5BCA
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![BU of 5bca by Molmil](/molmil-images/mine/5bca) | BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES | Descriptor: | CALCIUM ION, PROTEIN (1,4-ALPHA-D-GLUCAN MALTOHYDROLASE.) | Authors: | Oyama, T, Kusunoki, M, Kishimoto, Y, Takasaki, Y, Nitta, Y. | Deposit date: | 1999-03-12 | Release date: | 2000-03-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of beta-amylase from Bacillus cereus var. mycoides at 2.2 A resolution. J.Biochem.(Tokyo), 125, 1999
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5GHS
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![BU of 5ghs by Molmil](/molmil-images/mine/5ghs) | DNA replication protein | Descriptor: | Putative uncharacterized protein, SULFATE ION, SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.591 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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5GHR
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![BU of 5ghr by Molmil](/molmil-images/mine/5ghr) | DNA replication protein | Descriptor: | Putative uncharacterized protein, SULFATE ION, SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.509 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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5GHT
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![BU of 5ght by Molmil](/molmil-images/mine/5ght) | DNA replication protein | Descriptor: | SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.795 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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4YT1
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![BU of 4yt1 by Molmil](/molmil-images/mine/4yt1) | Human PPAR Gamma Ligand Binding Domain in complex with a Gammma Selective Synthetic Partial Agonist MEKT76 | Descriptor: | N-(benzylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Miyachi, H, Kusunoki, M. | Deposit date: | 2015-03-17 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Peroxisome proliferator-activated receptor gamma (PPAR gamma ) has multiple binding points that accommodate ligands in various conformations: Structurally similar PPAR gamma partial agonists bind to PPAR gamma LBD in different conformations Bioorg.Med.Chem.Lett., 25, 2015
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7VWF
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![BU of 7vwf by Molmil](/molmil-images/mine/7vwf) | |
7VWG
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![BU of 7vwg by Molmil](/molmil-images/mine/7vwg) | |
7VWH
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![BU of 7vwh by Molmil](/molmil-images/mine/7vwh) | |
7VWE
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![BU of 7vwe by Molmil](/molmil-images/mine/7vwe) | |
7E15
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![BU of 7e15 by Molmil](/molmil-images/mine/7e15) | |
7E5F
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![BU of 7e5f by Molmil](/molmil-images/mine/7e5f) | HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH TIPP703 OBTAINED BY SOAKING | Descriptor: | (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Oyama, T, Kamata, S, Ishii, I, Miyachi, H. | Deposit date: | 2021-02-18 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
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7E5G
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![BU of 7e5g by Molmil](/molmil-images/mine/7e5g) | HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH YN4pai OBTAINED BY SOAKING | Descriptor: | (2S)-2-[[4-butoxy-3-[(pyren-1-ylcarbonylamino)methyl]phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Oyama, T, Kamata, S, Ishii, I, Miyachi, H. | Deposit date: | 2021-02-18 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
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7E5I
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![BU of 7e5i by Molmil](/molmil-images/mine/7e5i) | HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY SOAKING | Descriptor: | (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Oyama, T, Kamata, S, Ishii, I, Miyachi, H. | Deposit date: | 2021-02-18 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
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7E5H
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![BU of 7e5h by Molmil](/molmil-images/mine/7e5h) | HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH APHM6 OBTAINED BY COCRYSTALLIZATION | Descriptor: | (2S)-2-[[3-[[3-fluoranyl-4-(4-fluoranylphenoxy)phenyl]methylcarbamoyl]-4-methoxy-phenyl]methyl]butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Oyama, T, Kamata, S, Ishii, I, Miyachi, H. | Deposit date: | 2021-02-18 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal Structures of the Human Peroxisome Proliferator-Activated Receptor (PPAR) alpha Ligand-Binding Domain in Complexes with a Series of Phenylpropanoic Acid Derivatives Generated by a Ligand-Exchange Soaking Method. Biol.Pharm.Bull., 44, 2021
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3ANW
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![BU of 3anw by Molmil](/molmil-images/mine/3anw) | A protein complex essential initiation of DNA replication | Descriptor: | Putative uncharacterized protein | Authors: | Oyama, T, Shirai, T, Nagasawa, N, Ishino, Y, Morikawa, K. | Deposit date: | 2010-09-10 | Release date: | 2011-07-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Architectures of archaeal GINS complexes, essential DNA replication initiation factors Bmc Biol., 9, 2011
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3AN4
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![BU of 3an4 by Molmil](/molmil-images/mine/3an4) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R | Descriptor: | (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
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3AN3
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![BU of 3an3 by Molmil](/molmil-images/mine/3an3) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO3S | Descriptor: | (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
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1J10
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![BU of 1j10 by Molmil](/molmil-images/mine/1j10) | beta-amylase from Bacillus cereus var. mycoides in complex with GGX | Descriptor: | Beta-amylase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-xylopyranose, ... | Authors: | Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y. | Deposit date: | 2002-11-25 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents J.BIOCHEM.(TOKYO), 133, 2003
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1J11
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![BU of 1j11 by Molmil](/molmil-images/mine/1j11) | beta-amylase from Bacillus cereus var. mycoides in complex with alpha-EPG | Descriptor: | (2R)-oxiran-2-ylmethyl alpha-D-glucopyranoside, Beta-amylase, CALCIUM ION | Authors: | Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y. | Deposit date: | 2002-11-25 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents J.BIOCHEM.(TOKYO), 133, 2003
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1J0Z
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![BU of 1j0z by Molmil](/molmil-images/mine/1j0z) | Beta-amylase from Bacillus cereus var. mycoides in complex with maltose | Descriptor: | Beta-amylase, CALCIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y. | Deposit date: | 2002-11-25 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents J.BIOCHEM.(TOKYO), 133, 2003
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1J0Y
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![BU of 1j0y by Molmil](/molmil-images/mine/1j0y) | Beta-amylase from Bacillus cereus var. mycoides in complex with glucose | Descriptor: | Beta-amylase, CALCIUM ION, beta-D-glucopyranose | Authors: | Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y. | Deposit date: | 2002-11-25 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents J.BIOCHEM.(TOKYO), 133, 2003
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1J12
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![BU of 1j12 by Molmil](/molmil-images/mine/1j12) | Beta-Amylase from Bacillus cereus var. mycoides in Complex with alpha-EBG | Descriptor: | 2-[(2S)-oxiran-2-yl]ethyl alpha-D-glucopyranoside, Beta-amylase, CALCIUM ION | Authors: | Oyama, T, Miyake, H, Kusunoki, M, Nitta, Y. | Deposit date: | 2002-11-25 | Release date: | 2003-06-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents J.BIOCHEM.(TOKYO), 133, 2003
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1IQP
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![BU of 1iqp by Molmil](/molmil-images/mine/1iqp) | Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RFCS | Authors: | Oyama, T, Ishino, Y, Cann, I.K.O, Ishino, S, Morikawa, K. | Deposit date: | 2001-07-24 | Release date: | 2001-09-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus Mol.Cell, 8, 2001
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2ZNO
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![BU of 2zno by Molmil](/molmil-images/mine/2zno) | Human PPAR gamma ligand binding domain in complex with a synthetic agonist TIPP703 | Descriptor: | (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Waku, T, Kasuga, J, Miyachi, H, Morikawa, K. | Deposit date: | 2008-04-30 | Release date: | 2009-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures Acta Crystallogr.,Sect.D, 65, 2009
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2ZNN
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![BU of 2znn by Molmil](/molmil-images/mine/2znn) | Human PPAR alpha ligand binding domain in complex with a synthetic agonist TIPP703 | Descriptor: | (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Oyama, T, Toyota, K, Kasuga, J, Miyachi, H, Morikawa, K. | Deposit date: | 2008-04-30 | Release date: | 2009-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures Acta Crystallogr.,Sect.D, 65, 2009
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