2ZVT
Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32514.6 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | A, B | (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid | non-polymer | 316.4 | 2 | Chemie (PTG) | |||
| 3 | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 476 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 191 | - | expression tag |
| Ser 192 | - | expression tag |
| His 193 | - | expression tag |
| Met 194 | - | expression tag |
| Ser 285 | Cys 313 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65029.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 632.9 | |
| All* | Total formula weight | 65662.0 |
