8V5N
Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase
Summary for 8V5N
Entry DOI | 10.2210/pdb8v5n/pdb |
EMDB information | 29889 |
Descriptor | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... (5 entities in total) |
Functional Keywords | primase, dna polymerase, chimeric rna-dna primer, rna/dna hybrid, dna replication, dna synthesis, replication, transferase |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 4 |
Total formula weight | 305430.09 |
Authors | Mullins, E.A.,Chazin, W.J.,Eichman, B.F. (deposition date: 2023-11-30, release date: 2023-12-20, Last modification date: 2024-05-29) |
Primary citation | Mullins, E.A.,Salay, L.E.,Durie, C.L.,Bradley, N.P.,Jackman, J.E.,Ohi, M.D.,Chazin, W.J.,Eichman, B.F. A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31:777-790, 2024 Cited by PubMed: 38491139DOI: 10.1038/s41594-024-01227-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (8.56 Å) |
Structure validation
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