4TRM
Structure of the apo form of InhA from Mycobacterium tuberculosis
Summary for 4TRM
Entry DOI | 10.2210/pdb4trm/pdb |
Related | 4TRN 4TRO |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | enoyl reductase, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 6 |
Total formula weight | 171523.92 |
Authors | Chollet, A.,Julien, S.,Mourey, L.,Maveyraud, L. (deposition date: 2014-06-17, release date: 2015-04-29, Last modification date: 2023-12-20) |
Primary citation | Chollet, A.,Mourey, L.,Lherbet, C.,Delbot, A.,Julien, S.,Baltas, M.,Bernadou, J.,Pratviel, G.,Maveyraud, L.,Bernardes-Genisson, V. Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach. J.Struct.Biol., 190:328-337, 2015 Cited by PubMed: 25891098DOI: 10.1016/j.jsb.2015.04.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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