4DKS
| A spindle-shaped virus protein (chymotrypsin treated) | Descriptor: | Probable integrase | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | Deposit date: | 2012-02-04 | Release date: | 2012-05-30 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase. Acta Crystallogr.,Sect.D, 68, 2012
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6KUE
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6KL4
| Crystal structure of MavC-UBE2N-Ub | Descriptor: | MavC, Ub, Ubiquitin-conjugating enzyme E2 N | Authors: | Ouyang, S, Guan, H. | Deposit date: | 2019-07-29 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC. Adv Sci, 7, 2020
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6KWY
| human PA200-20S complex | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | Authors: | Ouyang, S, Hongxin, G. | Deposit date: | 2019-09-09 | Release date: | 2020-04-01 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures. Plos Biol., 18, 2020
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6KWX
| cryo-EM structure of human PA200 | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, [(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-[oxidanyl(phosphonooxy)phosphoryl]oxy-3,4,5,6-tetraphosphonooxy-cyclohexyl] phosphono hydrogen phosphate | Authors: | Ouyang, S, Hongxin, G. | Deposit date: | 2019-09-09 | Release date: | 2020-04-01 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures. Plos Biol., 18, 2020
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8IPJ
| Crystal structure of the Legionella effector protein MavL with ADPR-Ub | Descriptor: | MavL, Ubiquitin, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Ouyang, S, Guan, H. | Deposit date: | 2023-03-14 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Crystal structure of the Legionella effector protein MavL with ADPR-Ub To Be Published
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8IPW
| The sturecture of Legionella effector protein MavL with ADPR | Descriptor: | MavL, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Ouyang, S, Hongxin, G. | Deposit date: | 2023-03-15 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The sturecture of Legionella effector protein MavL with ADPR To Be Published
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3VCF
| SSV1 integrase C-terminal catalytic domain (174-335aa) | Descriptor: | Probable integrase | Authors: | Ouyang, S, Liang, W, Huang, L, Liu, Z.-J. | Deposit date: | 2012-01-04 | Release date: | 2012-05-30 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase. Acta Crystallogr.,Sect.D, 68, 2012
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3UX9
| Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus | Descriptor: | Interferon alpha-1/13, ScFv antibody | Authors: | Ouyang, S, Zhao, L.X, Liang, W, Shaw, N, Liu, Z.-J, Liang, M.-F. | Deposit date: | 2011-12-04 | Release date: | 2012-02-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus J.Mol.Med., 2012
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4WYH
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4EF4
| Crystal structure of STING CTD complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 | Authors: | Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J. | Deposit date: | 2012-03-29 | Release date: | 2012-05-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.147 Å) | Cite: | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding Immunity, 36, 2012
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4EF5
| Crystal structure of STING CTD | Descriptor: | Transmembrane protein 173 | Authors: | Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J. | Deposit date: | 2012-03-29 | Release date: | 2012-05-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding Immunity, 36, 2012
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5FAD
| SAH complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicus | Descriptor: | MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ... | Authors: | Ouyang, S. | Deposit date: | 2015-12-11 | Release date: | 2016-06-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism Mol.Cell Proteomics, 15, 2016
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5FA8
| SAM complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicu | Descriptor: | MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ... | Authors: | Ouyang, S. | Deposit date: | 2015-12-11 | Release date: | 2016-06-29 | Last modified: | 2016-09-14 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism Mol.Cell Proteomics, 15, 2016
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6M39
| Cryo-EM structure of SADS-CoV spike | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Ouyang, S, Hongxin, G. | Deposit date: | 2020-03-03 | Release date: | 2020-08-26 | Last modified: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Cryo-electron Microscopy Structure of the Swine Acute Diarrhea Syndrome Coronavirus Spike Glycoprotein Provides Insights into Evolution of Unique Coronavirus Spike Proteins. J.Virol., 94, 2020
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7W3S
| The complex structure of Larg1-ADPr from Legionella pneumophila | Descriptor: | Type IV secretion protein Dot, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Ouyang, S, Guan, H, Li, P. | Deposit date: | 2021-11-26 | Release date: | 2022-04-06 | Last modified: | 2022-05-18 | Method: | X-RAY DIFFRACTION (2.324 Å) | Cite: | Legionella pneumophila temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation. mLife, 2022
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7WQY
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6K1T
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6K11
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7DMS
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5EFX
| Crystal structure of Rho GTPase regulator | Descriptor: | Rho guanine nucleotide exchange factor 2 | Authors: | Jiang, Y, Ouyang, S, Liu, Z.J. | Deposit date: | 2015-10-26 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.451 Å) | Cite: | Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding Biochem.Biophys.Res.Commun., 471, 2016
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4M4E
| TRAF domain of human TRAF4 | Descriptor: | TNF receptor-associated factor 4 | Authors: | Niu, F, Ru, H, Ding, W, Ouyang, S, Liu, Z.J. | Deposit date: | 2013-08-07 | Release date: | 2013-09-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural biology study of human TNF receptor associated factor 4 TRAF domain Protein Cell, 4, 2013
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7WXZ
| Crystal structure of the recombinant protein HR121 from the S2 protein of SARS-CoV-2 | Descriptor: | Spike protein S2' | Authors: | Zheng, Y.T, Ouyang, S, Pang, W, Lu, Y, Zhao, Y.B. | Deposit date: | 2022-02-15 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein. Cell Res., 32, 2022
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5D39
| Transcription factor-DNA complex | Descriptor: | DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*GP*GP*AP*AP*GP*AP*CP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*TP*CP*TP*TP*CP*CP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), Signal transducer and activator of transcription 6 | Authors: | Li, J, Niu, F, Ouyang, S, Liu, Z. | Deposit date: | 2015-08-06 | Release date: | 2016-08-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for DNA recognition by STAT6 Proc.Natl.Acad.Sci.USA, 113, 2016
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4Y5U
| Transcription factor | Descriptor: | NICKEL (II) ION, Signal transducer and activator of transcription 6 | Authors: | Li, J, Niu, F, Ouyang, S, Liu, Z. | Deposit date: | 2015-02-12 | Release date: | 2016-02-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.708 Å) | Cite: | Structural basis for DNA recognition by STAT6 Proc.Natl.Acad.Sci.USA, 113, 2016
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