1SL4
 
 | | Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with Man4 | | 分子名称: | CALCIUM ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, mDC-SIGN1B type I isoform | | 著者 | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | | 登録日 | 2004-03-05 | | 公開日 | 2004-06-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
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1SM7
 | | Solution structure of the recombinant pronapin precursor, BnIb. | | 分子名称: | recombinant Ib pronapin | | 著者 | Pantoja-Uceda, D, Palomares, O, Bruix, M, Villalba, M, Rodriguez, R, Rico, M, Santoro, J. | | 登録日 | 2004-03-08 | | 公開日 | 2005-02-01 | | 最終更新日 | 2013-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and stability against digestion of rproBnIb, a recombinant 2S albumin from rapeseed: relationship to its allergenic properties.
Biochemistry, 43, 2004
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7PV0
 | | Crystal structure of a Mic60-Mic19 fusion protein | | 分子名称: | MICOS complex subunit MIC60,MICOS complex subunit MIC60-MIC19,Mic60-Mic19, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) | | 著者 | Funck, K, Bock-Bierbaum, T, Daumke, O. | | 登録日 | 2021-10-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into crista junction formation by the Mic60-Mic19 complex.
Sci Adv, 8, 2022
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1S2V
 | | Crystal structure of phosphoenolpyruvate mutase complexed with Mg(II) | | 分子名称: | MAGNESIUM ION, Phosphoenolpyruvate phosphomutase | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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4R81
 | | NAD(P)H:quinone oxidoreductase from Methanothermobacter marburgensis | | 分子名称: | FLAVIN MONONUCLEOTIDE, NADH dehydrogenase | | 著者 | Ullmann, E, Tan, T.C, Herwig, C, Divne, C, Spadiut, O. | | 登録日 | 2014-08-29 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis.
Biosci.Rep., 34, 2014
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7PSP
 | | Crystal structure of S100A4 labeled with NU000846b. | | 分子名称: | (2R,4R)-1-(2-chloranylethanoyl)-N-(3-chlorophenyl)-4-phenyl-pyrrolidine-2-carboxamide, CALCIUM ION, Protein S100-A4 | | 著者 | Giroud, C, Szommer, T, Coxon, C, Monteiro, O, Christott, T, Bennett, J, Aitmakhanova, K, Raux, B, Newman, J, Elkins, J, Arruda Bezerra, G, Krojer, T, Koekemoer, L, Von Delft, F, Bountr, C, Brennan, P, Fedorov, O. | | 登録日 | 2021-09-23 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structure of S100A4 labeled with NU000846b.
To Be Published
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4R1Y
 | | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitor | | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 3-(diethylamino)propyl (3-{[5-(3,4-dimethoxyphenyl)-2-oxo-2H-1,3,4-thiadiazin-3(6H)-yl]methyl}phenyl)carbamate, Hepatocyte growth factor receptor | | 著者 | Blaukat, A, Bladt, F, Friese-Hamim, M, Knuehl, C, Fittschen, C, Graedler, U, Meyring, M, Dorsch, D, Stieber, F, Schadt, O. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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1SEH
 | | Crystal structure of E. coli dUTPase complexed with the product dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase | | 著者 | Barabas, O, Kovari, J, Pongracz, V, Wilmanns, M, Vertessy, B.G. | | 登録日 | 2004-02-17 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase
J.Biol.Chem., 279, 2004
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1SC8
 | | Urokinase Plasminogen Activator B-Chain-J435 Complex | | 分子名称: | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}GLYCINAMIDE, SULFATE ION, plasminogen activator, ... | | 著者 | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | | 登録日 | 2004-02-12 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
J.Biol.Chem., 279, 2004
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4RA7
 | | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with nafcillin | | 分子名称: | (2R,4S)-2-[(1R)-2-hydroxy-1-{[(2-hydroxynaphthalen-1-yl)carbonyl]amino}ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Peptidoglycan glycosyltransferase | | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-09-09 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum in complex with nafcillin
To be Published
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4RFA
 | | Crystal structure of cyclic nucleotide-binding domain containing protein from Listeria monocytogenes EGD-e | | 分子名称: | Lmo0740 protein | | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-09-25 | | 公開日 | 2014-10-15 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structure of cyclic nucleotide-binding domain containing protein from Listeria monocytogenes EGD-e
To be Published
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4QXU
 | | Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody | | 分子名称: | Matrix metalloproteinase-14, SULFATE ION, anti_MT1-MMP Heavy chain, ... | | 著者 | Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Moreno, v, Cuiniasse, P, Dive, V, Arroyo, A.G, Sagi, I, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2014-07-22 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure, 23, 2015
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7Q3I
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1SL6
 | | Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x. | | 分子名称: | C-type lectin DC-SIGNR, CALCIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose | | 著者 | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | | 登録日 | 2004-03-05 | | 公開日 | 2004-06-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
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1SCF
 | | HUMAN RECOMBINANT STEM CELL FACTOR | | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, STEM CELL FACTOR | | 著者 | Jiang, X, Gurel, O, Langley, K.E, Hendrickson, W.A. | | 登録日 | 1998-06-04 | | 公開日 | 2000-07-07 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.
EMBO J., 19, 2000
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7QCQ
 | | VHH Z70 in interaction with PHF6 Tau peptide | | 分子名称: | GLYCEROL, Tau 301-312, VHH Z70 | | 著者 | Danis, C, Dupre, E, Zejneli, O, Caillierez, R, Arrial, A, Begard, S, Loyens, A, Mortelecque, J, Cantrelle, F.-X, Hanoulle, X, Rain, J.-C, Colin, M, Buee, L, Landrieu, I. | | 登録日 | 2021-11-25 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Mol.Ther., 30, 2022
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1SLT
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1SQE
 | | 1.5A Crystal Structure Of the protein PG130 from Staphylococcus aureus, Structural genomics | | 分子名称: | hypothetical protein PG130 | | 著者 | Zhang, R, Wu, R, Joachimiak, G, Schneewind, O, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-03-18 | | 公開日 | 2004-08-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases
J.Biol.Chem., 280, 2005
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7QBU
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBT
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, FE (III) ION, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBS
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, S-adenosyl-L-methionine, and peptide bound. | | 分子名称: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | 著者 | Bernardo-Garcia, N, Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.327 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBV
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-adenosyl-L-homocysteine bound. | | 分子名称: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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1SUV
 | | Structure of Human Transferrin Receptor-Transferrin Complex | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin, ... | | 著者 | Cheng, Y, Zak, O, Aisen, P, Harrison, S.C, Walz, T. | | 登録日 | 2004-03-26 | | 公開日 | 2004-04-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Structure of the Human Transferrin Receptor-Transferrin Complex
Cell(Cambridge,Mass.), 116, 2004
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4RFV
 | | Structure of the Mycobacterium tuberculosis APS kinase CysC Cys556Ala mutant | | 分子名称: | Bifunctional enzyme CysN/CysC, PHOSPHATE ION | | 著者 | Poyraz, O, Brunner, K, Schnell, R, Schneider, G. | | 登録日 | 2014-09-28 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystal Structures of the Kinase Domain of the Sulfate-Activating Complex in Mycobacterium tuberculosis.
Plos One, 10, 2015
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7QH4
 | | Structure of the B. subtilis disome - collided 70S ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | | 登録日 | 2021-12-10 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (5.45 Å) | | 主引用文献 | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
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