6Z36

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118

Summary for 6Z36

• Entry DOI: 10.2210/pdb6z36/pdb
• Descriptor: Activin receptor type I, SULFATE ION, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: kinase, inhibitor complex, receptor, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 71714.08

Authors

Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (deposition date: 2020-05-19, release date: 2020-05-27, Last modification date: 2024-01-24)

• Primary citation: Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)