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PDB: 98 results

4Z09
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BU of 4z09 by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Thr2040Ala] peptide
Descriptor: Apical membrane antigen 1, GLYCEROL, Rhoptry neck protein 2
Authors:Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
Deposit date:2015-03-26
Release date:2016-08-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
6DN8
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SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor
Descriptor: (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ...
Authors:Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
Deposit date:2018-06-06
Release date:2019-04-17
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN5
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SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor
Descriptor: SPRY domain-containing SOCS box protein 2, SULFATE ION, WDINNN(BAL) cyclic peptide inhibitor
Authors:Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
Deposit date:2018-06-06
Release date:2019-04-17
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
1AHL
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BU of 1ahl by Molmil
ANTHOPLEURIN-A,NMR, 20 STRUCTURES
Descriptor: ANTHOPLEURIN-A
Authors:Pallaghy, P.K, Scanlon, M.J, Monks, S.A, Norton, R.S.
Deposit date:1994-10-28
Release date:1995-11-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure in solution of the polypeptide cardiac stimulant anthopleurin-A.
Biochemistry, 34, 1995
1OWT
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BU of 1owt by Molmil
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain
Descriptor: Amyloid beta A4 protein
Authors:Barnham, K.J, McKinstry, W.J, Multhaup, G, Galatis, D, Morton, C.J, Curtain, C.C, Williamson, N.A, White, A.R, Hinds, M.G, Norton, R.S, Beyreuther, K, Masters, C.L, Parker, M.W, Cappai, R.
Deposit date:2003-03-30
Release date:2003-05-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain. A REGULATOR OF NEURONAL COPPER HOMEOSTASIS.
J.Biol.Chem., 278, 2003
1ANS
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BU of 1ans by Molmil
THREE-DIMENSIONAL STRUCTURE IN SOLUTION OF NEUROTOXIN III FROM THE SEA ANEMONE ANEMONIA SULCATA
Descriptor: NEUROTOXIN III
Authors:Manoleras, N, Norton, R.S.
Deposit date:1994-06-09
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure in solution of neurotoxin III from the sea anemone Anemonia sulcata.
Biochemistry, 33, 1994
1APF
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BU of 1apf by Molmil
ANTHOPLEURIN-B, NMR, 20 STRUCTURES
Descriptor: ANTHOPLEURIN-B
Authors:Monks, S.A, Pallaghy, P.K, Scanlon, M.J, Norton, R.S.
Deposit date:1995-05-30
Release date:1996-07-11
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the cardiostimulant polypeptide anthopleurin-B and comparison with anthopleurin-A.
Structure, 3, 1995
1VIB
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BU of 1vib by Molmil
NMR SOLUTION STRUCTURE OF THE NEUROTOXIN B-IV, 20 STRUCTURES
Descriptor: NEUROTOXIN B-IV
Authors:Barnham, K.J, Dyke, T.R, Kem, W.R, Norton, R.S.
Deposit date:1996-11-25
Release date:1997-05-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding.
J.Mol.Biol., 268, 1997
2SH1
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BU of 2sh1 by Molmil
SOLUTION STRUCTURE OF NEUROTOXIN I FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS. A NUCLEAR MAGNETIC RESONANCE, DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS STUDY
Descriptor: NEUROTOXIN I
Authors:Fogh, R.H, Norton, R.S.
Deposit date:1990-05-03
Release date:1991-10-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.
J.Biol.Chem., 265, 1990
5WCV
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BU of 5wcv by Molmil
AsK132958: A minimal homologue of ShK identified in the transcriptome of Anemonia sulcata
Descriptor: ShK homolog AsK132958
Authors:Krishnarjuna, B, MacRaild, C.A, Norton, R.S.
Deposit date:2017-07-02
Release date:2017-10-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.
Peptides, 99, 2018
8SEM
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BU of 8sem by Molmil
Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni
Descriptor: TRPV1 inhibitory peptide Tst2
Authors:Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
Deposit date:2023-04-10
Release date:2023-09-27
Method:SOLUTION NMR
Cite:Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
8SED
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BU of 8sed by Molmil
Structure of a new ShKT peptide from the sea anemone Telmatactis stephensoni: ShKT-Ts1
Descriptor: ShKT peptide ShKT-Ts1
Authors:Sanches, K, Siedoks, A.A, Wai, D.C.C, Norton, R.S.
Deposit date:2023-04-09
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Structure-function relationships in ShKT domain peptides: ShKT-Ts1 from the sea anemone Telmatactis stephensoni.
Proteins, 92, 2024
5JYQ
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BU of 5jyq by Molmil
Structure of Conus Geographus insulin G1
Descriptor: Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
8F04
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BU of 8f04 by Molmil
Structure of elevenin-Vc1 from venom of the Australian cone snail Conus victoriae
Descriptor: Elevenin-Vc1
Authors:Krishnarjuna, B, Sunanda, P, Norton, R.S.
Deposit date:2022-11-01
Release date:2023-09-13
Method:SOLUTION NMR
Cite:Characterisation of Elevenin-Vc1 from the Venom of Conus victoriae : A Structural Analogue of alpha-Conotoxins.
Mar Drugs, 21, 2023
7KNN
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BU of 7knn by Molmil
Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
Descriptor: Alpha-conotoxin Vc1a
Authors:MacRaild, C.A, Robinson, S.D, Chhabra, S, Norton, R.S.
Deposit date:2020-11-05
Release date:2021-09-15
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
J.Med.Chem., 64, 2021
1A3P
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BU of 1a3p by Molmil
ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor: EPIDERMAL GROWTH FACTOR
Authors:Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R.
Deposit date:1998-01-22
Release date:1998-07-29
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
1YXE
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BU of 1yxe by Molmil
Structure and inter-domain interactions of domain II from the blood stage malarial protein, apical membrane antigen 1
Descriptor: apical membrane antigen 1
Authors:Feng, Z.P, Keizer, D.W, Stevenson, R.A, Yao, S, Babon, J.J, Murphy, V.J, Anders, R.F, Norton, R.S.
Deposit date:2005-02-21
Release date:2005-07-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Inter-domain Interactions of Domain II from the Blood-stage Malarial Protein, Apical Membrane Antigen 1.
J.Mol.Biol., 350, 2005
6OQP
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BU of 6oqp by Molmil
U-AITx-Ate1
Descriptor: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE
Authors:Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
Deposit date:2019-04-28
Release date:2019-07-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
5TBD
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BU of 5tbd by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222
Descriptor: Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2
Authors:Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S.
Deposit date:2016-09-12
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2.
J. Mol. Biol., 429, 2017
3EK9
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BU of 3ek9 by Molmil
SPRY Domain-containing SOCS Box Protein 2: Crystal Structure and Residues Critical for Protein Binding
Descriptor: GLYCEROL, SPRY domain-containing SOCS box protein 2
Authors:Kuang, Z, Yao, S, Xu, Y, Garrett, T.J.P, Norton, R.S.
Deposit date:2008-09-19
Release date:2009-02-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding.
J.Mol.Biol., 386, 2009
1A7M
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BU of 1a7m by Molmil
LEUKAEMIA INHIBITORY FACTOR CHIMERA (MH35-LIF), NMR, 20 STRUCTURES
Descriptor: LEUKEMIA INHIBITORY FACTOR
Authors:Hinds, M.G, Maurer, T, Zhang, J.-G, Nicola, N.A, Norton, R.S.
Deposit date:1998-03-16
Release date:1999-04-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of leukemia inhibitory factor.
J.Biol.Chem., 273, 1998
1KD6
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BU of 1kd6 by Molmil
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II
Descriptor: EQUINATOXIN II
Authors:Hinds, M.G, Zhang, W, Anderluh, G, Hansen, P.E, Norton, R.S.
Deposit date:2001-11-12
Release date:2002-02-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
J.Mol.Biol., 315, 2002
1IGL
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BU of 1igl by Molmil
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS
Descriptor: INSULIN-LIKE GROWTH FACTOR II
Authors:Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S.
Deposit date:1994-12-29
Release date:1995-02-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
J.Mol.Biol., 248, 1995
6MJV
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BU of 6mjv by Molmil
A consensus human beta defensin
Descriptor: Human beta-defensin
Authors:Amero, C, Villegas-Moreno, J, Rodriguez, A, Norton, R.S, Corzo, G.
Deposit date:2018-09-22
Release date:2019-08-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Antimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10.
Proteins, 88, 2020
4Z0F
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BU of 4z0f by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038(6CW)] peptide
Descriptor: Apical membrane antigen 1, Rhoptry neck protein 2
Authors:Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
Deposit date:2015-03-26
Release date:2016-08-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016

 

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