5ZSU

Structure of the human homo-hexameric LRRC8A channel at 4.25 Angstroms

Summary for 5ZSU

• Entry DOI: 10.2210/pdb5zsu/pdb
• EMDB information: 6952
• Descriptor: Volume-regulated anion channel subunit LRRC8A (1 entity in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 571629.10

Authors

Kasuya, G.,Nakane, T.,Yokoyama, T.,Shirouzu, M.,Ishitani, R.,Nureki, O. (deposition date: 2018-04-29, release date: 2018-08-15, Last modification date: 2018-09-26)

• Primary citation: Kasuya, G.,Nakane, T.,Yokoyama, T.,Jia, Y.,Inoue, M.,Watanabe, K.,Nakamura, R.,Nishizawa, T.,Kusakizako, T.,Tsutsumi, A.,Yanagisawa, H.,Dohmae, N.,Hattori, M.,Ichijo, H.,Yan, Z.,Kikkawa, M.,Shirouzu, M.,Ishitani, R.,Nureki, O.; Cryo-EM structures of the human volume-regulated anion channel LRRC8.; Nat. Struct. Mol. Biol., 25:797-804, 2018; PubMed: 30127360; DOI: 10.1038/s41594-018-0109-6

Experimental method

ELECTRON MICROSCOPY (4.25 Å)