Summary for 2ZVT
| Related | 2ZK1 |
|---|---|
| Descriptor | Peroxisome proliferator-activated receptor gamma, (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid (3 entities in total) |
| Functional Keywords | anti parallel helix sandwich, activator, alternative splicing, diabetes mellitus, disease mutation, dna-binding, metal-binding, nucleus, obesity, phosphoprotein, polymorphism, receptor, transcription, transcription regulation, zinc, zinc-finger |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus P37231 |
| Total number of polymer chains | 2 |
| Total molecular weight | 65662.04 |
| Authors | Waku, T.,Oyama, T.,Shiraki, T.,Morikawa, K. (deposition date: 2008-11-19, release date: 2009-10-06, Last modification date: 2011-07-13) |
| Primary citation | Waku, T.,Shiraki, T.,Oyama, T.,Morikawa, K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands Febs Lett., 583:320-324, 2009 PubMed: 19101554 (PDB entries with the same primary citation) DOI: 10.1016/j.febslet.2008.12.017  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
