4Z0F
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038(6CW)] peptide
Summary for 4Z0F
Entry DOI | 10.2210/pdb4z0f/pdb |
Related | 4Z09 4Z0D 4Z0E |
Descriptor | Apical membrane antigen 1, Rhoptry neck protein 2 (3 entities in total) |
Functional Keywords | cell invasion, inhibitor, ama1, malaria |
Biological source | Plasmodium falciparum Vietnam Oak-Knoll (FVO) More |
Total number of polymer chains | 2 |
Total formula weight | 39920.08 |
Authors | Wang, G.,McGowan, S.,Norton, R.S.,Scanlon, M.J. (deposition date: 2015-03-26, release date: 2016-08-03, Last modification date: 2023-09-27) |
Primary citation | Wang, G.,Drinkwater, N.,Drew, D.R.,MacRaild, C.A.,Chalmers, D.K.,Mohanty, B.,Lim, S.S.,Anders, R.F.,Beeson, J.G.,Thompson, P.E.,McGowan, S.,Simpson, J.S.,Norton, R.S.,Scanlon, M.J. Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction. J.Mol.Biol., 428:3986-3998, 2016 Cited by PubMed: 27422009DOI: 10.1016/j.jmb.2016.07.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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