1JN6
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![BU of 1jn6 by Molmil](/molmil-images/mine/1jn6) | Crystal Structure of Fab-Estradiol Complexes | 分子名称: | monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain | 著者 | Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B. | 登録日 | 2001-07-23 | 公開日 | 2002-02-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Highly specific anti-estradiol antibodies: structural characterisation and binding diversity. J.Mol.Biol., 315, 2002
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2W50
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![BU of 2w50 by Molmil](/molmil-images/mine/2w50) | N-terminal domain of human conserved dopamine neurotrophic factor (CDNF) | 分子名称: | ARMET-LIKE PROTEIN 1, PHOSPHATE ION | 著者 | Parkash, V, Lindholm, P, Peranen, J, Kalkkinen, N, Oksanen, E, Saarma, M, Leppanen, V.M, Goldman, A. | 登録日 | 2008-12-03 | 公開日 | 2009-03-17 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional. Protein Eng.Des.Sel., 22, 2009
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5WKX
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![BU of 5wkx by Molmil](/molmil-images/mine/5wkx) | Barium sites in the structure of a resting acid sensing ion channel | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | 著者 | Yoder, N, Gouaux, E. | 登録日 | 2017-07-25 | 公開日 | 2018-08-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.034 Å) | 主引用文献 | Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS ONE, 13, 2018
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2VNM
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![BU of 2vnm by Molmil](/molmil-images/mine/2vnm) | Human BACE-1 in complex with 3-(1,1-dioxidotetrahydro-2H-1,2-thiazin- 2-yl)-5-(ethylamino)-N-((1S,2R)-2-hydroxy-1-(phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino)propyl)benzamide | 分子名称: | BETA-SECRETASE 1, N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-3-(1,1-dioxido-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide | 著者 | Charrier, N, Clarke, B, Cutler, L, Demont, E, Dingwall, C, Dunsdon, R, East, P, Hawkins, J, Howes, C, Hussain, I, Jeffrey, P, Maile, G, Matico, R, Mosley, J, Naylor, A, OBrien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | 登録日 | 2008-02-05 | 公開日 | 2008-05-20 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Second Generation of Hydroxyethylamine Bace-1 Inhibitors: Optimizing Potency and Oral Bioavailability. J.Med.Chem., 51, 2008
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4BWJ
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![BU of 4bwj by Molmil](/molmil-images/mine/4bwj) | KlenTaq mutant in complex with DNA and ddCTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*CP)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOCP)-3', ... | 著者 | Blatter, N, Bergen, K, Welte, W, Diederichs, K, Marx, A. | 登録日 | 2013-07-03 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure and Function of an RNA-Reading Thermostable DNA Polymerase. Angew.Chem.Int.Ed.Engl., 52, 2013
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2VS4
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![BU of 2vs4 by Molmil](/molmil-images/mine/2vs4) | THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT) | 分子名称: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Brew, K, Acharya, K.R. | 登録日 | 2008-04-18 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47, 2008
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1GD4
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![BU of 1gd4 by Molmil](/molmil-images/mine/1gd4) | SOLUTION STRUCTURE OF P25S CYSTATIN A | 分子名称: | CYSTATIN A | 著者 | Shimba, N, Kariya, E, Tate, S, Kaji, H, Kainosho, M. | 登録日 | 2000-09-08 | 公開日 | 2001-09-08 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural comparison between wild-type and P25S human cystatin A by NMR spectroscopy. Does this mutation affect the a-helix conformation ? J.STRUCT.FUNCT.GENOM., 1, 2000
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5X0O
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2W7M
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![BU of 2w7m by Molmil](/molmil-images/mine/2w7m) | Crystal structure of Y61AbsSHMT obtained in the presence of Glycine and 5-Formyl tetrahydrofolate | 分子名称: | GLYCINE, PYRIDOXAL-5'-PHOSPHATE, SERINE HYDROXYMETHYLTRANSFERASE | 著者 | Rajaram, V, Bhavani, B.S, Bisht, S, Kaul, P, Prakash, V, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2008-12-22 | 公開日 | 2010-08-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Importance of Tyrosine Residues of Bacillus Stearothermophilus Serine Hydroxymethyltransferase in Cofactor Binding and L-Allo-Thr Cleavage. FEBS J., 275, 2008
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1GAJ
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![BU of 1gaj by Molmil](/molmil-images/mine/1gaj) | CRYSTAL STRUCTURE OF A NUCLEOTIDE-FREE ATP-BINDING CASSETTE FROM AN ABC TRANSPORTER | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, HIGH-AFFINITY BRANCHED CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN, ... | 著者 | Karpowich, N, Yuan, Y.-R, Dai, P.L, Martsinkevich, O, Millen, L, Thomas, P.J, Hunt, J.F. | 登録日 | 2000-11-30 | 公開日 | 2001-07-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter. Structure, 9, 2001
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2W7F
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![BU of 2w7f by Molmil](/molmil-images/mine/2w7f) | Crystal structure of Y51FbsSHMT L-Ser external aldimine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Rajaram, V, Bhavani, B.S, Bisht, S, Kaul, P, Prakash, V, Appaji Rao, N, Savithri, H.S, Murthy, M.R.N. | 登録日 | 2008-12-22 | 公開日 | 2010-08-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Importance of Tyrosine Residues of Bacillus Stearothermophilus Serine Hydroxymethyltransferase in Cofactor Binding and L-Allo-Thr Cleavage. FEBS J., 275, 2008
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5WS0
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![BU of 5ws0 by Molmil](/molmil-images/mine/5ws0) | Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor | 分子名称: | 2-piperazin-1-ylcarbonyl-1H-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1 | 著者 | Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. | 登録日 | 2016-12-04 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor To Be Published
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5WSD
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![BU of 5wsd by Molmil](/molmil-images/mine/5wsd) | Crystal structure of a cupin protein (tm1459) in apo form | 分子名称: | Uncharacterized protein tm1459 | 著者 | Fujieda, N, Nakano, T, Taniguchi, Y, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. | 登録日 | 2016-12-06 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | A Well-Defined Osmium-Cupin Complex: Hyperstable Artificial Osmium Peroxygenase J. Am. Chem. Soc., 2017
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1GC8
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![BU of 1gc8 by Molmil](/molmil-images/mine/1gc8) | THE CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 3-ISOPROPYLMALATE DEHYDROGENASE MUTATED AT 172TH FROM ALA TO PHE | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE | 著者 | Qu, C, Akanuma, S, Tanaka, N, Moriyama, H, Oshima, T. | 登録日 | 2000-07-27 | 公開日 | 2000-09-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design, X-ray crystallography, molecular modelling and thermal stability studies of mutant enzymes at site 172 of 3-isopropylmalate dehydrogenase from Thermus thermophilus. Acta Crystallogr.,Sect.D, 57, 2001
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2W4B
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![BU of 2w4b by Molmil](/molmil-images/mine/2w4b) | Epstein-Barr virus alkaline nuclease D203S mutant | 分子名称: | ALKALINE EXONUCLEASE | 著者 | Buisson, M, Geoui, T, Flot, D, Tarbouriech, N, Burmeister, W.P. | 登録日 | 2008-11-24 | 公開日 | 2009-06-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A Bridge Crosses the Active Site Canyon of the Epstein-Barr Virus Nuclease with DNase and Rnase Activity. J.Mol.Biol., 391, 2009
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1FTM
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2QU9
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![BU of 2qu9 by Molmil](/molmil-images/mine/2qu9) | Crystal structure of the complex of group II phospholipase A2 with Eugenol | 分子名称: | 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | 著者 | Kumar, S, Vikram, G, Singh, N, Sinha, M, Sharma, S, Kaur, P, Srinivasan, A, Singh, T.P. | 登録日 | 2007-08-04 | 公開日 | 2007-08-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Crystal structure of the complex of group II phospholipase A2 with Eugenol To be Published
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2QUJ
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1FW0
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6KZI
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![BU of 6kzi by Molmil](/molmil-images/mine/6kzi) | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives | 分子名称: | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | 登録日 | 2019-09-24 | 公開日 | 2020-03-04 | 最終更新日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. J.Chem.Inf.Model., 60, 2020
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5WZI
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![BU of 5wzi by Molmil](/molmil-images/mine/5wzi) | Structure of APUM23-GGAGUUGACGG | 分子名称: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*GP*UP*UP*GP*AP*CP*GP*G)-3') | 著者 | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | 登録日 | 2017-01-18 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for the specific recognition of 18S rRNA by APUM23. Nucleic Acids Res., 45, 2017
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1G7V
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![BU of 1g7v by Molmil](/molmil-images/mine/1g7v) | CRYSTAL STRUCTURES OF KDO8P SYNTHASE IN ITS BINARY COMPLEXES WITH THE MECHANISM-BASED INHIBITOR | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, {[(2,2-DIHYDROXY-ETHYL)-(2,3,4,5-TETRAHYDROXY-6-PHOSPHONOOXY-HEXYL)-AMINO]-METHYL}-PHOSPHONIC ACID | 著者 | Asojo, O.A, Friedman, J.M, Belakhov, V, Shoham, Y, Adir, N, Baasov, T. | 登録日 | 2000-11-14 | 公開日 | 2001-05-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of KDOP synthase in its binary complexes with the substrate phosphoenolpyruvate and with a mechanism-based inhibitor. Biochemistry, 40, 2001
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4C3X
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![BU of 4c3x by Molmil](/molmil-images/mine/4c3x) | Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 | 分子名称: | 3-KETOSTEROID DEHYDROGENASE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Rohman, A, van Oosterwijk, N, Thunnissen, A.M.W.H, Dijkstra, B.W. | 登録日 | 2013-08-28 | 公開日 | 2013-11-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure and Site-Directed Mutagenesis of 3-Ketosteroid Delta1-Dehydrogenase from Rhodococcus Erythropolis Sq1 Explain its Catalytic Mechanism J.Biol.Chem., 288, 2013
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5WR6
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![BU of 5wr6 by Molmil](/molmil-images/mine/5wr6) | Thermolysin, liganded form with cryo condition 2 | 分子名称: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ... | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | 登録日 | 2016-11-29 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation Acta Crystallogr D Struct Biol, 73, 2017
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1FTO
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