1B7F
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![BU of 1b7f by Molmil](/molmil-images/mine/1b7f) | SXL-LETHAL PROTEIN/RNA COMPLEX | Descriptor: | PROTEIN (SXL-LETHAL PROTEIN), RNA (5'-R(P*GP*UP*UP*GP*UP*UP*UP*UP*UP*UP*UP*U)-3') | Authors: | Handa, N, Nureki, O, Kurimoto, K, Kim, I, Sakamoto, H, Shimura, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1999-01-23 | Release date: | 1999-05-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein. Nature, 398, 1999
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5JYJ
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![BU of 5jyj by Molmil](/molmil-images/mine/5jyj) | Crystal structure of mouse JUNO | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sperm-egg fusion protein Juno | Authors: | Kato, K, Nishimasu, H, Morita, J, Ishitani, R, Nureki, O. | Deposit date: | 2016-05-14 | Release date: | 2017-05-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the egg IZUMO1 receptor JUNO To Be Published
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8JF0
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![BU of 8jf0 by Molmil](/molmil-images/mine/8jf0) | |
4GEL
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![BU of 4gel by Molmil](/molmil-images/mine/4gel) | Crystal structure of Zucchini | Descriptor: | 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, PHOSPHATE ION, ... | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-02 | Release date: | 2012-10-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.756 Å) | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
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4GEN
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![BU of 4gen by Molmil](/molmil-images/mine/4gen) | Crystal structure of Zucchini (monomer) | Descriptor: | CHLORIDE ION, Mitochondrial cardiolipin hydrolase | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-02 | Release date: | 2012-10-17 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
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4GEM
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![BU of 4gem by Molmil](/molmil-images/mine/4gem) | Crystal structure of Zucchini (K171A) | Descriptor: | 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, ZINC ION | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | Deposit date: | 2012-08-02 | Release date: | 2012-10-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis Nature, 491, 2012
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7YTB
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![BU of 7ytb by Molmil](/molmil-images/mine/7ytb) | Crystal structure of Kin4B8 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Kin4B8, RETINAL | Authors: | Murakoshi, S, Chazan, A, Shihoya, W, Beja, O, Nureki, O. | Deposit date: | 2022-08-14 | Release date: | 2023-03-15 | Last modified: | 2023-03-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature, 615, 2023
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1JZQ
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![BU of 1jzq by Molmil](/molmil-images/mine/1jzq) | Isoleucyl-tRNA synthetase Complexed with Isoleucyl-adenylate analogue | Descriptor: | Isoleucyl-tRNA synthetase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ZINC ION | Authors: | Nakama, T, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-09-17 | Release date: | 2001-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. J.Biol.Chem., 276, 2001
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8I2Z
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![BU of 8i2z by Molmil](/molmil-images/mine/8i2z) | Cryo-EM structure of the zeaxanthin-bound kin4B8 | Descriptor: | RETINAL, Xanthorhodopsin, Zeaxanthin | Authors: | Murakoshi, S, Chazan, A, Shihoya, W, Beja, O, Nureki, O. | Deposit date: | 2023-01-15 | Release date: | 2023-03-29 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature, 615, 2023
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1JZS
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![BU of 1jzs by Molmil](/molmil-images/mine/1jzs) | Isoleucyl-tRNA synthetase Complexed with mupirocin | Descriptor: | Isoleucyl-tRNA synthetase, MUPIROCIN, ZINC ION | Authors: | Nakama, T, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-09-17 | Release date: | 2001-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase. J.Biol.Chem., 276, 2001
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3UG9
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![BU of 3ug9 by Molmil](/molmil-images/mine/3ug9) | Crystal Structure of the Closed State of Channelrhodopsin | Descriptor: | Archaeal-type opsin 1, Archaeal-type opsin 2, OLEIC ACID, ... | Authors: | Kato, H.E, Ishitani, R, Nureki, O. | Deposit date: | 2011-11-02 | Release date: | 2012-01-25 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the channelrhodopsin light-gated cation channel Nature, 482, 2012
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5ZSU
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![BU of 5zsu by Molmil](/molmil-images/mine/5zsu) | Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms | Descriptor: | Volume-regulated anion channel subunit LRRC8A | Authors: | Kasuya, G, Nakane, T, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | Deposit date: | 2018-04-29 | Release date: | 2018-08-15 | Last modified: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Cryo-EM structures of the human volume-regulated anion channel LRRC8. Nat. Struct. Mol. Biol., 25, 2018
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3S7T
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![BU of 3s7t by Molmil](/molmil-images/mine/3s7t) | |
7YU5
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![BU of 7yu5 by Molmil](/molmil-images/mine/7yu5) | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state1 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU3
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![BU of 7yu3 by Molmil](/molmil-images/mine/7yu3) | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU8
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![BU of 7yu8 by Molmil](/molmil-images/mine/7yu8) | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state4 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU6
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![BU of 7yu6 by Molmil](/molmil-images/mine/7yu6) | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state2 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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7YU7
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![BU of 7yu7 by Molmil](/molmil-images/mine/7yu7) | Human Lysophosphatidic Acid Receptor 1-Gi complex bound to ONO-0740556, state3 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Akasaka, H, Shihoya, W, Nureki, O. | Deposit date: | 2022-08-16 | Release date: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the active G i -coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist. Nat Commun, 13, 2022
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3UG0
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![BU of 3ug0 by Molmil](/molmil-images/mine/3ug0) | Crystal structure of a Trp-less green fluorescent protein translated by the simplified genetic code | Descriptor: | Green fluorescent protein | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | Deposit date: | 2011-11-02 | Release date: | 2012-10-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.093 Å) | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Res., 40, 2012
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1KN0
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![BU of 1kn0 by Molmil](/molmil-images/mine/1kn0) | Crystal Structure of the human Rad52 protein | Descriptor: | Rad52 | Authors: | Kagawa, W, Kurumizaka, H, Ishitani, R, Fukai, S, Nureki, O, Shibata, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-12-18 | Release date: | 2002-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol.Cell, 10, 2002
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3UFZ
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![BU of 3ufz by Molmil](/molmil-images/mine/3ufz) | Crystal structure of a Trp-less green fluorescent protein translated by the universal genetic code | Descriptor: | Green fluorescent protein | Authors: | Kawahara-Kobayashi, A, Araiso, Y, Matsuda, T, Yokoyama, S, Kigawa, T, Nureki, O, Kiga, D. | Deposit date: | 2011-11-02 | Release date: | 2012-10-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Simplification of the genetic code: restricted diversity of genetically encoded amino acids. Nucleic Acids Res., 40, 2012
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8GW8
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![BU of 8gw8 by Molmil](/molmil-images/mine/8gw8) | the human PTH1 receptor bound to an intracellular biased agonist | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Kobayashi, K, Kusakizako, T, Okamoto, H.H, Nureki, O. | Deposit date: | 2022-09-16 | Release date: | 2023-06-14 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Class B1 GPCR activation by an intracellular agonist. Nature, 618, 2023
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4PDN
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![BU of 4pdn by Molmil](/molmil-images/mine/4pdn) | Crystal structure of E. coli YfcM | Descriptor: | MAGNESIUM ION, Uncharacterized protein | Authors: | Kobayashi, K, Ishii, R, Ishitani, R, Nureki, O. | Deposit date: | 2014-04-19 | Release date: | 2015-03-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.448 Å) | Cite: | The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation. Nucleic Acids Res., 42, 2014
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7BTW
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![BU of 7btw by Molmil](/molmil-images/mine/7btw) | The mitochondrial SAM complex from S.cere | Descriptor: | Mitochondrial outer membrane beta-barrel protein, SAM37 isoform 1, Sorting assembly machinery 35 kDa subunit | Authors: | Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. | Deposit date: | 2020-04-03 | Release date: | 2021-01-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
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7BTX
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![BU of 7btx by Molmil](/molmil-images/mine/7btx) | The mitochondrial SAM-Mdm10 supercomplex in GDN micelle from S.cere | Descriptor: | MDM10 isoform 1, Mitochondrial outer membrane beta-barrel protein, Sorting assembly machinery 35 kDa subunit, ... | Authors: | Takeda, H, Tsutsumi, A, Nishizawa, T, Nureki, O, Kikkawa, M, Endo, T. | Deposit date: | 2020-04-03 | Release date: | 2021-01-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mitochondrial sorting and assembly machinery operates by beta-barrel switching. Nature, 590, 2021
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