gajda, R, Machutta, C, Tonge, P.J, Kisker, C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-05 | 公開日 | 2004-01-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis MenB, a key enzyme in vitamin K2 biosynthesis. J.Biol.Chem., 278, 2003
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4Q3E
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![BU of 4q3e by Molmil](/molmil-images/mine/4q3e) | PylD cocrystallized with L-Ornithine-Nd-D-lysine and NAD+ | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ... | 著者 | Quitterer, F, Beck, P, Bacher, A, Groll, M. | 登録日 | 2014-04-11 | 公開日 | 2014-04-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Formation of Pyrroline and Tetrahydropyridine Rings in Amino Acids Catalyzed by Pyrrolysine Synthase (PylD). Angew.Chem.Int.Ed.Engl., 53, 2014
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2JM2
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![BU of 2jm2 by Molmil](/molmil-images/mine/2jm2) | Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs | 分子名称: | Insulin-like growth factor-binding protein 6 | 著者 | Chandrashekaran, I.R, Yao, S, Wang, C.C, Bansal, P.S, Alewood, P.F, Forbes, B.E, Wallace, J.C, Bach, L.A, Norton, R.S. | 登録日 | 2006-09-18 | 公開日 | 2007-03-27 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The N-Terminal Subdomain of Insulin-like Growth Factor (IGF) Binding Protein 6. Structure and Interaction with IGFs Biochemistry, 46, 2007
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3H3U
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![BU of 3h3u by Molmil](/molmil-images/mine/3h3u) | Crystal structure of CRP (cAMP receptor Protein) from Mycobacterium tuberculosis | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY), SULFATE ION | 著者 | Kumar, P, Joshi, D.C, Akif, M, Akhter, Y, Hasnain, S.E, Mande, S.C. | 登録日 | 2009-04-17 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Mapping conformational transitions in cyclic AMP receptor protein: crystal structure and normal-mode analysis of Mycobacterium tuberculosis apo-cAMP receptor protein Biophys.J., 98, 2010
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7LGP
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![BU of 7lgp by Molmil](/molmil-images/mine/7lgp) | DapE enzyme from Shigella flexneri | 分子名称: | CHLORIDE ION, SODIUM ION, Succinyl-diaminopimelate desuccinylase, ... | 著者 | Osipiuk, J, Endres, M, Becker, D.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-01-20 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | DapE enzyme from Shigella flexneri To Be Published
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7LAO
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![BU of 7lao by Molmil](/molmil-images/mine/7lao) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IIb | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aminoglycoside N(3)-acetyltransferase III, MAGNESIUM ION | 著者 | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-01-06 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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2PIA
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![BU of 2pia by Molmil](/molmil-images/mine/2pia) | PHTHALATE DIOXYGENASE REDUCTASE: A MODULAR STRUCTURE FOR ELECTRON TRANSFER FROM PYRIDINE NUCLEOTIDES TO [2FE-2S] | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, PHTHALATE DIOXYGENASE REDUCTASE | 著者 | Correll, C.C, Batie, C.J, Ballou, D.P, Ludwig, M.L. | 登録日 | 1993-02-15 | 公開日 | 1993-04-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phthalate dioxygenase reductase: a modular structure for electron transfer from pyridine nucleotides to [2Fe-2S]. Science, 258, 1992
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2JM6
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![BU of 2jm6 by Molmil](/molmil-images/mine/2jm6) | Solution structure of MCL-1 complexed with NOXAB | 分子名称: | Myeloid cell leukemia-1 protein Mcl-1 homolog, Noxa | 著者 | Czabotar, P.E, Lee, E.F, van Delft, M.F, Day, C.L, Smith, B.J, Huang, D.C.S, Fairlie, W.D, Hinds, M.G, Colman, P.M. | 登録日 | 2006-10-17 | 公開日 | 2007-03-20 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insights into the degradation of Mcl-1 induced by BH3 domains Proc.Natl.Acad.Sci.Usa, 104, 2007
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4PVF
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![BU of 4pvf by Molmil](/molmil-images/mine/4pvf) | Crystal structure of Homo sapiens holo serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), isoform 3, transcript variant 5, 483 aa, at 2.6 ang. resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Serine hydroxymethyltransferase, ... | 著者 | Giardina, G, Brunotti, P, Fiascarelli, A, Contestabile, R, Cutruzzola, F. | 登録日 | 2014-03-17 | 公開日 | 2015-01-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state. Febs J., 282, 2015
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1JQI
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![BU of 1jqi by Molmil](/molmil-images/mine/1jqi) | Crystal Structure of Rat Short Chain Acyl-CoA Dehydrogenase Complexed With Acetoacetyl-CoA | 分子名称: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, short chain acyl-CoA dehydrogenase | 著者 | Battaile, K.P, Molin-Case, J, Paschke, R, Wang, M, Bennett, D, Vockley, J, Kim, J.-J.P. | 登録日 | 2001-08-07 | 公開日 | 2002-02-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases. J.Biol.Chem., 277, 2002
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