1WY5
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![BU of 1wy5 by Molmil](/molmil-images/mine/1wy5) | Crystal structure of isoluecyl-tRNA lysidine synthetase | Descriptor: | Hypothetical UPF0072 protein AQ_1887 | Authors: | Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-02-06 | Release date: | 2005-05-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4UP7
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![BU of 4up7 by Molmil](/molmil-images/mine/4up7) | |
4UPA
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![BU of 4upa by Molmil](/molmil-images/mine/4upa) | |
4UP8
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![BU of 4up8 by Molmil](/molmil-images/mine/4up8) | |
4UP9
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![BU of 4up9 by Molmil](/molmil-images/mine/4up9) | |
3G5S
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![BU of 3g5s by Molmil](/molmil-images/mine/3g5s) | Crystal structure of Thermus thermophilus TrmFO in complex with glutathione | Descriptor: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, ... | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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1QQT
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![BU of 1qqt by Molmil](/molmil-images/mine/1qqt) | METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI | Descriptor: | METHIONYL-TRNA SYNTHETASE, ZINC ION | Authors: | Mechulam, Y, Schmitt, E, Maveyraud, L, Zelwer, C, Nureki, O, Yokoyama, S, Konno, M, Blanquet, S. | Deposit date: | 1999-06-08 | Release date: | 2000-01-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features. J.Mol.Biol., 294, 1999
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3G5Q
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![BU of 3g5q by Molmil](/molmil-images/mine/3g5q) | Crystal structure of Thermus thermophilus TrmFO | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5R
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![BU of 3g5r by Molmil](/molmil-images/mine/3g5r) | Crystal structure of Thermus thermophilus TrmFO in complex with tetrahydrofolate | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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7CJ3
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![BU of 7cj3 by Molmil](/molmil-images/mine/7cj3) | Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL | Authors: | Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. | Deposit date: | 2020-07-09 | Release date: | 2020-11-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
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8XBH
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![BU of 8xbh by Molmil](/molmil-images/mine/8xbh) | Human GPR34 -Gi complex bound to M1 | Descriptor: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Kawahara, R, Shihoya, W, Nureki, O. | Deposit date: | 2023-12-06 | Release date: | 2023-12-27 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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8XBE
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![BU of 8xbe by Molmil](/molmil-images/mine/8xbe) | Human GPR34 -Gi complex bound to S3E-LysoPS | Descriptor: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[(~{Z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Kawahara, R, Shihoya, W, Nureki, O. | Deposit date: | 2023-12-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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8XGR
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![BU of 8xgr by Molmil](/molmil-images/mine/8xgr) | ETB-eGt complex bound to endothelin-1 | Descriptor: | Camelid antibody VHH fragment, Endothelin receptor type B, Endothelin-1, ... | Authors: | Oshima, H.S, Sano, F.K, Akasaka, H, Iwama, A, Shihoya, W, Nureki, O. | Deposit date: | 2023-12-15 | Release date: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Optimizing cryo-EM structural analysis of G i -coupling receptors via engineered G t and Nb35 application. Biochem.Biophys.Res.Commun., 693, 2024
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4L3O
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![BU of 4l3o by Molmil](/molmil-images/mine/4l3o) | Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NAD-dependent protein deacetylase sirtuin-2, ... | Authors: | Yamagata, K, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2013-06-06 | Release date: | 2014-02-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.518 Å) | Cite: | Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change Structure, 22, 2013
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8ZJF
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![BU of 8zjf by Molmil](/molmil-images/mine/8zjf) | Cryo-EM structure of human integrin alpha-E beta-7 | Descriptor: | CALCIUM ION, Integrin alpha-E, Integrin beta-7, ... | Authors: | Akasaka, H, Nureki, O, Kise, Y. | Deposit date: | 2024-05-14 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structure of I domain-containing integrin alpha E beta 7. Biochem.Biophys.Res.Commun., 721, 2024
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4MKP
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![BU of 4mkp by Molmil](/molmil-images/mine/4mkp) | Crystal structure of human cGAS apo form | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Kato, K, Ishii, R, Ishitani, R, Nureki, O. | Deposit date: | 2013-09-05 | Release date: | 2013-10-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.953 Å) | Cite: | Structural and Functional Analyses of DNA-Sensing and Immune Activation by Human cGAS Plos One, 8, 2013
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4N0H
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![BU of 4n0h by Molmil](/molmil-images/mine/4n0h) | Crystal structure of S. cerevisiae mitochondrial GatFAB | Descriptor: | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glutamyl-tRNA(Gln) amidotransferase subunit B, ... | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | Deposit date: | 2013-10-02 | Release date: | 2014-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases Nucleic Acids Res., 42, 2014
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4KPP
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![BU of 4kpp by Molmil](/molmil-images/mine/4kpp) | Crystal Structure of H+/Ca2+ Exchanger CAX | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, OLEIC ACID, ... | Authors: | Nishizawa, T, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-14 | Release date: | 2013-06-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger. Science, 341, 2013
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4N0I
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![BU of 4n0i by Molmil](/molmil-images/mine/4n0i) | Crystal structure of S. cerevisiae mitochondrial GatFAB in complex with glutamine | Descriptor: | GLUTAMINE, Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, ... | Authors: | Araiso, Y, Ishitani, R, Nureki, O. | Deposit date: | 2013-10-02 | Release date: | 2014-04-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases Nucleic Acids Res., 42, 2014
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8XBG
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![BU of 8xbg by Molmil](/molmil-images/mine/8xbg) | |
8WUT
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![BU of 8wut by Molmil](/molmil-images/mine/8wut) | SpCas9-MMLV RT-pegRNA-target DNA complex (initiation) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2023-10-21 | Release date: | 2024-06-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8WUS
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![BU of 8wus by Molmil](/molmil-images/mine/8wus) | SpCas9-MMLV RT-pegRNA-target DNA complex (termination) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2023-10-21 | Release date: | 2024-06-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8WUU
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![BU of 8wuu by Molmil](/molmil-images/mine/8wuu) | SpCas9-pegRNA-target DNA complex (pre-initiation) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2023-10-21 | Release date: | 2024-06-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8WUV
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![BU of 8wuv by Molmil](/molmil-images/mine/8wuv) | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt) | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ... | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | Deposit date: | 2023-10-21 | Release date: | 2024-06-05 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8XBI
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![BU of 8xbi by Molmil](/molmil-images/mine/8xbi) | Human GPR34 -Gi complex bound to M1, receptor focused | Descriptor: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Probable G-protein coupled receptor 34 | Authors: | Kawahara, R, Shihoya, W, Nureki, O. | Deposit date: | 2023-12-06 | Release date: | 2023-12-27 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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