8GIJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gij by Molmil](/molmil-images/mine/8gij) | |
8GII
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gii by Molmil](/molmil-images/mine/8gii) | TEM-1 Beta Lactamase Variant 80.a | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TEM-1 Variant 80.a | Authors: | Fram, B.F, Gauthier, N.P, Khan, A.R, Sander, C. | Deposit date: | 2023-03-14 | Release date: | 2024-04-17 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun, 15, 2024
|
|
8DVD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dvd by Molmil](/molmil-images/mine/8dvd) | |
8OFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ofu by Molmil](/molmil-images/mine/8ofu) | Human adenovirus type 53 fiber-knob protein | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber protein, ... | Authors: | Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T. | Deposit date: | 2023-03-16 | Release date: | 2023-09-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Broad sialic acid usage amongst species D human adenovirus. Npj Viruses, 1, 2023
|
|
5KBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kbf by Molmil](/molmil-images/mine/5kbf) | cAMP bound PfPKA-R (141-441) | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit, putative | Authors: | Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. | Deposit date: | 2016-06-03 | Release date: | 2016-10-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
|
|
8JSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jsm by Molmil](/molmil-images/mine/8jsm) | The structure of EBOV L-VP35-RNA complex (conformation 1) | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
|
|
4CQQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cqq by Molmil](/molmil-images/mine/4cqq) | H5 (VN1194) Ser227Asn/Gln196Arg Mutant Haemagglutinin in Complex with Avian Receptor Analogue 3'SLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... | Authors: | Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Liu, J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2014-02-21 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Enhanced Human Receptor Binding by H5 Haemagglutinins. Virology, 456, 2014
|
|
8JSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jsl by Molmil](/molmil-images/mine/8jsl) | The structure of EBOV L-VP35-RNA complex | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
|
|
6C2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c2s by Molmil](/molmil-images/mine/6c2s) | Transcriptional repressor, CouR, bound to a 23-mer DNA duplex | Descriptor: | 23-mer, Transcriptional regulator, MarR family | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-01-08 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris. J. Biol. Chem., 293, 2018
|
|
8ECD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ecd by Molmil](/molmil-images/mine/8ecd) | E. coli L-asparaginase II mutant (V27T) in complex with L-Asp | Descriptor: | 1,2-ETHANEDIOL, ASPARTIC ACID, CITRIC ACID, ... | Authors: | Strzelczyk, P, Wlodawer, A, Lubkowski, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The E. coli L-asparaginase V27T mutant: structural and functional characterization and comparison with theoretical predictions. Febs Lett., 596, 2022
|
|
6TAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tac by Molmil](/molmil-images/mine/6tac) | Human NAMPT deletion mutant in complex with nicotinamide mononucleotide, pyrophosphate, and Mg2+ | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Houry, D, Raasakka, A, Kursula, P, Ziegler, M. | Deposit date: | 2019-10-29 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification of structural determinants of NAMPT activity and substrate selectivity To Be Published
|
|
5GRS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5grs by Molmil](/molmil-images/mine/5grs) | Complex structure of the fission yeast SREBP-SCAP binding domains | Descriptor: | Sterol regulatory element-binding protein 1, Sterol regulatory element-binding protein cleavage-activating protein | Authors: | Gong, X, Qian, H.W, Wu, J.P, Yan, N. | Deposit date: | 2016-08-12 | Release date: | 2016-12-14 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization Cell Res., 26, 2016
|
|
2WKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wkl by Molmil](/molmil-images/mine/2wkl) | Velaglucerase alfa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUCOSYLCERAMIDASE, ... | Authors: | Brumshtein, B, Salinas, P, Peterson, B, Chan, V, Silman, I, Sussman, J.L, Savickas, P.J, Robinson, G.S, Futerman, A.H. | Deposit date: | 2009-06-15 | Release date: | 2009-09-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Characterization of Gene-Activated Human Acid-Beta-Glucosidase: Crystal Structure, Glycan Composition and Internalization Into Macrophages. Glycobiology, 20, 2010
|
|
8JSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jsn by Molmil](/molmil-images/mine/8jsn) | The structure of EBOV L-VP35-RNA complex (conformation 2) | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
|
|
6FCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6fci by Molmil](/molmil-images/mine/6fci) | Crystal Structure of Human APRT wild type in complex with Adenine, PRPP and Mg2+ | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENINE, Adenine phosphoribosyltransferase, ... | Authors: | Nioche, P, Huyet, J, Ozeir, M. | Deposit date: | 2017-12-20 | Release date: | 2018-08-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase. Cell Chem Biol, 25, 2018
|
|
6BYG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6byg by Molmil](/molmil-images/mine/6byg) | Crystal structure of the nucleophile mutant (E575A) of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri | Descriptor: | Beta-mannosidase, beta-D-mannopyranose | Authors: | Domingues, M.N, Vieira, P.S, Morais, M.A.B, Murakami, M.T. | Deposit date: | 2017-12-20 | Release date: | 2018-07-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Structural basis of exo-beta-mannanase activity in the GH2 family. J. Biol. Chem., 293, 2018
|
|
3G6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g6e by Molmil](/molmil-images/mine/3g6e) | Co-crystal structure of Homoharringtonine bound to the large ribosomal subunit | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 23S ribosomal RNA, 50S ribosomal protein L10E, ... | Authors: | Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A. | Deposit date: | 2009-02-06 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J.Mol.Biol., 389, 2009
|
|
1NHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nhx by Molmil](/molmil-images/mine/1nhx) | PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, N-{4-[1-(2-FLUOROBENZYL)-3-BUTYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YLMETHYL]-PHENYL}-ACETAMIDE, ... | Authors: | Foley, L.H, Wang, P, Dunten, P, Ramsey, G, Gubler, M.-L, Wertheimer, S.J. | Deposit date: | 2002-12-19 | Release date: | 2003-09-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
|
|
3GC1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gc1 by Molmil](/molmil-images/mine/3gc1) | Crystal structure of bovine lactoperoxidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, IODIDE ION, ... | Authors: | Singh, A.K, Singh, N, Sinha, M, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P. | Deposit date: | 2009-02-21 | Release date: | 2009-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mode of binding of the tuberculosis prodrug isoniazid to heme peroxidases: binding studies and crystal structure of bovine lactoperoxidase with isoniazid at 2.7 A resolution. J.Biol.Chem., 285, 2010
|
|
3JVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jvo by Molmil](/molmil-images/mine/3jvo) | Crystal structure of bacteriophage HK97 gp6 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Gp6 | Authors: | Lam, R, Tuite, A, Battaile, K.P, Edwards, A.M, Maxwell, K.L, Chirgadze, N.Y. | Deposit date: | 2009-09-17 | Release date: | 2009-11-24 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of bacteriophage HK97 gp6: defining a large family of head-tail connector proteins. J.Mol.Biol., 395, 2010
|
|
4R31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r31 by Molmil](/molmil-images/mine/4r31) | |
5SXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5sxs by Molmil](/molmil-images/mine/5sxs) | |
3X11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x11 by Molmil](/molmil-images/mine/3x11) | Crystal structure of HLA-B*57:01.I80N.L82R.R83G | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | Authors: | Vivian, J.P, Rossjohn, J. | Deposit date: | 2014-10-24 | Release date: | 2014-12-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope J.Immunol., 194, 2015
|
|
6JXM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jxm by Molmil](/molmil-images/mine/6jxm) | Crystal Structure of phi29 pRNA domain II | Descriptor: | BARIUM ION, MAGNESIUM ION, RNA (97-mer) | Authors: | Cai, R, Price, I.R, Ding, F, Wu, F, Chen, T, Zhang, Y, Liu, G, Jardine, P.J, Lu, C, Ke, A. | Deposit date: | 2019-04-24 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor. Nucleic Acids Res., 47, 2019
|
|
4CQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cqz by Molmil](/molmil-images/mine/4cqz) | Crystal Structure of H5 (VN1194) Gln196Arg Mutant Haemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, J, Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2014-02-21 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Enhanced Human Receptor Binding by H5 Haemagglutinins. Virology, 456, 2014
|
|