1RAS
 
 | | CRYSTAL STRUCTURE OF A FLUORESCENT DERIVATIVE OF RNASE A | | 分子名称: | 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE, RIBONUCLEASE A | | 著者 | Baudet-Nessler, S, Jullien, M, Crosio, M.-P, Janin, J. | | 登録日 | 1993-03-02 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a fluorescent derivative of RNase A.
Biochemistry, 32, 1993
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1RAR
 | | CRYSTAL STRUCTURE OF A FLUORESCENT DERIVATIVE OF RNASE A | | 分子名称: | 5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE, CHLORIDE ION, RIBONUCLEASE A | | 著者 | Baudet-Nessler, S, Jullien, M, Crosio, M.-P, Janin, J. | | 登録日 | 1993-03-02 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a fluorescent derivative of RNase A.
Biochemistry, 32, 1993
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5JUB
 | | Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS. | | 分子名称: | ComS, Transcriptional regulator, pComX-for, ... | | 著者 | Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. | | 登録日 | 2016-05-10 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
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6B3J
 | | 3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex | | 分子名称: | Exendin-P5, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Liang, Y.L, Khoshouei, M, Glukhova, A, Furness, S.G.B, Koole, C, Zhao, P, Clydesdale, L, Thal, D.M, Radjainia, M, Danev, R, Baumeister, W, Wang, M.W, Miller, L.J, Christopoulos, A, Sexton, P.M, Wootten, D. | | 登録日 | 2017-09-22 | | 公開日 | 2018-02-21 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature, 555, 2018
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2FEP
 | | Structure of truncated CcpA in complex with P-Ser-HPr and Sulfate ions | | 分子名称: | Catabolite control protein A, Phosphocarrier protein HPr, SULFATE ION | | 著者 | Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Meyer, P, Deutscher, J, Galinier, A, Nessler, S. | | 登録日 | 2005-12-16 | | 公開日 | 2006-06-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural analysis of B. subtilis CcpA effector binding site.
Proteins, 64, 2006
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5UZ7
 | | Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | | 分子名称: | Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Liang, Y.L, Khoshouei, M, Radjainia, M, Zhang, Y, Glukhova, A, Tarrasch, J, Thal, D.M, Furness, S.G.B, Christopoulos, G, Coudrat, T, Danev, R, Baumeister, W, Miller, L.J, Christopoulos, A, Kobilka, B.K, Wootten, D, Skiniotis, G, Sexton, P.M. | | 登録日 | 2017-02-24 | | 公開日 | 2017-05-03 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.
Nature, 546, 2017
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3LA6
 | | Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Tyrosine-protein kinase wzc | | 著者 | Gruszczyk, J, Nessler, S, Gueguen-Chaignon, V, Vigouroux, A, Bechet, E, Grangeasse, C. | | 登録日 | 2010-01-06 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export
Mol.Microbiol., 77, 2010
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2QMH
 | | structure of V267F mutant HprK/P | | 分子名称: | HPr kinase/phosphorylase | | 著者 | Chaptal, V, Vincent, F, Gueguen-Chaignon, V, Poncet, S, Deutscher, J, Nessler, S, Morera, S. | | 登録日 | 2007-07-16 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Analysis of the Bacterial HPr Kinase/Phosphorylase V267F Mutant Gives Insights into the Allosteric Regulation Mechanism of This Bifunctional Enzyme.
J.Biol.Chem., 282, 2007
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1JB1
 | | Lactobacillus casei HprK/P Bound to Phosphate | | 分子名称: | HPRK PROTEIN, PHOSPHATE ION | | 著者 | Fieulaine, S, Morera, S, Poncet, S, Monedero, V, Gueguen-Chaignon, V, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | 登録日 | 2001-06-01 | | 公開日 | 2001-08-08 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain.
EMBO J., 20, 2001
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2VED
 | | crystal structure of the chimerical mutant CapABK55M protein | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MEMBRANE PROTEIN CAPA1, ... | | 著者 | Olivares-Illana, V, Meyer, P, Gueguen-Chaignon, V, Soulat, D, Deustcher, J, Cozzone, A.J, Morera, S, Grangeasse, C, Nessler, S. | | 登録日 | 2007-10-19 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for the Regulation Mechanism of the Tyrosine Kinase Capb from Staphylococcus Aureus.
Plos Biol., 6, 2008
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9BKK
 | | Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex | | 分子名称: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Harikumar, K.G, Zhao, P, Cary, B.P, Xu, X, Desai, A.J, Mobbs, J.I, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J. | | 登録日 | 2024-04-29 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
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9BKJ
 | | Cholecystokinin 1 receptor (CCK1R) Y140A mutant, Gq chimera (mGsqi) complex | | 分子名称: | AMINO GROUP, Cholecystokinin receptor type A, Cholecystokinin-8, ... | | 著者 | Cary, B.P, Harikumar, K.G, Zhao, P, Desai, A.J, Mobbs, J.M, Toufaily, C, Furness, S.G.B, Christopoulos, A, Belousoff, M.J, Wootten, D, Sexton, P.M, Miller, L.J. | | 登録日 | 2024-04-29 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
To Be Published
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5Z1I
 | | Crystal structure of the protozoal cytoplasmic ribosomal decoding site in complex with 6'-fluoro sisomicin | | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(fluoromethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, RNA (5'-R(P*GP*CP*GP*UP*CP*GP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') | | 著者 | Kanazawa, H, Hanessian, S, Kondo, J. | | 登録日 | 2017-12-26 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | | 主引用文献 | Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside.
ChemMedChem, 13, 2018
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5Z1H
 | | Crystal structure of the bacterial ribosomal decoding site in complex with 6'-fluoro sisomicin | | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(fluoromethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') | | 著者 | Kanazawa, H, Hanessian, S, Kondo, J. | | 登録日 | 2017-12-26 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside.
ChemMedChem, 13, 2018
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1KKL
 | | L.casei HprK/P in complex with B.subtilis HPr | | 分子名称: | CALCIUM ION, HprK protein, PHOSPHOCARRIER PROTEIN HPR | | 著者 | Fieulaine, S, Morera, S, Poncet, S, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | 登録日 | 2001-12-10 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr.
Proc.Natl.Acad.Sci.USA, 99, 2002
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4JLV
 | | Crystal structure of the chimerical protein CapA1B1 in complex with ADP-Mg | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, C-terminal fragment of Membrane protein CapA1, Putative uncharacterized protein capB1, ... | | 著者 | Gruszczyk, J, Olivares-Illana, V, Nourikyan, J, Fleurie, A, Bechet, E, Aumont-Nicaise, M, Gueguen-Chaignon, V, Morera, S, Grangeasse, C, Nessler, S. | | 登録日 | 2013-03-13 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus
Plos One, 8, 2013
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1KO7
 | | X-ray structure of the HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution | | 分子名称: | Hpr kinase/phosphatase, PHOSPHATE ION | | 著者 | Marquez, J.A, Hasenbein, S, Koch, B, Fieulaine, S, Nessler, S, Hengstenberg, W, Scheffzek, K. | | 登録日 | 2001-12-20 | | 公開日 | 2002-04-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions.
Proc.Natl.Acad.Sci.USA, 99, 2002
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4JMP
 | | Crystal structure of the chimerical protein CapA2B2 | | 分子名称: | C-terminal fragment of CapA, Protein tyrosine kinase | | 著者 | Olivares-Illana, V, Morera, S, Grangeasse, C, Nessler, S. | | 登録日 | 2013-03-14 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Comparative analysis of the Tyr-kinases CapB1 and CapB2 fused to their cognate modulators CapA1 and CapA2 from Staphylococcus aureus
Plos One, 8, 2013
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2AK7
 | | structure of a dimeric P-Ser-Crh | | 分子名称: | HPr-like protein crh, SULFATE ION | | 著者 | Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Lariviere, L, Meyer, P, Galinier, A, Deutscher, J, Nessler, S, Morera, S. | | 登録日 | 2005-08-03 | | 公開日 | 2006-06-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis.
Proteins, 63, 2006
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1KKM
 | | L.casei HprK/P in complex with B.subtilis P-Ser-HPr | | 分子名称: | CALCIUM ION, HprK protein, PHOSPHATE ION, ... | | 著者 | Fieulaine, S, Morera, S, Poncet, S, Galinier, A, Janin, J, Deutscher, J, Nessler, S. | | 登録日 | 2001-12-10 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr.
Proc.Natl.Acad.Sci.USA, 99, 2002
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4PUF
 | | Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1 | | 分子名称: | E3 ubiquitin-protein ligase SlrP, Thioredoxin | | 著者 | Zouhir, S, Bernal-Bayard, J, Cordero-Alba, M, Cardenal-Munoz, E, Guimaraes, B, Lazar, N, Ramos-Morales, F, Nessler, S. | | 登録日 | 2014-03-13 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.296 Å) | | 主引用文献 | The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family.
Biochem.J., 464, 2014
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3WRU
 | | Crystal structure of the bacterial ribosomal decoding site in complex with synthetic aminoglycoside with F-HABA group | | 分子名称: | (2R,3R)-4-amino-N-[(1R,2S,3R,4R,5S)-5-amino-4-[(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)oxy]-3-{[3-O-(2,6-diamino-2,3,4,6-tetradeoxy-beta-L-threo-hexopyranosyl)-beta-D-ribofuranosyl]oxy}-2-hydroxycyclohexyl]-3-fluoro-2-hydroxybutanamide, POTASSIUM ION, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3') | | 著者 | Maianti, J.P, Kanazawa, H, Dozzo, P, Feeney, L.A, Armstrong, E.S, Kondo, J, Hanessian, S. | | 登録日 | 2014-02-27 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Toxicity Modulation, Resistance Enzyme Evasion, and A-Site X-ray Structure of Broad-Spectrum Antibacterial Neomycin Analogs
Acs Chem.Biol., 9, 2014
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4GPK
 | | Crystal structure of NprR in complex with its cognate peptide NprX | | 分子名称: | NprR, NprX peptide | | 著者 | Zouhir, S, Guimaraes, B, Perchat, S, Nicaise, M, Lereclus, D, Nessler, S. | | 登録日 | 2012-08-21 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Peptide-binding dependent conformational changes regulate the transcriptional activity of the quorum-sensor NprR.
Nucleic Acids Res., 41, 2013
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3U3W
 | | Crystal Structure of Bacillus thuringiensis PlcR in complex with the peptide PapR7 and DNA | | 分子名称: | 5'-D(P*AP*TP*AP*TP*GP*AP*AP*AP*TP*AP*TP*TP*GP*CP*AP*TP*AP*G)-3', 5'-D(P*CP*TP*AP*TP*GP*CP*AP*AP*TP*AP*TP*TP*TP*CP*AP*TP*AP*T)-3', C-terminus heptapeptide from PapR protein, ... | | 著者 | Grenha, R, Slamti, L, Bouillaut, L, Lereclus, D, Nessler, S. | | 登録日 | 2011-10-06 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2PWT
 | | Crystal structure of the bacterial ribosomal decoding site complexed with aminoglycoside containing the L-HABA group | | 分子名称: | 22-mer of the ribosomal decoding site, DOUBLY FUNCTIONALIZED PAROMOMYCIN PM-II-162 | | 著者 | Kondo, J, Pachamuthu, K, Francois, B, Szychowski, J, Hanessian, S, Westhof, E. | | 登録日 | 2007-05-13 | | 公開日 | 2007-09-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity
Chemmedchem, 2, 2007
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