4KQO
 
 | | Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin | | 分子名称: | CHLORIDE ION, GLYCEROL, IMIDAZOLE, ... | | 著者 | Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. | | 登録日 | 2013-05-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
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4KQR
 | | CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid | | 分子名称: | (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | | 著者 | Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. | | 登録日 | 2013-05-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
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3DIF
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4I2X
 | | Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FabOX117 heavy chain, ... | | 著者 | Nettleship, J.E, Ren, J, Stuart, D.I, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2012-11-23 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structure of signal regulatory protein gamma (SIRP gamma) in complex with an antibody Fab fragment.
Bmc Struct.Biol., 13, 2013
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4KQQ
 | | CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid | | 分子名称: | (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | | 著者 | Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J. | | 登録日 | 2013-05-15 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
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4UXJ
 | | Leishmania major Thymidine Kinase in complex with dTTP | | 分子名称: | MAGNESIUM ION, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2014-08-22 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major.
Plos Negl Trop Dis, 9, 2015
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4UXH
 | | Leishmania major Thymidine Kinase in complex with AP5dT | | 分子名称: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, THYMIDINE KINASE, ZINC ION | | 著者 | Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2014-08-22 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major.
Plos Negl Trop Dis, 9, 2015
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4UXI
 | | Leishmania major Thymidine Kinase in complex with thymidine | | 分子名称: | PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ... | | 著者 | Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2014-08-22 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major.
Plos Negl Trop Dis, 9, 2015
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7OG0
 | | Nontypeable Haemophillus influenzae SapA in open and closed conformations, in complex with double stranded RNA | | 分子名称: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ... | | 著者 | Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A. | | 登録日 | 2021-05-05 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
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7OFZ
 | | Nontypeable Haemophillus influenzae SapA in complex with double stranded RNA | | 分子名称: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ... | | 著者 | Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A. | | 登録日 | 2021-05-05 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
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7OFW
 | | Nontypeable Haemophillus influenzae SapA in complex with heme | | 分子名称: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ... | | 著者 | Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A. | | 登録日 | 2021-05-05 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
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6QNA
 | | Structure of bovine anti-RSV hybrid Fab B13HC-B4LC | | 分子名称: | B13 Heavy chain, B4 light chain, GLYCEROL | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN9
 | | Structure of bovine anti-RSV Fab B4 | | 分子名称: | GLYCEROL, Heavy chain, SULFATE ION, ... | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN7
 | | Structure of bovine anti-RSV hybrid Fab B4HC-B13LC | | 分子名称: | Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13 | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN8
 | | Structure of bovine anti-RSV Fab B13 | | 分子名称: | CHLORIDE ION, Heavy chain of bovine anti-RSV B13 Fab, Light chain of bovine anti-RSV Fab B13 | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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2A0J
 | | Crystal Structure of Nitrogen Regulatory Protein IIA-Ntr from Neisseria meningitidis | | 分子名称: | PTS system, nitrogen regulatory IIA protein | | 著者 | Ren, J, Sainsbury, S, Berrow, N.S, Alderton, D, Nettleship, J.E, Stammers, D.K, Saunders, N.J, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2005-06-16 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of nitrogen regulatory protein IIANtr from Neisseria meningitidis
Bmc Struct.Biol., 5, 2005
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3KXA
 | | Crystal Structure of NGO0477 from Neisseria gonorrhoeae | | 分子名称: | ASPARAGINE, CHLORIDE ION, Putative uncharacterized protein, ... | | 著者 | Ren, J, Sainsbury, S, Nettleship, J.E, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2009-12-02 | | 公開日 | 2010-01-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The crystal structure of NGO0477 from Neisseria gonorrhoeae reveals a novel protein fold incorporating a helix-turn-helix motif.
Proteins, 78, 2010
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5ML9
 | | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer F4, a specific binding protein which blocks IgG binding to the receptor. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer F4 with specificity for Fc gamma receptor IIIa, CHLORIDE ION, ... | | 著者 | Robinson, J.I, Tomlinson, D.C, Baxter, E.W, Owen, R.L, Thomsen, M, Win, S.J, Nettleship, J.E, Tiede, C, Foster, R.J, Waterhouse, M.P, Harris, S.A, Owens, R.J, Fishwick, C.W.G, Goldman, A, McPherson, M.J, Morgan, A.W. | | 登録日 | 2016-12-06 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5MN2
 | | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding protein which blocks IgG binding to the receptor. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer G3, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Robinson, J.I, Owen, R.L, Tomlinson, D.C, Baxter, E.W, Nettleship, J.E, Waterhouse, M.P, Harris, S.A, Owens, R.J, McPherson, M.J, Morgan, A.W, Tiede, C, Goldman, A, Thomsen, M. | | 登録日 | 2016-12-12 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3DGG
 | | Crystal structure of FabOX108 | | 分子名称: | FabOX108 Heavy Chain Fragment, FabOX108 Light Chain Fragment, MAGNESIUM ION | | 著者 | Ren, J, Nettleship, J.E, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2008-06-13 | | 公開日 | 2008-08-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cells.
Protein Expr.Purif., 62, 2008
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4N6U
 | | Adhiron: a stable and versatile peptide display scaffold - truncated adhiron | | 分子名称: | Adhiron | | 著者 | Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J. | | 登録日 | 2013-10-14 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
Protein Eng.Des.Sel., 27, 2014
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4YU8
 | | Crystal structure of Neuroblastoma suppressor of tumorigenicity 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Neuroblastoma suppressor of tumorigenicity 1 | | 著者 | Ren, J, Nettleship, J.E, Stammers, D.K, Owens, R.J, Oxford Protein Production Facility (OPPF) | | 登録日 | 2015-03-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Neuroblastoma suppressor of tumorigenicity 1
To Be Published
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4N6T
 | | Adhiron: a stable and versatile peptide display scaffold - full length adhiron | | 分子名称: | Adhiron | | 著者 | Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J. | | 登録日 | 2013-10-14 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
Protein Eng.Des.Sel., 27, 2014
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5IOM
 | | Crystal Structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni is space group P6322 | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | | 登録日 | 2016-03-08 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.
Mol.Biochem.Parasitol., 2019
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5IOL
 | | Crystal structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | | 登録日 | 2016-03-08 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.741 Å) | | 主引用文献 | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.
Mol.Biochem.Parasitol., 2019
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