1I5N
 
 | | Crystal structure of the P1 domain of CheA from Salmonella typhimurium | | Descriptor: | CHEMOTAXIS PROTEIN CHEA, SULFATE ION | | Authors: | Mourey, L, Da Re, S, Pedelacq, J.-D, Tolstyk, T, Faurie, C, Guillet, V, Stock, J.B, Samama, J.-P. | | Deposit date: | 2001-02-28 | | Release date: | 2001-07-11 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis
J.Biol.Chem., 276, 2001
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1ATT
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1AVB
 | | ARCELIN-1 FROM PHASEOLUS VULGARIS L | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARCELIN-1, ... | | Authors: | Mourey, L, Pedelacq, J.D, Fabre, C, Rouge, P, Samama, J.P. | | Deposit date: | 1997-09-15 | | Release date: | 1998-10-14 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the arcelin-1 dimer from Phaseolus vulgaris at 1.9-A resolution.
J.Biol.Chem., 273, 1998
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1BUL
 | | 6ALPHA-(HYDROXYPROPYL)PENICILLANATE ACYLATED ON NMC-A BETA-LACTAMASE FROM ENTEROBACTER CLOACAE | | Descriptor: | 2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NMC-A BETA-LACTAMASE | | Authors: | Mourey, L, Swaren, P, Miyashita, K, Bulychev, A, Mobashery, S, Samama, J.P. | | Deposit date: | 1998-09-04 | | Release date: | 1998-12-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Inhibition of the Nmc-A B-Lactamase by a Penicillanic Acid Derivative, and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme
J.Am.Chem.Soc., 120, 1998
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1PVL
 | | STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN F COMPONENT FROM STAPHYLOCOCCUS AUREUS | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LEUCOCIDIN | | Authors: | Pedelacq, J.D, Mourey, L, Maveyraud, L, Prevost, G, Samama, J.P. | | Deposit date: | 1999-01-12 | | Release date: | 1999-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins.
Structure Fold.Des., 7, 1999
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3T8X
 | | Crystal structure of human CD1b in complex with synthetic antigenic diacylsulfoglycolipid SGL12 and endogenous spacer | | Descriptor: | 2-O-sulfo-alpha-D-glucopyranosyl 2-O-hexadecanoyl-3-O-[(2E,4S,6S,8S)-2,4,6,8-tetramethyltetracos-2-enoyl]-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | Authors: | Garcia-Alles, L.F, Maveyraud, L, Mourey, L, Julien, S. | | Deposit date: | 2011-08-02 | | Release date: | 2011-10-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural reorganization of the human CD1b Antigen-binding groove for presentation of mycobacterial sulfoglycolipids
To be Published
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1T5R
 | | STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS | | Descriptor: | LukS-PV | | Authors: | Guillet, V, Roblin, P, Keller, D, Prevost, G, Mourey, L. | | Deposit date: | 2004-05-05 | | Release date: | 2004-08-24 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins.
J.Biol.Chem., 279, 2004
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2QK7
 | | A covalent S-F heterodimer of staphylococcal gamma-hemolysin | | Descriptor: | Gamma-hemolysin component A, Gamma-hemolysin component B | | Authors: | Roblin, P, Guillet, V, Maveyraud, L, Mourey, L. | | Deposit date: | 2007-07-10 | | Release date: | 2008-02-19 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins.
Proteins, 71, 2008
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4N2R
 | | Crystal Structure of the alpha-L-arabinofuranosidase UmAbf62A from Ustilago maydis in complex with L-arabinofuranose | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, alpha-L-arabinofuranose, ... | | Authors: | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | | Deposit date: | 2013-10-06 | | Release date: | 2014-01-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
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4N1I
 | | Crystal Structure of the alpha-L-arabinofuranosidase UmAbf62A from Ustilago maidys | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | | Authors: | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | | Deposit date: | 2013-10-04 | | Release date: | 2014-01-15 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
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4N4B
 | | Crystal Structure of the alpha-L-arabinofuranosidase PaAbf62A from Podospora anserina | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | | Deposit date: | 2013-10-08 | | Release date: | 2014-01-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
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6SCR
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4N2Z
 | | Crystal Structure of the alpha-L-arabinofuranosidase PaAbf62A from Podospora anserina in complex with cellotriose | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | | Deposit date: | 2013-10-06 | | Release date: | 2014-01-15 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
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4TRO
 | | Structure of the enoyl-ACP reductase of Mycobacterium tuberculosis InhA, inhibited with the active metabolite of isoniazid | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | | Authors: | Chollet, A, Julien, S, Mourey, L, Maveyraud, L. | | Deposit date: | 2014-06-17 | | Release date: | 2015-04-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach.
J.Struct.Biol., 190, 2015
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4TRM
 | | Structure of the apo form of InhA from Mycobacterium tuberculosis | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH] | | Authors: | Chollet, A, Julien, S, Mourey, L, Maveyraud, L. | | Deposit date: | 2014-06-17 | | Release date: | 2015-04-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach.
J.Struct.Biol., 190, 2015
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5L84
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8OTM
 | | structure of InhA from mycobacterium tuberculosis in complex with N-((1-(3-hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl)-2-oxo-2H-chromene-3-carboxamide | | Descriptor: | 1,2-ETHANEDIOL, 2-oxidanylidene-~{N}-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methyl]chromene-3-carboxamide, ACETATE ION, ... | | Authors: | Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. | | Deposit date: | 2023-04-21 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Eur.J.Med.Chem., 259, 2023
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8OTN
 | | structure of InhA from mycobacterium tuberculosis in complex with inhibitor 7-((1-(3-Hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methoxy)-4-methyl-2H-chromen-2-one | | Descriptor: | 4-methyl-7-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methoxy]chromen-2-one, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. | | Deposit date: | 2023-04-21 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.962 Å) | | Cite: | Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Eur.J.Med.Chem., 259, 2023
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8OTL
 | | structure of InhA from Mycobacterium tuberculosis in complex with 5-(((4-(2-hydroxyphenoxy)benzyl)(octyl)amino)methyl)-2-phenoxyphenol | | Descriptor: | 1,2-ETHANEDIOL, 5-[[octyl-[[4-(2-oxidanylphenoxy)phenyl]methyl]amino]methyl]-2-phenoxy-phenol, ACETATE ION, ... | | Authors: | Tamhaev, R, Maveyraud, L, Chebaiki, M, Lherbet, C, Mourey, L. | | Deposit date: | 2023-04-21 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.108 Å) | | Cite: | Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Bioorg.Chem., 143, 2023
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3O0D
 | | Crystal structure of Lip2 lipase from Yarrowia lipolytica at 1.7 A resolution | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Bordes, F, Tranier, S, Mourey, L, Marty, A. | | Deposit date: | 2010-07-19 | | Release date: | 2010-11-24 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Exploring the conformational states and rearrangements of Yarrowia lipolytica Lipase.
Biophys.J., 99, 2010
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4IYC
 | | Structure of the T244A mutant of the PANTON-VALENTINE LEUCOCIDIN component from STAPHYLOCOCCUS AUREUS | | Descriptor: | LukS-PV | | Authors: | Maveyraud, L, Guerin, F, Lavnetie, B.J, Prevost, G, Mourey, L. | | Deposit date: | 2013-01-28 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
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5MTW
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4J0O
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4IYT
 | | Structure Of The Y184A Mutant Of The PANTON-VALENTINE LEUCOCIDIN S Component From STAPHYLOCOCCUS AUREUS | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LukS-PV | | Authors: | Guerin, F, Laventie, B.J, Prevost, G, Mourey, L, Maveyraud, L. | | Deposit date: | 2013-01-29 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
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4IYA
 | | Structure of the Y250A mutant of the PANTON-VALENTINE LEUCOCIDIN S component from STAPHYLOCOCCUS AUREUS | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, LukS-PV | | Authors: | Maveyraud, L, Guerin, F, Laventie, B.J, Prevost, G, Mourey, L. | | Deposit date: | 2013-01-28 | | Release date: | 2014-01-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
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