6M04
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![BU of 6m04 by Molmil](/molmil-images/mine/6m04) | Structure of the human homo-hexameric LRRC8D channel at 4.36 Angstroms | Descriptor: | Volume-regulated anion channel subunit LRRC8D | Authors: | Nakamura, R, Kasuya, G, Yokoyama, T, Shirouzu, M, Ishitani, R, Nureki, O. | Deposit date: | 2020-02-20 | Release date: | 2020-06-17 | Method: | ELECTRON MICROSCOPY (4.36 Å) | Cite: | Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation. Commun Biol, 3, 2020
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7CET
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![BU of 7cet by Molmil](/molmil-images/mine/7cet) | Crystal structure of D-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEU
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![BU of 7ceu by Molmil](/molmil-images/mine/7ceu) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEQ
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![BU of 7ceq by Molmil](/molmil-images/mine/7ceq) | |
7CER
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![BU of 7cer by Molmil](/molmil-images/mine/7cer) | Crystal structure of D-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis | Descriptor: | Cysteine desulfurase SufS, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEP
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![BU of 7cep by Molmil](/molmil-images/mine/7cep) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS from Bacillus subtilis | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Yasuhiro, T, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7CEO
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![BU of 7ceo by Molmil](/molmil-images/mine/7ceo) | |
7CES
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![BU of 7ces by Molmil](/molmil-images/mine/7ces) | Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS H121A from Bacillus subtilis | Descriptor: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2020-06-24 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022
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7XES
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![BU of 7xes by Molmil](/molmil-images/mine/7xes) | NifS with L-penicillamine | Descriptor: | (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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7XEN
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![BU of 7xen by Molmil](/molmil-images/mine/7xen) | SufS with L-penicillamine | Descriptor: | (2~{R})-3-methyl-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-butanoic acid, Cysteine desulfurase SufS | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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7XEK
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![BU of 7xek by Molmil](/molmil-images/mine/7xek) | SufS with D-cysteine for 6 h | Descriptor: | (2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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7XET
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![BU of 7xet by Molmil](/molmil-images/mine/7xet) | SufS with beta-cyano-L-alanine | Descriptor: | (2~{E})-3-cyano-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylimino]propanoic acid, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Inhibition mechanism of SufS by L-propargylglycine to be published
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7XEP
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![BU of 7xep by Molmil](/molmil-images/mine/7xep) | SufS with L-propargylglycine | Descriptor: | 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Inhibition mechanism of SufS by L-propargylglycine to be published
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7XEQ
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![BU of 7xeq by Molmil](/molmil-images/mine/7xeq) | NifS with D-cysteine | Descriptor: | (2~{S},4~{S})-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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7XEL
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![BU of 7xel by Molmil](/molmil-images/mine/7xel) | SufS soaked with D-penicillamine | Descriptor: | 1,2-ETHANEDIOL, Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, ... | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-03-31 | Release date: | 2023-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine to be published
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7YB3
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![BU of 7yb3 by Molmil](/molmil-images/mine/7yb3) | SufS with D-cysteine for 1 min | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL | Authors: | Nakamura, R, Fujishiro, T. | Deposit date: | 2022-06-28 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Snapshots of thiazolidine fomration of PLP-dependent enzyme SufS to be published
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5ZS9
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![BU of 5zs9 by Molmil](/molmil-images/mine/5zs9) | |
5ZSR
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![BU of 5zsr by Molmil](/molmil-images/mine/5zsr) | |
5ZST
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![BU of 5zst by Molmil](/molmil-images/mine/5zst) | |
5ZSQ
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5ZSK
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![BU of 5zsk by Molmil](/molmil-images/mine/5zsk) | |
5ZSP
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![BU of 5zsp by Molmil](/molmil-images/mine/5zsp) | NifS from Hydrogenimonas thermophila | Descriptor: | Cysteine desulfurase | Authors: | Nakamura, R, Fujishiro, T, Takahashi, Y. | Deposit date: | 2018-04-29 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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5ZSO
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![BU of 5zso by Molmil](/molmil-images/mine/5zso) | SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec | Descriptor: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | Authors: | Nakamura, R, Fujishiro, T, Takahashi, Y. | Deposit date: | 2018-04-29 | Release date: | 2019-05-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KG1
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![BU of 6kg1 by Molmil](/molmil-images/mine/6kg1) | NifS from Helicobacter pylori, soaked with L-cysteine for 180 sec | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, CHLORIDE ION, Cysteine desulfurase IscS, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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6KG0
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![BU of 6kg0 by Molmil](/molmil-images/mine/6kg0) | NifS from Helicobacter pylori, soaked with L-cysteine for 118 sec | Descriptor: | CHLORIDE ION, Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, ... | Authors: | Nakamura, R, Takahashi, Y, Fujishiro, T. | Deposit date: | 2019-07-09 | Release date: | 2019-10-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
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