Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004675 | molecular_function | transmembrane receptor protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007178 | biological_process | cell surface receptor protein serine/threonine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004675 | molecular_function | transmembrane receptor protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007178 | biological_process | cell surface receptor protein serine/threonine kinase signaling pathway |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 801 |
| Chain | Residue |
| A | ARG380 |
| A | ASP438 |
| A | HOH923 |
| A | HOH996 |
| A | HOH1020 |
| A | HOH1023 |
| A | HOH1048 |
| A | HOH1093 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 802 |
| Chain | Residue |
| A | ASP433 |
| A | GLN453 |
| A | ARG454 |
| A | ASN456 |
| A | HOH1031 |
| A | PHE431 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue TAR A 803 |
| Chain | Residue |
| A | GLY217 |
| A | ARG218 |
| A | TYR219 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue Q5Z A 804 |
| Chain | Residue |
| A | VAL214 |
| A | ALA233 |
| A | LYS235 |
| A | LEU281 |
| A | THR283 |
| A | TYR285 |
| A | HIS286 |
| A | GLY289 |
| A | ASP293 |
| A | LYS340 |
| A | ASN341 |
| A | LEU343 |
| A | ALA353 |
| A | ASP354 |
| A | HOH994 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue Q5Z A 805 |
| Chain | Residue |
| A | ARG202 |
| A | VAL204 |
| A | ALA205 |
| A | ARG206 |
| A | TRP227 |
| A | ALA267 |
| A | Q5Z806 |
| A | HOH1052 |
| A | HOH1106 |
| B | ARG206 |
| B | ASP269 |
| B | THR271 |
| B | GLN278 |
| B | TRP280 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue Q5Z A 806 |
| Chain | Residue |
| A | TRP227 |
| A | ILE266 |
| A | ASN459 |
| A | PHE462 |
| A | SER463 |
| A | Q5Z805 |
| A | HOH982 |
| B | SER272 |
| B | ARG273 |
| B | SER276 |
| B | HOH806 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 807 |
| Chain | Residue |
| A | ARG247 |
| A | ARG335 |
| A | LEU357 |
| A | HOH1091 |
| A | HOH1100 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 808 |
| Chain | Residue |
| A | HIS286 |
| A | LYS345 |
| A | LYS346 |
| A | HOH929 |
| A | HOH964 |
| A | HOH977 |
| A | HOH1019 |
| A | HOH1030 |
| A | HOH1050 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | ARG380 |
| B | ASP438 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue NH4 B 602 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue Q5Z B 603 |
| Chain | Residue |
| B | VAL214 |
| B | ALA233 |
| B | LYS235 |
| B | GLU248 |
| B | LEU281 |
| B | THR283 |
| B | TYR285 |
| B | HIS286 |
| B | GLY289 |
| B | PHE324 |
| B | LYS340 |
| B | ASN341 |
| B | LEU343 |
| B | ALA353 |
| B | HOH747 |
| B | HOH807 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 604 |
| Chain | Residue |
| B | HIS286 |
| B | LYS345 |
| B | LYS346 |
| B | HOH748 |
| B | HOH750 |
| B | HOH777 |
| B | HOH883 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 605 |
| Chain | Residue |
| A | ASN459 |
| B | HIS274 |
| B | HOH714 |
| B | HOH772 |
| B | HOH870 |
| A | ASN456 |
| A | PRO458 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 606 |
| Chain | Residue |
| B | ARG218 |
| B | GLY377 |
| B | THR378 |
| B | LYS379 |
| B | HOH707 |
| B | HOH757 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 607 |
| Chain | Residue |
| B | GLU260 |
| B | ILE262 |
| B | LEU263 |
| B | GLY264 |
| B | HIS286 |
| B | HOH701 |
| B | HOH907 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 22 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGKGRYGEVWrGswqgen............VAVK |
| Chain | Residue | Details |
| A | VAL214-LYS235 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IaHrDLKskNILV |
| Chain | Residue | Details |
| A | ILE332-VAL344 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
