5WS0

Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor

Summary for 5WS0

• Entry DOI: 10.2210/pdb5ws0/pdb
• Related: 5WRQ 5WRY 5WRZ 5WS1
• Descriptor: Poly [ADP-ribose] polymerase 1, 2-piperazin-1-ylcarbonyl-1H-benzimidazole-4-carboxamide (2 entities in total)
• Functional Keywords: inhibitor, complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus: P09874
• Total number of polymer chains: 2
• Total formula weight: 79422.88

Authors

Cao, R.,Wang, Y.L.,Zhou, J.,Huang, N.,Xu, B.L. (deposition date: 2016-12-04, release date: 2017-01-25, Last modification date: 2024-03-20)

• Primary citation: Cao, R.,Wang, Y.L.,Zhou, J.,Huang, N.,Xu, B.L.; Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)