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PDB: 51 件

5KUB
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Bacillus cereus DNA glycosylase AlkD bound to 7-methylguanine nucleobase and DNA containing an oxocarbenium-intermediate analog
分子名称: 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, DNA (5'-D(*CP*CP*CP*GP*AP*(NRI)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*CP*TP*CP*GP*GP*G)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2016-07-13
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A Catalytic Role for C-H/ pi Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD.
J.Am.Chem.Soc., 138, 2016
4X8Q
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BU of 4x8q by Molmil
X-ray crystal structure of AlkD2 from Streptococcus mutans
分子名称: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
著者Mullins, E.A, Shi, R, Eichman, B.F.
登録日2014-12-10
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases.
Plos One, 10, 2015
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCW
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BU of 8ucw by Molmil
Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8UCV
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BU of 8ucv by Molmil
Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
著者Mullins, E.A, Chazin, W.C, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
4HL6
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BU of 4hl6 by Molmil
YfdE from Escherichia coli
分子名称: Uncharacterized protein YfdE
著者Mullins, E.A, Sullivan, K.L, Nyffeler, K.E, Kappock, T.J.
登録日2012-10-16
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Function and X-Ray crystal structure of Escherichia coli YfdE.
Plos One, 8, 2013
8G9N
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BU of 8g9n by Molmil
Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-02-21
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9O
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BU of 8g9o by Molmil
Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-02-21
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G99
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BU of 8g99 by Molmil
Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-02-21
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9F
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BU of 8g9f by Molmil
Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-02-21
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8G9L
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BU of 8g9l by Molmil
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-02-21
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5M
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BU of 8v5m by Molmil
Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-11-30
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (9.22 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6J
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BU of 8v6j by Molmil
DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (11.11 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5O
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BU of 8v5o by Molmil
Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-11-30
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (8.99 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6I
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BU of 8v6i by Molmil
DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (14.06 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V5N
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BU of 8v5n by Molmil
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-11-30
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (8.56 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6G
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BU of 8v6g by Molmil
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (11.16 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
8V6H
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BU of 8v6h by Molmil
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
登録日2023-12-01
公開日2023-12-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (11.11 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
5UUG
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BU of 5uug by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing an abasic site (9-mer product complex)
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*GP*CP*AP*(ORP)P*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*TP*GP*CP*C)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2017-02-16
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.712 Å)
主引用文献Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
5UUJ
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BU of 5uuj by Molmil
Streptomyces sahachiroi DNA glycosylase AlkZ
分子名称: AlkZ
著者Mullins, E.A, Eichman, B.F.
登録日2017-02-16
公開日2017-04-12
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structure of a DNA glycosylase that unhooks interstrand cross-links.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UUF
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BU of 5uuf by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing an abasic site (12-mer product complex)
分子名称: DNA (5'-D(*CP*CP*CP*CP*AP*(ORP)P*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*CP*TP*TP*TP*GP*GP*GP*G)-3'), DNA-7-methylguanine glycosylase, ...
著者Mullins, E.A, Eichman, B.F.
登録日2017-02-16
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.612 Å)
主引用文献Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
5UUH
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BU of 5uuh by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a yatakemycin-adenine nucleobase adduct and DNA containing a fluorinated abasic site (9-mer product complex)
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*GP*CP*AP*(ORF)P*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*TP*GP*CP*C)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2017-02-16
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.569 Å)
主引用文献Toxicity and repair of DNA adducts produced by the natural product yatakemycin.
Nat. Chem. Biol., 13, 2017
7LXH
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BU of 7lxh by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a CC1065-adenine nucleobase adduct and DNA containing an abasic site
分子名称: 7-{7-[(1R)-1-{[(4P)-6-amino-3H-purin-3-yl]methyl}-5-hydroxy-8-methyl-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carbonyl]-4-hydroxy-5-methoxy-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carbonyl}-4-hydroxy-5-methoxy-1,6-dihydropyrrolo[3,2-e]indole-3(2H)-carboxamide, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*AP*(ORP)P*GP*GP*C)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2021-03-03
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.667 Å)
主引用文献Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites.
Nat Commun, 12, 2021
7LXJ
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BU of 7lxj by Molmil
Bacillus cereus DNA glycosylase AlkD bound to a duocarmycin SA-adenine nucleobase adduct and DNA containing an abasic site
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*AP*(ORP)P*GP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*CP*TP*TP*TP*GP*C)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2021-03-03
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites.
Nat Commun, 12, 2021
5E5H
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BU of 5e5h by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6) bound to acetate and degradation products from the acetyl-CoA analogue dethiaacetyl-CoA
分子名称: ACETATE ION, ACETYL GROUP, CHLORIDE ION, ...
著者Mullins, E.A, Kappock, T.J.
登録日2015-10-08
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.
Front Chem, 4, 2016

 

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