5E5H

Succinyl-CoA:acetate CoA-transferase (AarCH6) bound to acetate and degradation products from the acetyl-CoA analogue dethiaacetyl-CoA

Replaces:  4FAC

Summary for 5E5H

• Entry DOI: 10.2210/pdb5e5h/pdb
• Related: 4fac 5DW5 5DW6
• Descriptor: Succinyl-CoA:acetate CoA-transferase, CHLORIDE ION, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(propylamino)propyl]amino]butyl] hydrogen phosphate, ... (8 entities in total)
• Functional Keywords: tricarboxylic acid cycle, transferase, acidophile, coenzyme analogue
• Biological source: Acetobacter aceti
• Total number of polymer chains: 2
• Total formula weight: 114190.84

Authors

Mullins, E.A.,Kappock, T.J. (deposition date: 2015-10-08, release date: 2016-05-18, Last modification date: 2023-09-27)

• Primary citation: Murphy, J.R.,Mullins, E.A.,Kappock, T.J.; Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.; Front Chem, 4:23-23, 2016; PubMed: 27242998; DOI: 10.3389/fchem.2016.00023

Experimental method

X-RAY DIFFRACTION (2.052 Å)