7TPR

Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants

Summary for 7TPR

• Entry DOI: 10.2210/pdb7tpr/pdb
• EMDB information: 26062
• Descriptor: Spike glycoprotein, Nanobody 8A2, Nanobody 7A3 (3 entities in total)
• Functional Keywords: neutralization, nanobody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 8
• Total formula weight: 449716.61

Authors

Butay, K.J.,Zhu, J.,Dandey, V.P.,Hong, J.,Kwon, H.J.,Chen, C.Z.,Duan, Z.,Li, D.,Ren, H.,Liang, T.,Martin, N.,Esposito, D.,Ortega-Rodriguez, U.,Xu, M.,Xie, H.,Ho, M.,Cachau, R.,Borgnia, M.J. (deposition date: 2022-01-25, release date: 2022-04-20)

• Primary citation: Hong, J.,Kwon, H.J.,Cachau, R.,Chen, C.Z.,Dandey, V.P.,Martin, N.,Esposito, D.,Ortega-Rodriguez, U.,Xu, M.,Borgnia, M.J.,Xie, H.,Ho, M.; Camel nanobodies broadly neutralize SARS-CoV-2 variants; bioRxiv, 2021; PubMed: 34751270; DOI: 10.1101/2021.10.27.465996

Experimental method

ELECTRON MICROSCOPY (2.39 Å)