2E4W
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![BU of 2e4w by Molmil](/molmil-images/mine/2e4w) | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3S-ACPD | Descriptor: | (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E4V
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![BU of 2e4v by Molmil](/molmil-images/mine/2e4v) | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with DCG-IV | Descriptor: | (1R,2R)-3-[(S)-amino(carboxy)methyl]cyclopropane-1,2-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EGO
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![BU of 2ego by Molmil](/molmil-images/mine/2ego) | Crystal Structure of Tamalin PDZ Domain | Descriptor: | General receptor for phosphoinositides 1-associated scaffold protein | Authors: | Sugi, T, Oyama, T, Muto, T, Nakanishi, S, Morikawa, K, Jingami, H. | Deposit date: | 2007-03-01 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation Embo J., 26, 2007
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1AF3
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![BU of 1af3 by Molmil](/molmil-images/mine/1af3) | RAT BCL-XL AN APOPTOSIS INHIBITORY PROTEIN | Descriptor: | APOPTOSIS REGULATOR BCL-X | Authors: | Aritomi, M, Kunishima, N, Inohara, N, Ishibashi, Y, Ohta, S, Morikawa, K. | Deposit date: | 1997-03-21 | Release date: | 1997-07-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family. J.Biol.Chem., 272, 1997
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1ISR
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![BU of 1isr by Molmil](/molmil-images/mine/1isr) | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion | Descriptor: | GADOLINIUM ATOM, GLUTAMIC ACID, Metabotropic Glutamate Receptor subtype 1 | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | Deposit date: | 2001-12-21 | Release date: | 2002-03-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc.Natl.Acad.Sci.USA, 99, 2002
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1ISS
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![BU of 1iss by Molmil](/molmil-images/mine/1iss) | Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with an antagonist | Descriptor: | (S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE, Metabotropic Glutamate Receptor subtype 1 | Authors: | Tsuchiya, D, Kunishima, N, Kamiya, N, Jingami, H, Morikawa, K. | Deposit date: | 2001-12-21 | Release date: | 2002-03-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc.Natl.Acad.Sci.USA, 99, 2002
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2EGN
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![BU of 2egn by Molmil](/molmil-images/mine/2egn) | Crystal Structure of Tamalin PDZ Domain in Complex with mGluR5 C-terminal Peptide | Descriptor: | General receptor for phosphoinositides 1-associated scaffold protein, mGluR5 C-terminal peptide | Authors: | Sugi, T, Oyama, T, Muto, T, Nakanishi, S, Morikawa, K, Jingami, H. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation Embo J., 26, 2007
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1D8L
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![BU of 1d8l by Molmil](/molmil-images/mine/1d8l) | E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III | Descriptor: | PROTEIN (HOLLIDAY JUNCTION DNA HELICASE RUVA) | Authors: | Nishino, T, Iwasaki, H, Kataoka, M, Ariyoshi, M, Fujita, T, Shinagawa, H, Morikawa, K. | Deposit date: | 1999-10-25 | Release date: | 2000-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA. J.Mol.Biol., 298, 2000
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2E4Z
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![BU of 2e4z by Molmil](/molmil-images/mine/2e4z) | Crystal structure of the ligand-binding region of the group III metabotropic glutamate receptor | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Metabotropic glutamate receptor 7 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
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1IZ4
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![BU of 1iz4 by Molmil](/molmil-images/mine/1iz4) | |
1IY2
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![BU of 1iy2 by Molmil](/molmil-images/mine/1iy2) | Crystal structure of the FtsH ATPase domain from Thermus thermophilus | Descriptor: | ATP-dependent metalloprotease FtsH, SULFATE ION | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
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1IY0
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![BU of 1iy0 by Molmil](/molmil-images/mine/1iy0) | Crystal structure of the FtsH ATPase domain with AMP-PNP from Thermus thermophilus | Descriptor: | ATP-dependent metalloprotease FtsH, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
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1IXZ
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![BU of 1ixz by Molmil](/molmil-images/mine/1ixz) | Crystal structure of the FtsH ATPase domain from Thermus thermophilus | Descriptor: | ATP-dependent metalloprotease FtsH, MERCURY (II) ION, SULFATE ION | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
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1ISQ
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![BU of 1isq by Molmil](/molmil-images/mine/1isq) | Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide | Descriptor: | Proliferating Cell Nuclear Antigen, replication factor C large subunit | Authors: | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | Deposit date: | 2001-12-19 | Release date: | 2002-10-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Physical interaction between proliferating cell nuclear antigen and
replication factor C from Pyrococcus furiosus Genes Cells, 7, 2002
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1IZ5
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![BU of 1iz5 by Molmil](/molmil-images/mine/1iz5) | Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form | Descriptor: | Proliferating cell nuclear antigen | Authors: | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | Deposit date: | 2002-09-23 | Release date: | 2003-04-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA PROTEIN SCI., 12, 2003
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1IY1
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![BU of 1iy1 by Molmil](/molmil-images/mine/1iy1) | Crystal structure of the FtsH ATPase domain with ADP from Thermus thermophilus | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent metalloprotease FtsH | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
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2YY2
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![BU of 2yy2 by Molmil](/molmil-images/mine/2yy2) | Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Handa, N, Shirouzu, M, Terada, T, Omori, K, Kotera, J, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-27 | Release date: | 2007-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the human Phosphodiesterase 9A catalytic domain To be Published
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2ZVT
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![BU of 2zvt by Molmil](/molmil-images/mine/2zvt) | Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2 | Descriptor: | (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Oyama, T, Shiraki, T, Morikawa, K. | Deposit date: | 2008-11-19 | Release date: | 2009-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands Febs Lett., 583, 2009
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2ZMF
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![BU of 2zmf by Molmil](/molmil-images/mine/2zmf) | Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Authors: | Handa, N, Kishishita, S, Mizohata, E, Omori, K, Kotera, J, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-04-17 | Release date: | 2008-04-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP J.Biol.Chem., 283, 2008
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3AN3
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![BU of 3an3 by Molmil](/molmil-images/mine/3an3) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO3S | Descriptor: | (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
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3AN4
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![BU of 3an4 by Molmil](/molmil-images/mine/3an4) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R | Descriptor: | (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
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5ZR0
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![BU of 5zr0 by Molmil](/molmil-images/mine/5zr0) | Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP | Descriptor: | Maltose-binding periplasmic protein,Trigger factor | Authors: | Kawagoe, S, Nakagawa, H, Kumeta, H, Ishimori, K, Saio, T. | Deposit date: | 2018-04-21 | Release date: | 2018-08-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insight into prolinecis/transisomerization of unfolded proteins catalyzed by the trigger factor chaperone. J. Biol. Chem., 293, 2018
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