PDB Search results for query - 일본 단백질구조 데이터 뱅크

PDB: 66 results

AIIGLMV segment from Alzheimer's Amyloid-Beta displayed on 54-membered macrocycle scaffold
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide (ORN)AIIGLMV(ORN)KF(HAO)(4BF)K
Authors:	Zhao, M, Liu, C, Cheng, P.N, Eisenberg, D, Nowick, J.S.
Deposit date:	2011-07-26
Release date:	2012-10-31
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Amyloid beta-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity. Nat Chem, 4, 2012

5HOX

X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV).
Descriptor:	Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:	Kreutzer, A.G, Nowick, J.S, Spencer, R.K.
Deposit date:	2016-01-19
Release date:	2016-03-23
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016

5HOY

X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (LVFFAEDCGSNKCAII(SAR)LMV).
Descriptor:	Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:	Kreutzer, A.G, Spencer, R.K, Nowick, J.S.
Deposit date:	2016-01-19
Release date:	2016-03-23
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.295 Å)
Cite:	X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016

5HOW

X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)V
Descriptor:	Amyloid beta A4 protein
Authors:	Kreutzer, A.G, Nowick, J.S, Spencer, R.K.
Deposit date:	2016-01-19
Release date:	2016-03-23
Last modified:	2019-12-25
Method:	X-RAY DIFFRACTION (2.295 Å)
Cite:	X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin. J.Am.Chem.Soc., 138, 2016

5HPP

Crystal structure of a macrocyclic beta-sheet peptide derived from transthyretin (106-121) - (ORN)TIA(MAA)LLS(ORN)S(PHI)STTAV
Descriptor:	CHLORIDE ION, ORN-THR-ILE-ALA-MAA-LEU-LEU-SER-ORN-SER-PHI-SER-THR-THR-ALA-VAL
Authors:	Yoo, S, Kreutzer, A.G, Nowick, J.S.
Deposit date:	2016-01-20
Release date:	2016-08-10
Last modified:	2019-12-25
Method:	X-RAY DIFFRACTION (2.082 Å)
Cite:	Square channels formed by a peptide derived from transthyretin. Chem Sci, 7, 2016

5F1W

Crystal structure of the enantiomer of a macrocyclic peptide containing fragments from alpha synuclein 36-55
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, Macrocyclic peptide, SULFATE ION
Authors:	Salveson, P.J, Spencer, R.K, Nowick, J.S.
Deposit date:	2015-11-30
Release date:	2016-03-16
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.161 Å)
Cite:	X-ray Crystallographic Structure of Oligomers Formed by a Toxic beta-Hairpin Derived from alpha-Synuclein: Trimers and Higher-Order Oligomers. J.Am.Chem.Soc., 138, 2016

5F1T

Crystal structure of a macrocyclic peptide containing fragments from alpha-synuclein 36-55.
Descriptor:	(4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
Authors:	Salveson, P.J, Spencer, R.K, Nowick, J.S.
Deposit date:	2015-11-30
Release date:	2016-03-16
Last modified:	2016-04-27
Method:	X-RAY DIFFRACTION (1.971 Å)
Cite:	X-ray Crystallographic Structure of Oligomers Formed by a Toxic beta-Hairpin Derived from alpha-Synuclein: Trimers and Higher-Order Oligomers. J.Am.Chem.Soc., 138, 2016

7JXO

Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutation
Descriptor:	Amyloid-beta 17-36 peptide
Authors:	Kreutzer, A.G, Haerianardakani, S, Nowick, J.S.
Deposit date:	2020-08-27
Release date:	2020-12-09
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.81 Å)
Cite:	Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta. J.Am.Chem.Soc., 142, 2020

7JQU

Abeta 16-36 beta-hairpin mimic with E22G Arctic mutation
Descriptor:	Abeta 16-36 beta-hairpin mimic VAL-ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLN-ORN-ALA-ILE-ILE-GLY-LEU-MET
Authors:	Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
Deposit date:	2020-08-11
Release date:	2021-09-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.611 Å)
Cite:	Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 . Biochemistry, 61, 2022

7JQS

Abeta 16-36 beta-hairpin mimic with E22delta Osaka mutation
Descriptor:	Abeta 16-36 beta-hairpin mimic VAL-ORN-LYS-LEU-VAL-MEA-PHE-ALA-ASP-ORN-ALA-ILE-ILE-GLY-LEU-MET
Authors:	Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
Deposit date:	2020-08-11
Release date:	2021-09-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.127 Å)
Cite:	Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 . Biochemistry, 61, 2022

7JQR

Abeta 16-36 beta-hairpin mimic with E22G Arctic mutation
Descriptor:	Abeta 16-36 beta-hairpin mimic VAL-ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLY-ORN-ALA-ILE-ILE-GLY-LEU-MET, IODIDE ION
Authors:	Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
Deposit date:	2020-08-11
Release date:	2021-09-08
Last modified:	2022-03-30
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 . Biochemistry, 61, 2022

7JQT

Abeta 16-36 beta-hairpin mimic with E22K Italian mutation
Descriptor:	Abeta 16-36 beta-hairpin mimic VAL-ORT-LYS-LEU-VAL-MEA-PHE-ALA-LYS-ORT-ALA-ILE-ILE-GLY-LEU-MET
Authors:	Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
Deposit date:	2020-08-11
Release date:	2021-09-08
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Effects of Familial Alzheimer's Disease Mutations on the Assembly of a beta-Hairpin Peptide Derived from A beta 16-36 . Biochemistry, 61, 2022

7JXN

Beta hairpin derived from Abeta17-36 with an F20Cha mutation
Descriptor:	Amyloid-beta 17-36 peptide, CHLORIDE ION, SODIUM ION
Authors:	Kreutzer, A.G, Haerianardakani, S, Nowick, J.S.
Deposit date:	2020-08-27
Release date:	2020-12-09
Last modified:	2020-12-23
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Phenylalanine Mutation to Cyclohexylalanine Facilitates Triangular Trimer Formation by beta-Hairpins Derived from A beta. J.Am.Chem.Soc., 142, 2020

7JRH

X-ray crystal structure of a cyclic peptide containing medin(19-25) and medin(31-37)
Descriptor:	CALCIUM ION, Cyclic peptide ASP-GLN-TRP-MLE-GLN-VAL-ASP-ORD-GLU-VAL-THR-GLY-ILE-ILE-THR-ORD
Authors:	Wierzbicki, M, Howitz, W.J, Nowick, J.S.
Deposit date:	2020-08-12
Release date:	2020-09-09
Last modified:	2020-09-30
Method:	X-RAY DIFFRACTION (1.32 Å)
Cite:	Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin 19-36 . J.Am.Chem.Soc., 142, 2020

5UHR

Crystal structure of (Cit)LANFLV heptapeptide segment from islet amyloid polypeptide (IAPP) incorporated into a macrocyclic beta-sheet template
Descriptor:	CHLORIDE ION, ORN-CIR-LEU-ALA-ASN-PHE-LEU-VAL-ORN-ILE-LYS-HAO-LYS-A8E
Authors:	Wang, Y, Kreutzer, A.G, Nowick, J.S.
Deposit date:	2017-01-11
Release date:	2017-07-12
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.798 Å)
Cite:	A Tetramer Derived from Islet Amyloid Polypeptide. J. Org. Chem., 82, 2017

6CG3

Macrocyclic peptide derived from Abeta(17-36) - (ORN)LV(PHI)FAED(ORN)AII(2-nitrobenzylglycine)L(ORN)V
Descriptor:	ORN-LEU-VAL-PHI-PHE-ALA-GLU-ASP-ORN-ALA-ILE-ILE-EZY-LEU-ORN-VAL
Authors:	Salveson, P.J, Nowick, J.S.
Deposit date:	2018-02-19
Release date:	2018-05-16
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.03 Å)
Cite:	Controlling the Oligomerization State of A beta-Derived Peptides with Light. J. Am. Chem. Soc., 140, 2018

6CG5

Covalently crosslinked trimer of a macrocyclic peptide derived from Abeta (17-36) - (ORN)LCVFFCED(ORN)AII(2-nitrobenzylglycine)L(ORN)V
Descriptor:	ORN-CYS-VAL-PHE-PHE-CYS-GLU-ASP-ORN-ALA-ILE-ILE-EZY-LEU-ORN-VAL
Authors:	Salveson, P.J, Nowick, J.S.
Deposit date:	2018-02-19
Release date:	2018-05-16
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Controlling the Oligomerization State of A beta-Derived Peptides with Light. J. Am. Chem. Soc., 140, 2018

5V65

Crystal structure of macrocycles containing Abeta 17-23 (LV(PHI)FAED) and Abeta 30-36 (AII(SAR)L(ORN)V)
Descriptor:	ORN-LEU-VAL-PHI-PHE-ALA-GLU-ASP-ORN-ALA-ILE-ILE-SAR-LEU-MET-VAL
Authors:	Kreutzer, A.G, Salveson, P.J, Nowick, J.S.
Deposit date:	2017-03-15
Release date:	2017-06-28
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.52 Å)
Cite:	X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from A beta 16-36. Org. Lett., 19, 2017

5V64

Crystal structure of macrocycles containing Abeta 15-21 (QKLV(PHI)FA) and Abeta 30-36 (AII(SAR)L(ORN)V)
Descriptor:	CITRATE ANION, ORN-GLN-LYS-LEU-VAL-PHI-PHE-ALA-ORN-ALA-ILE-ILE-SAR-LEU-MET-VAL, SODIUM ION
Authors:	Salveson, P.J, Spencer, R.K, Nowick, J.S.
Deposit date:	2017-03-15
Release date:	2017-06-28
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.023 Å)
Cite:	X-ray Crystallographic Structure of a Compact Dodecamer from a Peptide Derived from A beta 16-36. Org. Lett., 19, 2017

6DR5

X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36 containing the I31Chg point mutation
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, ORT-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORT-ALA-CHG-ILE-GLY-LEU-ORA-VAL
Authors:	Salveson, P.J, Nowick, J.S.
Deposit date:	2018-06-11
Release date:	2018-10-17
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.079 Å)
Cite:	Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from A beta. J. Am. Chem. Soc., 140, 2018

5VF1

X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic Beta-Sheet Containing ABeta16-22
Descriptor:	ORN-LYS-LEU-VAL-PHI-PHE-ALA-GLU-ORN-GLU-ALA-PHE-MEA-VAL-LEU-LYS
Authors:	Chen, K.H, Corro, K.A, Le, S.P, Nowick, J.S.
Deposit date:	2017-04-06
Release date:	2017-06-21
Last modified:	2019-11-27
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	X-ray Crystallographic Structure of a Giant Double-Walled Peptide Nanotube Formed by a Macrocyclic beta-Sheet Containing A beta 16-22. J. Am. Chem. Soc., 139, 2017

6DR4

X-ray crystallographic structure of a covalent trimer derived from A-beta 17_36 containing the I31V point mutation
Descriptor:	HEXANE-1,6-DIOL, ORN-CYS-VAL-PHE-MEA-CYS-GLU-ASP-ORN-ALA-VAL-ILE-GLY-LEU-ORN-VAL
Authors:	Salveson, P.J, Nowick, J.S.
Deposit date:	2018-06-11
Release date:	2018-10-17
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.105 Å)
Cite:	Repurposing Triphenylmethane Dyes to Bind to Trimers Derived from A beta. J. Am. Chem. Soc., 140, 2018

5W4H

X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Synchrotron data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Descriptor:	A-beta 17_36 peptide: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL
Authors:	Kreutzer, A.G, Spencer, R.K, Nowick, J.S.
Deposit date:	2017-06-11
Release date:	2017-11-22
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.718 Å)
Cite:	A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56, 2017

5W4I

X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Rigaku data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Descriptor:	A-beta 17_36: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL, CHLORIDE ION, IODIDE ION
Authors:	Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
Deposit date:	2017-06-11
Release date:	2017-11-22
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.026 Å)
Cite:	A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56, 2017

5W4J

X-ray crystallographic structure of a beta-hairpin peptide mimic. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Descriptor:	A-beta 17_36 peptide: ORN-LYS-VAL-PHE-MEA-ALA-ALA-ASP-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL
Authors:	Kreutzer, A.G, Nowick, J.S.
Deposit date:	2017-06-11
Release date:	2017-11-22
Last modified:	2020-01-01
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	A Hexamer of a Peptide Derived from A beta 16-36. Biochemistry, 56, 2017

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Total results:	66
Displayed results:	25
Sorted by:	Hit score (from highest)
Deposition authors:	"Nowick, J.S"