1SEH

Crystal structure of E. coli dUTPase complexed with the product dUMP

Summary for 1SEH

Entry DOI	10.2210/pdb1seh/pdb
Related	1RN8 1RNJ 1RO1 1SYL
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	enzyme-ligand complex, jelly roll, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	16732.94
Authors	Barabas, O.,Kovari, J.,Pongracz, V.,Wilmanns, M.,Vertessy, B.G. (deposition date: 2004-02-17, release date: 2004-09-07, Last modification date: 2023-10-25)
Primary citation	Barabas, O.,Pongracz, V.,Kovari, J.,Wilmanns, M.,Vertessy, B.G. Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase J.Biol.Chem., 279:42907-42915, 2004 Cited by PubMed: 15208312 DOI: 10.1074/jbc.M406135200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation