7STR
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![BU of 7str by Molmil](/molmil-images/mine/7str) | Crystal Structure of Human Fab S24-1063 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2 | 分子名称: | 1,2-ETHANEDIOL, Fab S24-1063, Heavy chain, ... | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-11-15 | 公開日 | 2022-08-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies. Iscience, 27, 2024
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6YSB
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![BU of 6ysb by Molmil](/molmil-images/mine/6ysb) | Crystal structure of Malus domestica Double Bond Reductase (MdDBR) apo form | 分子名称: | 2-alkenal reductase (NADP(+)-dependent)-like, SULFATE ION | 著者 | Caliandro, R, Polsinelli, I, Demitri, N, Benini, S. | 登録日 | 2020-04-21 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates. Int.J.Biol.Macromol., 171, 2021
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6YAT
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![BU of 6yat by Molmil](/molmil-images/mine/6yat) | Crystal structure of STK4 (MST1) in complex with compound 6 | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 4-[5-(3-chlorophenyl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine, GLYCEROL, ... | 著者 | Chaikuad, A, Bata, N, Limpert, A.S, Lambert, L.J, Bakas, N.A, Cosford, N.D.P, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-03-13 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia. J.Med.Chem., 65, 2022
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7SNS
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![BU of 7sns by Molmil](/molmil-images/mine/7sns) | 1.55A Resolution Structure of NanoLuc Luciferase | 分子名称: | ACETATE ION, Oplophorus-luciferin 2-monooxygenase catalytic subunit | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | 1.55A Resolution Structure of NanoLuc Luciferase To be published
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6YE2
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7SNX
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![BU of 7snx by Molmil](/molmil-images/mine/7snx) | 1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits | 分子名称: | GLYCEROL, Oplophorus-luciferin 2-monooxygenase catalytic subunit, Oplophorus-luciferin 2-monooxygenase catalytic subunit: C-terminal Peptide (11-mer) | 著者 | Lovell, S, Mehzabeen, N, Battaile, K.P, Wood, M.G, Encell, L.P, Wood, K.V. | 登録日 | 2021-10-28 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.70A Resolution Structure of NanoBiT Complementation Reporter Complex of LgBit and SmBiT Subunits To be published
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7T5J
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![BU of 7t5j by Molmil](/molmil-images/mine/7t5j) | Crystal Structure of Strictosidine Synthase in complex with S-IPA (2-(1H-indol-3-yl) propan-1-amine) | 分子名称: | (2S)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | 登録日 | 2021-12-12 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids to be published
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7T5I
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![BU of 7t5i by Molmil](/molmil-images/mine/7t5i) | Crystal Structure of Strictosidine Synthase in complex with R-IPA(2-(1H-indol-3-yl) propan-1-amine) | 分子名称: | (2R)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | 登録日 | 2021-12-12 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids to be published
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6XZV
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![BU of 6xzv by Molmil](/molmil-images/mine/6xzv) | Structure of zVDR LBD-Calcitriol in complex with chimera 18 | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, URA-UIA-URL-URY-URV-UZN-LYS, Vitamin D3 receptor A | 著者 | Buratto, J, Belorusova, A.Y, Rochel, N, Guichard, G. | 登録日 | 2020-02-05 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for alpha-Helix Mimicry and Inhibition of Protein-Protein Interactions with Oligourea Foldamers. Angew.Chem.Int.Ed.Engl., 60, 2021
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6Y3H
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![BU of 6y3h by Molmil](/molmil-images/mine/6y3h) | NMR solution structure of the hazelnut allergen Cor a 1.0401 | 分子名称: | Major allergen Cor a 1.0401 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6Y3L
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![BU of 6y3l by Molmil](/molmil-images/mine/6y3l) | NMR solution structure of the hazelnut allergen Cor a 1.0404 | 分子名称: | Major allergen variant Cor a 1.0404 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6Y3I
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![BU of 6y3i by Molmil](/molmil-images/mine/6y3i) | NMR solution structure of the hazelnut allergen Cor a 1.0402 | 分子名称: | Major allergen variant Cor a 1.0402 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6YMN
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7TN0
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![BU of 7tn0 by Molmil](/molmil-images/mine/7tn0) | SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-01-20 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022
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6YGU
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![BU of 6ygu by Molmil](/molmil-images/mine/6ygu) | Crystal structure of the minimal Mtr4-Red1 complex (single chain) from Chaetomium thermophilum | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ATP dependent RNA helicase (Dob1)-like protein, ... | 著者 | Dobrev, N, Ahmed, Y.L, Sinning, I. | 登録日 | 2020-03-27 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nat Commun, 12, 2021
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6YFV
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![BU of 6yfv by Molmil](/molmil-images/mine/6yfv) | Crystal structure of Mtr4-Red1 minimal complex from Chaetomium thermophilum | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP dependent RNA helicase (Dob1)-like protein, Red1, ... | 著者 | Dobrev, N, Ahmed, Y.L, Sinning, I. | 登録日 | 2020-03-26 | 公開日 | 2021-05-05 | 最終更新日 | 2021-06-23 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain. Nat Commun, 12, 2021
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6YDH
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6Y3K
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![BU of 6y3k by Molmil](/molmil-images/mine/6y3k) | NMR solution structure of the hazelnut allergen Cor a 1.0403 | 分子名称: | Major allergen variant Cor a 1.0403 | 著者 | Fuehrer, S, Kamenik, A.S, Zeindl, R, Nothegger, B, Hofer, F, Reider, N, Liedl, K.R, Tollinger, M. | 登録日 | 2020-02-18 | 公開日 | 2021-02-17 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens. Sci Rep, 11, 2021
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6YE5
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![BU of 6ye5 by Molmil](/molmil-images/mine/6ye5) | Structure of ribosomal binding factor A RbfA of Staphylococcus aureus bacterium by NMR | 分子名称: | Ribosome-binding factor A | 著者 | Blokhin, D.S, Usachev, K.S, Bikmullin, A.G, Nurullina, L, Garaeva, N, Validov, S, Klochkov, V, Aganov, A, Khusainov, I, Yusupov, M. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of ribosomal binding factor A RbfA of Staphylococcus aureus bacterium by NMR To Be Published
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6YUX
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![BU of 6yux by Molmil](/molmil-images/mine/6yux) | Crystal structure of Malus domestica Double Bond Reductase (MdDBR) ternary complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, ... | 著者 | Caliandro, R, Polsinelli, I, Demitri, N, Benini, S. | 登録日 | 2020-04-27 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates. Int.J.Biol.Macromol., 171, 2021
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6YXY
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![BU of 6yxy by Molmil](/molmil-images/mine/6yxy) | State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | 分子名称: | 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2020-05-04 | 公開日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
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6YSO
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![BU of 6yso by Molmil](/molmil-images/mine/6yso) | Crystal structure of the (SR) Ca2+-ATPase solved by vanadium SAD phasing | 分子名称: | CHLORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A. | 登録日 | 2020-04-22 | 公開日 | 2020-11-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Experimental phasing with vanadium and application to nucleotide-binding membrane proteins. Iucrj, 7, 2020
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6ZFA
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![BU of 6zfa by Molmil](/molmil-images/mine/6zfa) | Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, 6-tungstotellurate(VI), ... | 著者 | Sobala, L.F, Fernandes, P.Z, Hakki, Z, Thompson, A.J, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | 登録日 | 2020-06-16 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proc.Natl.Acad.Sci.USA, 117, 2020
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7TPR
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![BU of 7tpr by Molmil](/molmil-images/mine/7tpr) | Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants | 分子名称: | Nanobody 7A3, Nanobody 8A2, Spike glycoprotein | 著者 | Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J. | 登録日 | 2022-01-25 | 公開日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Camel nanobodies broadly neutralize SARS-CoV-2 variants bioRxiv, 2021
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6Z36
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![BU of 6z36 by Molmil](/molmil-images/mine/6z36) | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118 | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine, AMMONIUM ION, ... | 著者 | Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2020-05-19 | 公開日 | 2020-05-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118 To Be Published
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